Copper Histidine
drug drugOn this page
Also known as Bishistidine copper(ii) saltCopper histidinateCopper l-histidinateCopper, bis(l-histidinato)-Copper, bis(l-histidinato-n,o)-CUTX-101J1.412.545KZycubo
Summary
Copper Histidine (CHEMBL4297731) is a phase-3 clinical-stage unknown; indicated across 1 condition including menkes disease.
At a glance
- Status: Max clinical phase 3 (not approved)
- Modality: Unknown
- Indications: 1 condition
- Clinical trials: 3
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL4297731 |
| Name | Copper Histidine |
| Type | Unknown |
| Max phase | 3 |
Also known as: Bishistidine copper(ii) salt, Copper histidinate, Copper histidine, Copper l-histidinate, Copper, bis(l-histidinato)-, Copper, bis(l-histidinato-n,o)-, CUTX-101, J1.412.545K, Zycubo, COPPER HISTIDINE
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
1 disease in clinical trials (phase 1–3, investigational — not approved indications). Highest ChEMBL trial phase per disease; a non-cancer approved use is occasionally logged at phase 3 here.
| Disease (in trials) | Phase | MONDO | EFO |
|---|---|---|---|
| Menkes disease | 3 | MONDO:0010651 | MONDO:0010651 |
Clinical trials
Total trials: 3.
Phase distribution
| Phase | Trials |
|---|---|
| PHASE3 | 1 |
| PHASE1/PHASE2 | 1 |
| Not specified | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT00811785 | PHASE3 | COMPLETED | Molecular Bases of Response to Copper Treatment in Menkes Disease, Related Phenotypes, and Unexplained Copper Deficiency |
| NCT00001262 | PHASE1/PHASE2 | COMPLETED | Copper Histidine Therapy for Menkes Diseases |
| NCT04074512 | Not specified | APPROVED_FOR_MARKETING | Copper Histidinate Treatment for Menkes Disease |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
- In clinical trials for: Menkes disease