Virus-associated trichodysplasia spinulosa

Summary

Virus-associated trichodysplasia spinulosa (MONDO:0016455) is a disease and 19 clinical trials. Top therapeutic interventions include atracurium, isoflurane, and propofol. A subtype of viral infectious disease — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Prevalence: <1 / 1 000 000 (Worldwide) [Orphanet-validated]
• Clinical trials: 19

Clinical features

Epidemiology

Prevalence records

2 prevalence record(s), Orphanet:

Type	Class	Value	Geography	Validation
Cases/families		7	Worldwide	Validated
Point prevalence	<1 / 1 000 000		Worldwide	Validated

Identifiers

Disease identifiers

Field	Value
Canonical name	virus-associated trichodysplasia spinulosa
Mondo ID	MONDO:0016455
Orphanet	228379
UMLS	C3267126
MedGen	1432798
GARD	0020592
Is cancer (heuristic)	no

Also known as: Cyclosporine-induced folliculodystrophy · pilomatrix dysplasia · trichodysplasia spinulosa · TS · VATS

Disease family

This is a subtype of viral infectious disease. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › disease of primarily extrinsic mechanism › infectious disease › viral infectious disease › virus-associated trichodysplasia spinulosa

Related subtypes (40): Whitewater Arroyo hemorrhagic fever, exanthema subitum, Zika virus congenital syndrome, common wart, viral labyrinthitis, viral gastritis, vaccinia, viral esophagitis, Kaposi’s sarcoma, contagious pustular dermatitis, epidemic pleurodynia, herpangina, human T-lymphotropic virus 1 infectious disease, lumpy skin disease, milker’s nodule, molluscum contagiosum, Newcastle disease, pharyngoconjunctival fever, pseudorabies, Reoviridae infectious disease, immunodeficiency 32B, focal epithelial hyperplasia, neurolymphomatosis, viral myositis, infective dermatitis associated with HTLV-1, congenital varicella syndrome, viral hemorrhagic fever, arbovirus fever, human infection by orthopoxvirus, congenital Epstein-Barr virus infection, rabies, arbovirus infection, viral eye infection, viral infection of central nervous system, viral respiratory tract infection, Parvoviridae infectious disease, COVID-19–associated multisystem inflammatory syndrome in children, primary viral infectious disease, disease arising from reactivation of latent virus, human betaherpesvirus 5 infectious disease

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 19.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	17
PHASE4	1
PHASE1	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT07496593	PHASE4	ACTIVE_NOT_RECRUITING	Total Intravenous and Balanced Anesthesia in Diabetic Patients Undergoing Video-Assisted Thoracoscopy
NCT06602661	PHASE1	NOT_YET_RECRUITING	Reinforced and Non-Reinforced Staple Lines in Fissureless Lobectomy
NCT06053476	Not specified	RECRUITING	Optimal Postoperative Chest Tube and Pain Management in Patients Surgically Treated for Primary Spontaneous Pneumothorax (Pneumotrial)
NCT06638645	Not specified	RECRUITING	Prolonged Hospital Stay After Thoracoscopic Anatomical Lung Resections
NCT06778720	Not specified	NOT_YET_RECRUITING	Implementing Music Therapy for Video-Assisted Thoracoscopic Surgery Patients: A Quality Improvement Initiative
NCT06838039	Not specified	RECRUITING	Assessing the Impact of Additional Serratus Anterior Block Within 24-Hour on Postoperative Pain After Rhomboid Intercostal Block in VATS Patients
NCT06912399	Not specified	NOT_YET_RECRUITING	Effect of Transauricular Vagus Nerve Stimulation on Postoperative Pain Management in Video Assisted Thoracic Surgery
NCT06924515	Not specified	ENROLLING_BY_INVITATION	The Application Value of Intercostal Suturing in Preventing Postoperative Thoracoscopic Lung Resection Chest Wall Pulmonary Hernia
NCT07065604	Not specified	RECRUITING	Tubeless VATS for Mediastinal Neoplasm
NCT07199699	Not specified	NOT_YET_RECRUITING	Subxiphoid VATS for Giant Mediastinal Teratoma
NCT07577908	Not specified	RECRUITING	Analgesic Efficiency of SIPSPB vs ICNB in VATS Surgery
NCT04950907	Not specified	UNKNOWN	Uniportal Tubeless VATS for the Evaluation of Biopsy for Second-generation Sequencing in Patients With Advanced NSCLC
NCT05187390	Not specified	UNKNOWN	Incidence of Chronic Pain After Video-Assisted Thoracic Surgery
NCT05491239	Not specified	COMPLETED	Optimal Postoperative Pain Management After Lung Surgery (OPtriAL)
NCT06021327	Not specified	UNKNOWN	Comparison Between Erector Spinae Plane Block And Retrolaminar Block In Patients Undergoing VATS.
NCT06957600	Not specified	COMPLETED	The Comparison of Navigational Bronchoscopic and CT-Guided Preoperative Markings in Minimally Invasive Thoracic Surgery
NCT07057531	Not specified	COMPLETED	Tubeless VATS for Lung Cancer Surgery
NCT07271472	Not specified	COMPLETED	Oxidative Stress Effects of TIVA, CIVA, and Balanced Anesthesia in VATS
NCT07395661	Not specified	COMPLETED	Comparison Of Analgesic Methods İn Video-Assisted Thoracoscopic Surgery

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
ATRACURIUM	4	1
ISOFLURANE	4	1
PROPOFOL	4	1