Thyroid crisis

Summary

Thyroid crisis (MONDO:0006996) is a disease. A subtype of hyperthyroidism — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	thyroid crisis
Mondo ID	MONDO:0006996
EFO	EFO:1001212
MeSH	D013958
DOID	DOID:12837
ICD-11	1215823328
NCIT	C112836
SNOMED CT	29028009
UMLS	C0040127
MedGen	11813
MedDRA	10043705
Is cancer (heuristic)	no

Also known as: thyroid crisis · thyroid crisis (disease) · thyroid storm · thyrotoxic crisis

Data availability: 1 HPO phenotype.

Disease family

This is a subtype of hyperthyroidism. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › endocrine system disorder › thyroid gland disorder › hyperthyroidism › thyroid crisis

Related subtypes (9): toxic diffuse goiter, selective pituitary resistance to thyroid hormone, generalized resistance to thyroid hormone, thyrotoxicosis, familial gestational hyperthyroidism, familial hyperthyroidism due to mutations in TSH receptor, hyperthyroxinemia, familial dysalbuminemic, primary hyperthyroidism, secondary hyperthyroidism

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.