Comfilcon A

Summary

Comfilcon A (CHEMBL2108584) is a phase-3 clinical-stage small molecule.

At a glance

• Status: Max clinical phase 3 (not approved)
• Modality: Small molecule
• Clinical trials: 23

Identifiers

Drug identity and classification

Field	Value
ChEMBL ID	CHEMBL2108584
Name	Comfilcon A
Type	Small molecule
Max phase	3

Also known as: Comfilcon a, NFB-02, COMFILCON A

Targets

Targets

No target linkage available.

Bioactivity

No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).

Target pathways

No target-pathway data for this drug (no mapped target genes).

Indications & clinical

Indications

0 indications (0 at ChEMBL trial phase 4).

Clinical trials

Total trials: 23.

Phase distribution

Phase	Trials
Not specified	22
PHASE1/PHASE2	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT01437319	PHASE1/PHASE2	COMPLETED	Mucin Balls and Corneal Inflammation Events
NCT00762385	Not specified	COMPLETED	Clinical Comparison of Two Silicone-Hydrogel Contact Lenses
NCT00762788	Not specified	COMPLETED	Clinical Trial of Several Contact Lenses in Extended Wear
NCT01180985	Not specified	COMPLETED	Dispensing Evaluation of a Galyfilcon A Prototype Lens and a Marketed Contact Lens
NCT01244516	Not specified	COMPLETED	Multi-Center 2-Week Clinical Evaluation of Three Silicone Hydrogel Contact Lenses
NCT01952665	Not specified	COMPLETED	A Multi-Center Study Comparing the Clinical Performance of Two Silicone Hydrogel Lenses Over 1 Month of Daily Wear
NCT01965288	Not specified	COMPLETED	Clinical Performance of Biofinity Toric Versus Air Optix for Astigmatism
NCT02185105	Not specified	COMPLETED	Clinical Validation of Biofinity Toric MTO (Made To Order) Lenses
NCT02196766	Not specified	COMPLETED	BIOCLEAN FIRST CARE EX in Combination With Biofinity Lens
NCT02328937	Not specified	COMPLETED	Central Corneal Swelling With Silicone Hydrogel Materials
NCT02436005	Not specified	COMPLETED	Dispensing Study for the Phenacite Project
NCT02510820	Not specified	COMPLETED	The Clinical Performance of the Biofinity Contact Lens (Comfilcon A) With Two Lens Care Systems
NCT02515994	Not specified	COMPLETED	Evaluation of a Johnson & Johnson Vision Care Investigational Contact Lens Compared to a Marketed Monthly Replacement Contact Lens
NCT02537730	Not specified	COMPLETED	BIOCLEAN MPS (Multi-Purpose Solution) VII in Combination With Biofinity Lens: A Two Week Crossover Study
NCT02542072	Not specified	COMPLETED	Multi-Center Clinical Evaluation of Two Reusable Soft Contact Lenses
NCT02625233	Not specified	COMPLETED	Clinical Long-Term Evaluation of Approved and Investigational Contact Lenses
NCT02642991	Not specified	COMPLETED	Dispensing Study for a New Study Lens
NCT02815735	Not specified	COMPLETED	Multi-Centre Clinical Evaluation of Two Reusable Soft Contact Lenses
NCT02920957	Not specified	COMPLETED	Performance Comparison Between Comfilcon A and Senofilcon C Lenses
NCT03006458	Not specified	COMPLETED	A Clinical Comparison of 2 Multifocal Toric XR (Extended Range) Contact Lenses
NCT04005885	Not specified	COMPLETED	A Clinical Comparison of Two Daily Disposable Soft Contact Lenses
NCT04195581	Not specified	COMPLETED	A Clinical Evaluation of Two Contact Lenses Used With Three Care Systems
NCT04404725	Not specified	COMPLETED	Comparing Biofinity Toric Multifocal to Ultra Multifocal for Astigmatism

Clinical evidence (CIViC)

No CIViC predictive evidence (expected for non-precision-medicine drugs).

Pharmacology

Pharmacogenomics

No PharmGKB pharmacogenomic data curated for this drug.

Related molecules

Related molecules

No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).