Superior limbic keratoconjunctivitis
disease diseaseOn this page
Also known as SLKsuperior limbal keratoconjunctivitisTheodore's superior limbic keratoconjunctivitisTheodore's syndromeTheodores superior limbic keratoconjunctivitisTheodores syndrome
Summary
Superior limbic keratoconjunctivitis (MONDO:0019504) is a disease and 3 clinical trials. A subtype of keratoconjunctivitis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Clinical trials: 3
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | superior limbic keratoconjunctivitis |
| Mondo ID | MONDO:0019504 |
| Orphanet | 88633 |
| ICD-11 | 1962803547 |
| SNOMED CT | 231903005 |
| UMLS | C0339229 |
| MedGen | 573037 |
| GARD | 0010940 |
| Is cancer (heuristic) | no |
Also known as: SLK · superior limbal keratoconjunctivitis · Theodore’s superior limbic keratoconjunctivitis · Theodore’s syndrome · Theodores superior limbic keratoconjunctivitis · Theodores syndrome
Disease family
This is a subtype of keratoconjunctivitis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › disorder of orbital region › eye disorder › corneal disorder › keratitis › keratoconjunctivitis › superior limbic keratoconjunctivitis
Related subtypes (6): phlyctenulosis, neurotrophic keratoconjunctivitis, punctate epithelial keratoconjunctivitis, epidemic keratoconjunctivitis, exposure keratitis, dry eye syndrome
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 3.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 3 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT00167050 | Not specified | UNKNOWN | The Pathogenesis of Superior Limbic Keratoconjunctivitis |
| NCT02160327 | Not specified | UNKNOWN | The Role of Cytokines and Mast Cell in the Pathogenesis of SLK, Conjunctivochalasis, and Dry Eye |
| NCT03731624 | Not specified | UNKNOWN | Diadenosine Polyphosphates and Mucin Associated With Ocular Surface Disorders |
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.