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Atlas / Drug / Bifidobacterium Spp.

Bifidobacterium Spp.

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Also known as BifidobacteriaBifidobacteriumBifidobacterium nos

Summary

Bifidobacterium Spp. (CHEMBL4297912) is a phase-3 clinical-stage unknown; indicated across 14 conditions including seasonal allergic rhinitis and irritable bowel syndrome.

At a glance

  • Status: Max clinical phase 3 (not approved)
  • Modality: Unknown
  • Indications: 14 conditions
  • Clinical trials: 44

Identifiers

Drug identity and classification

FieldValue
ChEMBL IDCHEMBL4297912
NameBifidobacterium Spp.
TypeUnknown
Max phase3

Also known as: Bifidobacteria, Bifidobacterium, Bifidobacterium nos, Bifidobacterium spp., BIFIDOBACTERIUM SPP.

Targets

Targets

No target linkage available.

Bioactivity

No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).

Target pathways

No target-pathway data for this drug (no mapped target genes).

Indications & clinical

Indications

13 diseases in clinical trials (phase 1–3, investigational — not approved indications). Highest ChEMBL trial phase per disease; a non-cancer approved use is occasionally logged at phase 3 here.

Disease (in trials)PhaseMONDOEFO
seasonal allergic rhinitis3MONDO:0005324EFO:0003956
irritable bowel syndrome3MONDO:0005052EFO:0000555
stomatitis3MONDO:0004842EFO:1001904
Crohn disease2MONDO:0005011EFO:0000384
ulcerative colitis2MONDO:0005101EFO:0000729
lichen planus, oral2MONDO:0043923EFO:0008517
prediabetes syndrome2MONDO:0006920EFO:1001121
diarrheal disease2MONDO:0001673HP:0002014
type 2 diabetes mellitus2MONDO:0005148MONDO:0005148
bipolar disorder2MONDO:0004985MONDO:0004985
cardiovascular disorder1MONDO:0004995EFO:0000319
celiac disease1MONDO:0005130EFO:0001060
hepatocellular carcinoma1MONDO:0007256EFO:0000182

1 further indication record had no mapped disease name (EFO/MeSH-only) or were duplicates, and are omitted.

Clinical trials

Total trials: 44.

Phase distribution

PhaseTrials
Not specified32
PHASE24
PHASE13
PHASE42
PHASE1/PHASE22
PHASE31

Top trials by phase / activity

NCTPhaseStatusTitle
NCT01641341PHASE4COMPLETEDIrritable Bowel Syndrome Evaluation and Treatment in Primary Care
NCT07296718PHASE4COMPLETEDSingle Vs Multi-strain Probiotics for Preterm Neonates
NCT02807064PHASE3UNKNOWNEffectiveness of Bifidobacteria in Children Affected by Seasonal Allergic Rhinitis
NCT06560879PHASE2ENROLLING_BY_INVITATIONEffectiveness of Probiotics for the Prevention of Gastrointestinal Toxicity in Children With Leukemia
NCT01276626PHASE1/PHASE2COMPLETEDStudy of Bacteria on Mood and Bowel Symptoms in Patients With Irritable Bowel Syndrome
NCT02155972PHASE2TERMINATEDThe Safety and Effectiveness of Probiotic Supplementation on Bipolar Depression
NCT02244047PHASE1/PHASE2COMPLETEDCytokine Profile in Children With Celiac Disease
NCT02520583PHASE2COMPLETEDThe Effects of Probiotic Supplementation on Markers of Muscle Damage and Performance Following Exercise Induced Muscle Damage
NCT03666572PHASE2COMPLETEDPilot of a Prebiotic and Probiotic Trial in Young Infants With Severe Acute Malnutrition
NCT00810160PHASE1COMPLETEDThe Impact of Oligosaccharides and Bifidobacteria on the Intestinal Microflora of Premature Infants
NCT01879098PHASE1COMPLETEDThe Effect of 3 Probiotic Strains on Bile Acids, Satiety, and Inflammation
NCT04029818PHASE1COMPLETEDEvaluation of a Probiotic on LDL-cholesterol Levels
NCT02457338Not specifiedACTIVE_NOT_RECRUITINGInfant Microbiota and Probiotic Intake Study
NCT06639516Not specifiedNOT_YET_RECRUITINGTherapeutic Effect of Bifidobacterium Longum in Patients with Acute Pancreatitis: a Randomized, Double-Blind, Placebo-Controlled Trial
NCT06772090Not specifiedNOT_YET_RECRUITINGProbiotic Supplementation During Cytotoxic Chemotherapy for Solid Tumor Malignancies
NCT06885944Not specifiedNOT_YET_RECRUITINGProbiotics for Preterm Infants
NCT07172139Not specifiedNOT_YET_RECRUITINGTranscranial Magnetic Stimulation and Pharmacologic/Probiotic Interventions for Diarrhea-Predominant IBS
NCT07420231Not specifiedRECRUITINGEvaluation of the Synergistic Effect of Combining a Prebiotic and a Postbiotic on Intestinal Discomfort
NCT07423897Not specifiedACTIVE_NOT_RECRUITINGConsumer Health Study Aims to Evaluate the Safety, Tolerability and Impact of ED02 Probiotic Supplement on Gastrointestinal Outcomes
NCT07466511Not specifiedNOT_YET_RECRUITINGEffect of Bifidobacterium Breve Supplementation on the Onset and Progression of Idiopathic Scoliosis
NCT07562516Not specifiedNOT_YET_RECRUITINGPB-18 Probiotic for Mild to Moderate Depression
NCT00618904Not specifiedCOMPLETEDEfficacy of Probiotic Bacteria in Subjects With IBS or Functional Diarrhea/ Bloating
NCT00737841Not specifiedUNKNOWNEffect of Bifidobacterium on Irritable Bowel Syndrome
NCT01018472Not specifiedCOMPLETEDProbiotics in Infants With Cyanotic Congenital Heart Disease
NCT01316510Not specifiedCOMPLETEDProbiotics in Infants With Gastroschisis
NCT01330095Not specifiedCOMPLETEDEarly Administration of Bifidobacterium to Very Low Birth Weight Infants
NCT01534572Not specifiedCOMPLETEDSignificance of Synbiotics on Inflammation and Proliferation of Colonic Mucosa
NCT01807858Not specifiedUNKNOWNThe Effects of Synbiotics on Morbidity and Mortality in Preterm Infants
NCT03056846Not specifiedCOMPLETEDProbiotics on Stress-associated Gastrointestinal Function in University Students
NCT03095963Not specifiedCOMPLETEDInteraction Between Levothyroxine and Probiotics in Hypothyroid Patients
NCT03222804Not specifiedWITHDRAWNMilk Oriented Microbiota
NCT03330184Not specifiedCOMPLETEDEffectiveness and Safety of Berberine Hydrochloride and Bifidobacterium in People With Abnormal Glucose Level
NCT03434249Not specifiedCOMPLETEDClinical Trial to Evaluate the Efficacy of Bifidobacterium BB-12® in the Treatment of Infantile Colic
NCT03644966Not specifiedCOMPLETEDProbiotics and Multi-Drug Resistant Urinary Tract Infection
NCT03701906Not specifiedCOMPLETEDEffect of a Mixture of New Probiotic Strains in Preterm Infants
NCT04042181Not specifiedUNKNOWNThe Effects of Supplementation of a Probiotic, B. Longum, on BMI and Anthropometric Outcomes in Overweight/Obese Adults.
NCT04297488Not specifiedUNKNOWNProbiotic Supplementation for Those Immune Non-responders With HIV-1 Infection
NCT04911556Not specifiedUNKNOWNthe Effect of Probiotics on Aging Population
NCT05054309Not specifiedCOMPLETEDA Trial to Evaluate the Effects of Bifidobacterium Longum NCC3001 on Intestinal and Psychological Symptoms in Subjects With Irritable Bowel Syndrome
NCT05603455Not specifiedUNKNOWNEffect of Bifidobacterium Adolescentis on Aging in Healthy Adults (45-65 Years)
NCT05965063Not specifiedCOMPLETEDThe Role of Bifidobacterium Intervention in Food Allergic Infants
NCT06287931Not specifiedUNKNOWNProbiotics for Gallstones in Post-bariatric Surgery Patients
NCT06325605Not specifiedCOMPLETEDEfficacy and Safety of Bifidobacterium Combined With High-frequency Transcranial Magnetic Stimulation in the Treatment of Adolescent Depression
NCT06594406Not specifiedCOMPLETEDThe Effect of Oral Bifidobacterium on Exogenous Creatine Absorption in Adult Subjects

Clinical evidence (CIViC)

No CIViC predictive evidence (expected for non-precision-medicine drugs).

Pharmacology

Pharmacogenomics

No PharmGKB pharmacogenomic data curated for this drug.

No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).

About this page

Generated deterministically by Sugi Atlas from primary biomedical databases via BioBTree. Every record on this page traces to a primary source.

Generated
Atlas version
v1.1.4
BioBTree
v2.0.2

Sources 14

This page pulls from 14 datasets indexed by BioBTree:

chebichembl_activitychembl_moleculechembl_targetcivic_evidenceclinical_trialsefogtopdb_ligandmeshmondopatent_compoundpharmgkbpharmgkb_guidelinepubchem