Urticaria, familial localized heat

Summary

Urticaria, familial localized heat (MONDO:0008634) is a disease. A subtype of urticaria — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	urticaria, familial localized heat
Mondo ID	MONDO:0008634
MeSH	C566011
OMIM	191950
UMLS	C1860551
MedGen	395922
Is cancer (heuristic)	no

Also known as: urticaria, familial localized heat

Disease family

This is a subtype of urticaria. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › integumentary system disorder › skin disorder › dermatitis › urticaria › urticaria, familial localized heat

Related subtypes (13): allergic urticaria, physical urticaria, Melkersson-Rosenthal syndrome, pruritic urticarial papules and plaques of pregnancy, urticaria, aquagenic, angioedema, drug rash with eosinophilia and systemic symptoms, cutaneous mastocytosis, cold urticaria, autoimmune urticaria, papular urticaria, idiopathic urticaria, chronic urticaria

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.