2-OCTYL CYANOACRYLATE
drugOn this page
Also known as DermabondLiquibandLiquid bandageLiquivetOctylsealRitelok con 895
Summary
2-Octyl Cyanoacrylate (CHEMBL4297544) is an approved small molecule; indicated across 1 condition including injury.
At a glance
- Status: Approved (max clinical phase 4)
- Modality: Small molecule
- Indications: 1 condition
- Clinical trials: 39
- Chemistry: 209.28 Da · C12H19NO2
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL4297544 |
| Name | 2-OCTYL CYANOACRYLATE |
| Type | Small molecule |
| Max phase | 3 |
| FDA approved | yes |
| PubChem CID | 9815689 |
| Molecular formula | C12H19NO2 |
| Molecular weight | 209.28 |
| InChIKey | CQVWXNBVRLKXPE-UHFFFAOYSA-N |
SMILES: CCCCCCC(C)OC(=O)C(=C)C#N
IUPAC name: octan-2-yl 2-cyanoprop-2-enoate
Also known as: Dermabond, Liquiband, Liquid bandage, Liquivet, Octylseal, Ritelok con 895
Patent coverage: 911 distinct patent families (2,707 SureChEMBL compound mentions), from 1 matched compound structure(s). Mentions count patents naming the compound (not distinct inventions), so promiscuous / reference molecules inflate the mention figure — families are the dedup metric.
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
1 indication (0 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).
| Indication | Trial phase | MONDO | EFO |
|---|---|---|---|
| injury | 1 | MONDO:0021178 | EFO:0000546 |
Clinical trials
Total trials: 39.
Phase distribution
| Phase | Trials |
|---|---|
| Not specified | 34 |
| PHASE3 | 3 |
| PHASE4 | 1 |
| PHASE1 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT02831946 | PHASE4 | UNKNOWN | Suture Versus Glue (Dermabond) Closure During Cesarean Delivery |
| NCT04321967 | PHASE3 | WITHDRAWN | Nitropaste in Breast Reduction |
| NCT04908137 | PHASE3 | UNKNOWN | Use of 2-Octyl Cyanoacrylate (Dermabond) in Neonatal Circumcision: A Randomized Controlled Trial |
| NCT05492721 | PHASE3 | COMPLETED | Comparing Tissue Adhesives in Port Site Closure |
| NCT01008111 | PHASE1 | WITHDRAWN | Wound Healing of Incisional Wounds for Bilateral Hernia Repair |
| NCT02781870 | Not specified | RECRUITING | Laparoscopic Groin Hernia Repair by a 3D ENDOLAP Visible Mesh With or Without LiquiBand Fix 8 Mesh Fixation |
| NCT04059640 | Not specified | ACTIVE_NOT_RECRUITING | PMCF Study of LiquiBand FIX8® OHMF Device |
| NCT06614829 | Not specified | RECRUITING | Patient Reported Experiences and Outcomes Associated with Standard C-Section Wound Closure Versus STRATAFIX/DERMABOND PRINEO Wound Closure (CS-PREO) |
| NCT06921148 | Not specified | RECRUITING | Silk Bioprotein as a Wound Dressing for Double-Incision Mastectomy |
| NCT07295379 | Not specified | NOT_YET_RECRUITING | LIQUIBAND FIX8® for Ventral Incisional Hernia |
| NCT07483411 | Not specified | RECRUITING | Skin Adhesive Plus Intra-cuticular Suture Versus Suture Alone for Cesarean Skin Closure |
| NCT00282633 | Not specified | UNKNOWN | Wound Closure Techniques |
| NCT00524511 | Not specified | TERMINATED | Comparison Study of Wound Closure at Time of Cesarean Delivery: Dermabond Glue Versus Surgical Staples |
| NCT00762905 | Not specified | COMPLETED | Clinical Trial of MedLogic LiquiBand Laparoscopic Versus Dermabond in the Closure of Surgical Incisions |
| NCT01088074 | Not specified | COMPLETED | A Comparative Study of Incision Closure Methods for Total Knee Replacement |
| NCT01313754 | Not specified | COMPLETED | Comparison of Skin Incision Closure Material for the Transobturator Suburethral Sling Procedure |
| NCT01835405 | Not specified | COMPLETED | LiquiBand Versus Dermabond Versus Sutures for Closure of Surgical Wounds |
| NCT02323711 | Not specified | WITHDRAWN | Dressing Versus Glue (2-Octyl Cyanoacrylate) for Coverage of the Skin Incision After Closure During Cesarean Delivery |
| NCT02836990 | Not specified | COMPLETED | Prevena™ vs Dermabond in Groin Wound Infections in Vascular Surgery |
| NCT02926521 | Not specified | WITHDRAWN | Assessing Current Peripheral Nerve Block Catheter Fixation and Dressing Strategies: An Equivalence Study |
| NCT02935426 | Not specified | UNKNOWN | Comparison of Cyanoacrylate Adhesives to Sutures in the Palate After Connective Tissue Graft |
| NCT03010137 | Not specified | TERMINATED | Incisional Negative Pressure Wound Therapy in High Risk Patients Undergoing Panniculectomy: A Prospective Randomized Controlled Trial |
| NCT03134209 | Not specified | COMPLETED | A Study Investigating the Efficacy of Various Wound Closure Devices in Reducing Postoperative Wound Complications |
| NCT03280628 | Not specified | TERMINATED | Trial Comparing Cosmetic Outcomes of Pediatric Laceration Closure Using Skin Glue, Medical Tape Versus Stitches |
| NCT03285542 | Not specified | COMPLETED | Prospective Randomized Trial of Dermabond Prineo in Total Knee Arthroplasty |
| NCT03429374 | Not specified | TERMINATED | Tacks Versus Glue for Mesh Fixation in Laparoscopic Ventral Hernia Repair Treating Defects Between 2 and 5 cm Width |
| NCT03685565 | Not specified | COMPLETED | Facial Lacerations Repaired With Dermabond Compared With Dermabond With Underlying Steristrips in Pediatric Patients |
| NCT03688880 | Not specified | TERMINATED | A Clinical Study to Compare MAR-CUTIS With Dermabond Advanced |
| NCT03899753 | Not specified | TERMINATED | Closure After Total Shoulder Arthroplasty: Prineo vs Dermabond |
| NCT04009213 | Not specified | COMPLETED | A Clinical Study to Evaluate the Clinical Performance and Safety of LiquiBand FIX8® Versus AbsorbaTack™ for Hernia Mesh Fixation and Peritoneal Closure in Groin Hernia Repair |
| NCT04621994 | Not specified | UNKNOWN | Cesarean Wound Closure: Dermabond Versus Steri Strips |
| NCT04740775 | Not specified | COMPLETED | LiquiBand® Exceed™ and LiquiBand® Rapid™ for General Surgery Procedures |
| NCT05278013 | Not specified | UNKNOWN | Utility of 2- Octyl Cyanoacrylate (2-OCA) |
| NCT05449457 | Not specified | COMPLETED | Aesthetic Outcome of Layered Closure vs. Layered Closure Followed by 2-Octyl Cyanoacrylate |
| NCT05876546 | Not specified | COMPLETED | Evaluation of Skin Irritancy and Sensitization of a Liquid Bandage |
| NCT05888311 | Not specified | COMPLETED | Evaluation of the Protection of a Liquid Bandage |
| NCT05903547 | Not specified | COMPLETED | A Skin Glue Versus Subcuticular Suture for Cesarean Closure Study |
| NCT05914311 | Not specified | COMPLETED | Use of Dermabond in Mitigation of Spinal Cord Stimulation (SCS) Trial Lead Migration |
| NCT05981443 | Not specified | COMPLETED | An Analysis of Dermabond vs. Non-Absorbable Sutures in Skin Closure for Brow Ptosis Procedures |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.