Clotiazepam

drug
On this page

Also known as ClozanRize

Summary

Clotiazepam (CHEMBL1697737) is an approved small molecule (ATC N05BA21); indicated across 1 condition including anxiety.

At a glance

  • Status: Approved (max clinical phase 4)
  • Modality: Small molecule
  • ATC class: N05BA21
  • Indications: 1 condition
  • Chemistry: 318.8 Da · C16H15ClN2OS

Identifiers

Drug identity and classification

FieldValue
ChEMBL IDCHEMBL1697737
NameClotiazepam
TypeSmall molecule
Max phase4
FDA approvedno
PubChem CID2811
ATCN05BA21
Molecular formulaC16H15ClN2OS
Molecular weight318.8
InChIKeyCHBRHODLKOZEPZ-UHFFFAOYSA-N

SMILES: CCC1=CC2=C(S1)N(C(=O)CN=C2C3=CC=CC=C3Cl)C

IUPAC name: 5-(2-chlorophenyl)-7-ethyl-1-methyl-3H-thieno[2,3-e][1,4]diazepin-2-one

Also known as: Clotiazepam, Clozan, Rize, CLOTIAZEPAM

Patent coverage: 1,397 distinct patent families (4,489 SureChEMBL compound mentions), from 2 matched compound structure(s). One matched structure accounts for 4,434 (99%) of the total. Mentions count patents naming the compound (not distinct inventions), so promiscuous / reference molecules inflate the mention figure — families are the dedup metric.

Targets

Targets

No target linkage available.

Bioactivity

No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).

Target pathways

No target-pathway data for this drug (no mapped target genes).

Indications & clinical

Indications

1 indication (1 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).

IndicationTrial phaseMONDOEFO
anxiety4MONDO:0011918EFO:0005230

Clinical trials

Total trials: 0.

Clinical evidence (CIViC)

No CIViC predictive evidence (expected for non-precision-medicine drugs).

Pharmacology

Pharmacogenomics

No CPIC/DPWG dosing guideline or drug-level clinical/variant annotations in PharmGKB for this molecule.

No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).