Carboxymethylcellulose Sodium
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Also known as BlandlaxCarmellose sodiumCellufreshCelluviscCmc daicel 2450Daicel 2450Denvercel ph 2008aE 466E 468E-466Gppe pasteIns no.466Ins-466OrabaseSodium carboxymethyl celluloseSodium carboxymethylcelluloseSodium cellulose glycolateSodium cmc
Summary
Carboxymethylcellulose Sodium (CHEMBL2109001) is a phase-3 clinical-stage unknown; indicated across 4 conditions including dry eye syndrome and refractive error.
At a glance
- Status: Max clinical phase 3 (not approved)
- Modality: Unknown
- Indications: 4 conditions
- Clinical trials: 6
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL2109001 |
| Name | Carboxymethylcellulose Sodium |
| Type | Unknown |
| Max phase | 3 |
Also known as: Blandlax, Carboxymethylcellulose sodium, Carmellose sodium, Cellufresh, Celluvisc, Cmc daicel 2450, Daicel 2450, Denvercel ph 2008a, E 466, E 468, E-466, Gppe paste
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
4 indications (0 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).
| Indication | Trial phase | MONDO | EFO |
|---|---|---|---|
| dry eye syndrome | 3 | MONDO:0006733 | EFO:1000906 |
| refractive error | 2 | MONDO:0004892 | HP:0000539 |
| viral conjunctivitis | 2 | MONDO:0043541 | EFO:0008571 |
1 further indication record had no mapped disease name (EFO/MeSH-only) or were duplicates, and are omitted.
Clinical trials
Total trials: 6.
Phase distribution
| Phase | Trials |
|---|---|
| PHASE4 | 2 |
| Not specified | 2 |
| PHASE2/PHASE3 | 1 |
| PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT00809198 | PHASE4 | COMPLETED | Kynex Versus Refresh Plus Study in Subject With Dry Eye |
| NCT02028754 | PHASE4 | COMPLETED | A Study of Sodium Carboxymethylcellulose for Post Cataract Surgery Dry Eye Symptoms |
| NCT00691197 | PHASE2/PHASE3 | COMPLETED | Safety and Acceptability of Using a Rewetting Drop With Contact Lens Wear |
| NCT03418727 | PHASE2 | COMPLETED | Dry Eye Disease Study With Brimonidine |
| NCT01544842 | Not specified | TERMINATED | Tacrolimus Ointment in Oral Lichen Planus |
| NCT02395952 | Not specified | WITHDRAWN | Healing of Persistent Epithelial Defects |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
- Diseases: dry eye syndrome