Tendinosis

Summary

Tendinosis (MONDO:0100011) is a disease and 13 clinical trials. A subtype of disease of the tendon — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 13

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	tendinosis
Mondo ID	MONDO:0100011
SNOMED CT	724152009
UMLS	C1568363
MedGen	293673
Is cancer (heuristic)	no

Disease family

This is a subtype of disease of the tendon. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › musculoskeletal system disorder › disease of the tendon › tendinosis

Related subtypes (2): tendinitis, tendon sheath disorder

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 13.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	10
PHASE3	1
PHASE2	1
PHASE1/PHASE2	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT00196573	PHASE3	UNKNOWN	Subacromial Decompression Versus Subacromial Bursectomy for Patients With Rotator Cuff Tendinosis
NCT01600326	PHASE2	COMPLETED	A Prospective Comparison of Ultrasound-Guided Percutaneous Platelet-Rich Plasma Injection
NCT02330146	PHASE1/PHASE2	TERMINATED	Safety and Efficacy of RCT-01 in Men and Women With Unilateral, Chronic Achilles Tendinosis
NCT05352139	Not specified	ENROLLING_BY_INVITATION	Treatment of Tendinosis Using the TenJet Hydroresection System
NCT07540806	Not specified	NOT_YET_RECRUITING	Ultrasound-Guided Percutaneous Needle Tenotomy (PNT) vs Percutaneous Ultrasonic Needle Tenotomy (PUT) for Gluteal Tendinosis
NCT02466308	Not specified	COMPLETED	Long Duration Therapeutic Ultrasound for Tendon Healing
NCT02655042	Not specified	WITHDRAWN	Long-Term Follow-up of the Safety and Efficacy of RCT-01 in Men and Women With Unilateral, Chronic Achilles Tendinosis
NCT03090672	Not specified	UNKNOWN	Cellular & Biocellular Regenerative Therapy in Musculoskeletal Pain, Dysfunction,Degenerative or Inflammatory Disease
NCT03504111	Not specified	UNKNOWN	PRINT Trial (Platelet Rich Injection vs Needle Tenotomy)
NCT03987256	Not specified	UNKNOWN	ECRB Tendinopathy: Needling ± PRP After Failure of Rehabilitation
NCT05030402	Not specified	COMPLETED	Efficacy of Maitland Mobilization in Shoulder Pathology
NCT05132959	Not specified	COMPLETED	The Morphometric Parameters of Shoulder and Supraspinatus Tendinosis
NCT06571695	Not specified	COMPLETED	Restoring the Anatomic Tension Relationship of the Long Head of the Biceps During Tenodesis