Vertebrobasilar insufficiency

Summary

Vertebrobasilar insufficiency (MONDO:0001613) is a disease and 4 clinical trials. A subtype of vascular insufficiency disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 4

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	vertebrobasilar insufficiency
Mondo ID	MONDO:0001613
EFO	EFO:1001449
MeSH	D014715
DOID	DOID:13003
ICD-11	1570524591
SNOMED CT	195199008
UMLS	C0042568
MedGen	12075
Is cancer (heuristic)	no

Also known as: vertebrobasilar arterial insufficiency · vertebrobasilar artery syndrome · vertebrobasilar insufficiency

Disease family

This is a subtype of vascular insufficiency disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › cardiovascular disorder › vascular disorder › vascular insufficiency disorder › vertebrobasilar insufficiency

Related subtypes (8): venous insufficiency, congenital mitral valve insufficiency, vertebral artery insufficiency, basilar artery insufficiency, tricuspid valve insufficiency, chronic intestinal vascular insufficiency, aortic valve insufficiency, splenic infarction

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 4.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	4

Top trials by phase / activity

NCT	Phase	Status	Title
NCT00590980	Not specified	COMPLETED	Vertebrobasilar Flow Evaluation and Risk of Transient Ischemic Attack and Stroke (VERiTAS)
NCT02328781	Not specified	COMPLETED	Prospective Evaluation of Safety and Efficacy Vertebral Drug-eluting Stent System
NCT05019391	Not specified	UNKNOWN	Clinical and Radiological Evaluation of Patients With Vertebrobasilar Insufficiency in Assiut University Hospital
NCT05503212	Not specified	COMPLETED	Best Revascularisation Approach for Posterior Circulation Strokes With Isolated Vertebral Artery Occlusions