Undifferentiated pancreatic carcinoma with osteoclast-like giant cells

Summary

Undifferentiated pancreatic carcinoma with osteoclast-like giant cells (MONDO:0006479) is a cancer. A subtype of undifferentiated pancreatic carcinoma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Prevalence: <1 / 1 000 000 (Europe) [Orphanet-validated]

Clinical features

Epidemiology

Prevalence records

9 prevalence record(s), Orphanet:

Type	Class	Value	Geography	Validation
Annual incidence	<1 / 1 000 000	0.001	Europe	Validated
Annual incidence	<1 / 1 000 000	0.002	Belgium	Validated
Annual incidence	<1 / 1 000 000	0.006	Czech Republic	Validated
Annual incidence	<1 / 1 000 000	0.003	France	Validated
Annual incidence	<1 / 1 000 000	0.001	Germany	Validated
Annual incidence	<1 / 1 000 000	0.043	Iceland	Validated
Annual incidence	<1 / 1 000 000	0.001	Italy	Validated
Annual incidence	<1 / 1 000 000	0.004	Lithuania	Validated
Annual incidence	<1 / 1 000 000	0.004	Netherlands	Validated

Identifiers

Disease identifiers

Field	Value
Canonical name	undifferentiated pancreatic carcinoma with osteoclast-like giant cells
Mondo ID	MONDO:0006479
EFO	EFO:1000607
Orphanet	424080
DOID	DOID:7718
NCIT	C5723
UMLS	C2007059
MedGen	389157
GARD	0021782
Is cancer (heuristic)	yes

Also known as: OGCT of pancreas · osteoclast-like giant cell neoplasm of pancreas · osteoclast-like giant cell neoplasm of the pancreas · osteoclastic giant cell tumor of pancreas · osteoclastic giant cell tumour of pancreas · pancreatic osteoclast-like giant cell carcinoma · pancreatic osteoclastic giant cell tumor · pancreatic osteoclastic giant cell tumour · pancreatic undifferentiated carcinoma with osteoclast-like giant cells · undifferentiated carcinoma of pancreas with osteoclast-like giant cells · undifferentiated pancreatic carcinoma with osteoclast-like giant cells

Disease family

This is a subtype of undifferentiated pancreatic carcinoma. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › cancer › carcinoma › adenocarcinoma › tubular adenocarcinoma › pancreatic ductal adenocarcinoma › undifferentiated pancreatic carcinoma › undifferentiated pancreatic carcinoma with osteoclast-like giant cells

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.