Vascular neoplasm

Summary

Vascular neoplasm (MONDO:0024296) is a cancer (an umbrella term covering 16 Mondo subtypes) and 3 clinical trials. Top therapeutic interventions include pembrolizumab. A subtype of cardiovascular neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Umbrella term: 16 Mondo subtypes
• Clinical trials: 3

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	vascular neoplasm
Mondo ID	MONDO:0024296
NCIT	C7388
UMLS	C0282607
MedGen	129202
Anatomy (UBERON)	UBERON:0007798
Is cancer (heuristic)	yes

Also known as: neoplasm of vascular system · neoplasm of vascular tissue · neoplasms, vascular · tumor of vascular system · tumor of vascular tissue · tumors, vascular · tumour of vascular system · tumour of vascular tissue · vascular neoplasm · vascular neoplasms · vascular system neoplasm · vascular system neoplasm (disease) · vascular system tumor · vascular system tumour · vascular tissue neoplasm · vascular tissue tumor · vascular tissue tumour · vascular tumor · vascular tumors · vascular tumour (+1 more)

Disease family

This is a subtype of cardiovascular neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › cardiovascular disorder › cardiovascular neoplasm › vascular neoplasm

Related subtypes (4): cardiovascular organ benign neoplasm, cardiovascular cancer, heart neoplasm, neoplasm of pericardium

Subtypes (16): intravascular angioleiomyoma, hereditary neurocutaneous angioma, diffuse neonatal hemangiomatosis, inverse Klippel-Trenaunay syndrome, vasoproliferative tumor of retina, kaposiform lymphangiomatosis, retinal capillary malformation, pelvis syndrome, blood vessel neoplasm, choroid neoplasm, vascular bone neoplasm, lymphatic vessel neoplasm, benign choroid plexus neoplasm, benign vascular tumor, borderline vascular tumor, littoral cell hemangioma of the spleen

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 3.

Phase distribution (across all retrieved trials)

Phase	Trials
PHASE4	1
PHASE2	1
Not specified	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT04999618	PHASE4	COMPLETED	A New Approach in Laser Surgery Using the Regenerative Solution in Children Diagnosed With Vascular Pathology
NCT02721732	PHASE2	ACTIVE_NOT_RECRUITING	Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic
NCT06453642	Not specified	ACTIVE_NOT_RECRUITING	Evaluation of a Simple-Prep Controlled Embolic

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
PEMBROLIZUMAB	4	1