Typhus

Summary

Typhus (MONDO:0001246) is a disease. A subtype of Rickettsiaceae infectious disease — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	typhus
Mondo ID	MONDO:0001246
EFO	EFO:0009117
Orphanet	102023
DOID	DOID:11256
ICD-10-CM	A75
ICD-11	292650041
SNOMED CT	240613006
UMLS	C0041471
MedGen	11976
GARD	0019829
Is cancer (heuristic)	no

Also known as: endemic flea-borne typhus · endemic typhus fever · epidemic louse-borne typhus · exanthematic typhus fever · flea typhus · gaol fever · louse-borne [epidemic] typhus · murine [endemic] typhus · typhus fever · typhus-group rickettsiae disease · typhus-group rickettsiosis

Disease family

This is a subtype of Rickettsiaceae infectious disease. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › disease of primarily extrinsic mechanism › infectious disease › bacterial infectious disease › Rickettsiosis › Rickettsiaceae infectious disease › typhus

Related subtypes (2): spotted fever, rickettsial pneumonia

Subtypes (3): endemic typhus, epidemic louse-borne typhus, scrub typhus

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.