Urachal cyst
disease diseaseOn this page
Also known as urachal cyst (disease)
Summary
Urachal cyst (MONDO:0018844) is a disease. A subtype of congenital urachal anomaly — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Prevalence: Unknown (Worldwide)
- Phenotypes (HPO): 16
Clinical features
Signs & symptoms
Clinical features (HPO)
16 HPO clinical features (Orphanet curated; top 16 by frequency):
| HPO ID | Term | Frequency |
|---|---|---|
| HP:0000790 | Hematuria | Occasional (5-29%) |
| HP:0001945 | Fever | Occasional (5-29%) |
| HP:0001974 | Leukocytosis | Occasional (5-29%) |
| HP:0002027 | Abdominal pain | Occasional (5-29%) |
| HP:0011227 | Elevated circulating C-reactive protein concentration | Occasional (5-29%) |
| HP:0012085 | Pyuria | Occasional (5-29%) |
| HP:0025143 | Chills | Occasional (5-29%) |
| HP:0025615 | Abscess | Occasional (5-29%) |
| HP:0032169 | Severe infection | Occasional (5-29%) |
| HP:0100518 | Dysuria | Occasional (5-29%) |
| HP:0100525 | Urachus fistula | Occasional (5-29%) |
| HP:0002586 | Peritonitis | Very rare (<1-4%) |
| HP:0002664 | Neoplasm | Very rare (<1-4%) |
| HP:0010766 | Ectopic calcification | Very rare (<1-4%) |
| HP:0010783 | Erythema | Very rare (<1-4%) |
| HP:0031500 | Abdominal mass | Very rare (<1-4%) |
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | urachal cyst |
| Mondo ID | MONDO:0018844 |
| MeSH | D014496 |
| Orphanet | 488 |
| ICD-11 | 1125432593 |
| NCIT | C85216 |
| SNOMED CT | 17234001 |
| UMLS | C0041915 |
| MedGen | 21770 |
| GARD | 0005425 |
| MedDRA | 10065375 |
| Is cancer (heuristic) | no |
Also known as: urachal cyst · urachal cyst (disease)
Data availability: 1 HPO phenotype.
Disease family
This is a subtype of congenital urachal anomaly. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › urinary system disorder › congenital urachal anomaly › urachal cyst
Related subtypes (3): patent urachus, urachal sinus, urachal diverticulum
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 0.
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.