Tendinitis
diseaseOn this page
Also known as inflammation of tendontendon inflammationtendonitis
Summary
Tendinitis (MONDO:0004857) is a disease (an umbrella term covering 6 Mondo subtypes) and 20 clinical trials. Top therapeutic interventions include sumatriptan, bupivacaine, and tizanidine. A subtype of myositis disease — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Umbrella term: 6 Mondo subtypes
- Clinical trials: 20
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | tendinitis |
| Mondo ID | MONDO:0004857 |
| DOID | DOID:971 |
| NCIT | C97141 |
| SNOMED CT | 34840004 |
| UMLS | C0039503 |
| MedGen | 21094 |
| Is cancer (heuristic) | no |
Also known as: inflammation of tendon · tendon inflammation · tendonitis
Disease family
This is a subtype of myositis disease. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › musculoskeletal system disorder › muscle tissue disorder › skeletal muscle disorder › myopathy › myositis disease › tendinitis
Related subtypes (10): idiopathic granulomatous myositis, myositis ossificans, myositis fibrosa, inclusion body myositis, viral myositis, bacterial myositis, fungal myositis, infectious myositis, orbital myositis, idiopathic inflammatory myopathy
Subtypes (6): patellar tendinitis, tibialis tendinitis, Achilles bursitis, calcific tendinitis, tenosynovitis, paratenonitis
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 20.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| PHASE3 | 9 |
| Not specified | 7 |
| PHASE2 | 3 |
| PHASE4 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT04867369 | PHASE4 | COMPLETED | Pecs II Block Versus Surgeon Infiltration for Open Subpectoral Biceps Tenodesis |
| NCT00352625 | PHASE3 | COMPLETED | Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Shoulder, Elbow or Knee Tendonitis or Bursitis |
| NCT00426985 | PHASE3 | TERMINATED | Efficacy and Safety of Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Shoulder, Elbow or Knee Tendonitis or Bursitis |
| NCT00970658 | PHASE3 | UNKNOWN | Efficacy and Safety of Salonsip Compared to Sabiá Plaster |
| NCT01097798 | PHASE3 | UNKNOWN | To Evaluate the Efficacy and Safety Aliviador Compared to Gelol in Patients With Contusions, Sprains, Trauma and Muscle Injury. |
| NCT01161615 | PHASE3 | COMPLETED | MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Tendonitis and Bursitis of the Shoulder |
| NCT01373697 | PHASE3 | UNKNOWN | Study to Assess the Efficacy and Safety of Ibuprofen 50 mg/g Gel Compared to Profenid 25mg/g Gel |
| NCT01506154 | PHASE3 | COMPLETED | Safety & Efficacy Study of MRX-7EAT Patch in the Treatment of Pain of the Shoulder |
| NCT02346786 | PHASE3 | UNKNOWN | Epidemiology of Incidents and Accidents in Sport. Influence of Moisture. |
| NCT07328022 | PHASE3 | COMPLETED | Efficacy and Safety of Etoricoxib/Betamethasone Combination in Acute Bursitis, Tendinitis and Synovitis |
| NCT00447928 | PHASE2 | UNKNOWN | Phase II Dose-Ranging Study of OrthoDerm Patch for Patients With Tennis Elbow |
| NCT00506038 | PHASE2 | TERMINATED | Efficacy Study of Fine Needle Technique on Calcific Tendinitis |
| NCT01600326 | PHASE2 | COMPLETED | A Prospective Comparison of Ultrasound-Guided Percutaneous Platelet-Rich Plasma Injection |
| NCT03390920 | Not specified | NOT_YET_RECRUITING | Evaluation of Outcomes With Umbilical Cord Allograft for Musculoskeletal Conditions Musculoskeletal Conditions |
| NCT06834425 | Not specified | ACTIVE_NOT_RECRUITING | Efficacy of NSAID Peritendinous Injection for Acute Tendinitis |
| NCT00042419 | Not specified | COMPLETED | Work and Health Disparities Among Rural Women |
| NCT00914836 | Not specified | WITHDRAWN | Comparison of 2 Doses of Corticosteroid Subacromial Injections for the Treatment of Painful Shoulder |
| NCT02403687 | Not specified | COMPLETED | Prospective Analgesic Compound Efficacy (PACE) Study |
| NCT02419040 | Not specified | COMPLETED | Treatment of Calcific Tendinitis of the Rotator Cuff |
| NCT02466308 | Not specified | COMPLETED | Long Duration Therapeutic Ultrasound for Tendon Healing |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| SUMATRIPTAN | 4 | 3 |
| BUPIVACAINE | 4 | 2 |
| TIZANIDINE | 4 | 2 |
| BACLOFEN | 4 | 1 |
| BETAMETHASONE SODIUM PHOSPHATE | 4 | 1 |
| CYCLOBENZAPRINE | 4 | 1 |
| ESFLURBIPROFEN | 4 | 1 |
| ETORICOXIB | 4 | 1 |
| FLURBIPROFEN | 4 | 1 |
| MELOXICAM | 4 | 1 |
| MENTHOL | 4 | 1 |
| PRILOCAINE | 4 | 1 |
| LEVOMENTHOL | 3 | 1 |
| ZUCAPSAICIN | 3 | 1 |