Warty dyskeratoma

Summary

Warty dyskeratoma (MONDO:0019077) is a disease. A subtype of acanthoma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Prevalence: Unknown (Worldwide)
• Phenotypes (HPO): 19

Clinical features

Signs & symptoms

Clinical features (HPO)

19 HPO clinical features (Orphanet curated; top 19 by frequency):

HPO ID	Term	Frequency
HP:0011355	Localized skin lesion	Very frequent (80-99%)
HP:0011368	Epidermal thickening	Very frequent (80-99%)
HP:0031285	Abnormal perifollicular morphology	Very frequent (80-99%)
HP:0100792	Acantholysis	Very frequent (80-99%)
HP:0000464	Abnormality of the neck	Frequent (30-79%)
HP:0001965	Abnormality of the scalp	Frequent (30-79%)
HP:0025103	Umbilicated nodule	Frequent (30-79%)
HP:0025512	Skin-colored papule	Frequent (30-79%)
HP:0030350	Erythematous papule	Frequent (30-79%)
HP:0200016	Acrokeratosis	Frequent (30-79%)
HP:0031445	Oral mucosa nodule	Occasional (5-29%)
HP:0410340	Focal epithelial hyperplasia of oral mucosa	Occasional (5-29%)
HP:0001231	Abnormal fingernail morphology	Very rare (<1-4%)
HP:0001892	Abnormal bleeding	Very rare (<1-4%)
HP:0006477	Abnormality of the alveolar ridges	Very rare (<1-4%)
HP:0012881	Abnormality of the labia majora	Very rare (<1-4%)
HP:0030416	Vulvar neoplasm	Very rare (<1-4%)
HP:0100648	Neoplasm of the tongue	Very rare (<1-4%)
HP:0100737	Abnormal hard palate morphology	Very rare (<1-4%)

Identifiers

Disease identifiers

Field	Value
Canonical name	warty dyskeratoma
Mondo ID	MONDO:0019077
Orphanet	69745
ICD-11	1427186445
NCIT	C4087
SNOMED CT	254676008
UMLS	C0334063
MedGen	137717
GARD	0018899
MedDRA	10068856
Is cancer (heuristic)	no

Also known as: follicular dyskeratoma · isolated follicular keratosis

Disease family

This is a subtype of acanthoma. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › integumentary system disorder › integumentary system benign neoplasm › benign neoplasm of skin › benign epithelial skin neoplasm › acanthoma › warty dyskeratoma

Related subtypes (5): clear cell acanthoma, large cell acanthoma, epidermolytic acanthoma, acantholytic acanthoma, pilar sheath acanthoma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.