Clotiazepam
drugOn this page
Also known as ClozanRize
Summary
Clotiazepam (CHEMBL1697737) is an approved small molecule (ATC N05BA21); indicated across 1 condition including anxiety.
At a glance
- Status: Approved (max clinical phase 4)
- Modality: Small molecule
- ATC class: N05BA21
- Indications: 1 condition
- Chemistry: 318.8 Da · C16H15ClN2OS
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL1697737 |
| Name | Clotiazepam |
| Type | Small molecule |
| Max phase | 4 |
| FDA approved | no |
| PubChem CID | 2811 |
| ATC | N05BA21 |
| Molecular formula | C16H15ClN2OS |
| Molecular weight | 318.8 |
| InChIKey | CHBRHODLKOZEPZ-UHFFFAOYSA-N |
SMILES: CCC1=CC2=C(S1)N(C(=O)CN=C2C3=CC=CC=C3Cl)C
IUPAC name: 5-(2-chlorophenyl)-7-ethyl-1-methyl-3H-thieno[2,3-e][1,4]diazepin-2-one
Also known as: Clotiazepam, Clozan, Rize, CLOTIAZEPAM
Patent coverage: 1,397 distinct patent families (4,489 SureChEMBL compound mentions), from 2 matched compound structure(s). One matched structure accounts for 4,434 (99%) of the total. Mentions count patents naming the compound (not distinct inventions), so promiscuous / reference molecules inflate the mention figure — families are the dedup metric.
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
1 indication (1 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).
| Indication | Trial phase | MONDO | EFO |
|---|---|---|---|
| anxiety | 4 | MONDO:0011918 | EFO:0005230 |
Clinical trials
Total trials: 0.
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No CPIC/DPWG dosing guideline or drug-level clinical/variant annotations in PharmGKB for this molecule.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
- Diseases: anxiety