Colistimethate
drugOn this page
Also known as Colistin methanesulfonic acidColistin sulfomethateColistinmethanesulfonic acid
Summary
Colistimethate (CHEMBL6067483) is an approved unknown; indicated across 1 condition including osteomyelitis.
At a glance
- Status: Approved (max clinical phase 4)
- Modality: Unknown
- Indications: 1 condition
- Clinical trials: 5
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL6067483 |
| Name | Colistimethate |
| Type | Unknown |
| Max phase | 4 |
Also known as: Colistimethate, Colistin methanesulfonic acid, Colistin sulfomethate, Colistinmethanesulfonic acid, colistimethate, COLISTIMETHATE
Parent form; salt/anhydrous children: CHEMBL1201441
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
1 indication (0 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).
| Indication | Trial phase | MONDO | EFO |
|---|---|---|---|
| osteomyelitis | 0 | MONDO:0005246 | EFO:0003102 |
Clinical trials
Total trials: 5.
Phase distribution
| Phase | Trials |
|---|---|
| PHASE4 | 2 |
| Not specified | 2 |
| PHASE3 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT01844778 | PHASE4 | COMPLETED | Ease of Use and Microbial Contamination of Tobramycin Inhalation Powder (TIP) Versus Nebulised Tobramycin Inhalation Solution (TIS) and Nebulised Colistimethate (COLI) |
| NCT05586438 | PHASE4 | COMPLETED | Pharmacokinetics of Colistin in Critically-ill Patients With AKI Who Receive SLED |
| NCT02452047 | PHASE3 | COMPLETED | Efficacy and Safety of Imipenem+Cilastatin/Relebactam (MK-7655A) Versus Colistimethate Sodium+Imipenem+Cilastatin in Imipenem-Resistant Bacterial Infection (MK-7655A-013) |
| NCT06702943 | Not specified | NOT_YET_RECRUITING | Comparing Tigecycline Vs. Colistimethate in CNS Infections |
| NCT06834971 | Not specified | RECRUITING | Colistin Methanesulfonate Sodium Inhalation for Prophylaxis of Ventilator-Associated Pneumonia (CIVAP): A Prospective, Multicentre, Double-Blind, Randomized, Placebo-Controlled Trial |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.