Faropenem Medoxomil

drug
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Also known as A-0026A0026Faropenem daloxateFropenem daloxateSUN-A0026faropenem-medoxomilfaropenem medoxil

Summary

Faropenem Medoxomil (CHEMBL1257070) is a phase-3 clinical-stage small molecule; indicated across 2 conditions including chronic bronchitis and otitis media.

At a glance

  • Status: Max clinical phase 3 (not approved)
  • Modality: Small molecule
  • Indications: 2 conditions
  • Clinical trials: 2
  • Chemistry: 397.4 Da · C17H19NO8S

Identifiers

Drug identity and classification

FieldValue
ChEMBL IDCHEMBL1257070
NameFaropenem Medoxomil
TypeSmall molecule
Max phase3
FDA approvedno
PubChem CID6918218
Molecular formulaC17H19NO8S
Molecular weight397.4
InChIKeyJQBKWZPHJOEQAO-DVPVEWDBSA-N

SMILES: CC1=C(OC(=O)O1)COC(=O)C2=C(S[C@H]3N2C(=O)[C@@H]3[C@@H](C)O)[C@H]4CCCO4

IUPAC name: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate

Also known as: A-0026, A0026, Faropenem daloxate, Faropenem medoxomil, Fropenem daloxate, SUN-A0026, faropenem medoxomil, FAROPENEM MEDOXOMIL, FAROPENEM DALOXATE, faropenem-medoxomil, faropenem medoxil

Patent coverage: 12 distinct patent families (19 SureChEMBL compound mentions), from 1 matched compound structure(s). Mentions count patents naming the compound (not distinct inventions), so promiscuous / reference molecules inflate the mention figure — families are the dedup metric.

Targets

Targets

No target linkage available.

Bioactivity

No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).

Target pathways

No target-pathway data for this drug (no mapped target genes).

Indications & clinical

Indications

2 indications (0 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).

IndicationTrial phaseMONDOEFO
chronic bronchitis3MONDO:0005607EFO:0006505
otitis media2MONDO:0005441EFO:0004992

Clinical trials

Total trials: 2.

Phase distribution

PhaseTrials
PHASE31
PHASE21

Top trials by phase / activity

NCTPhaseStatusTitle
NCT00255983PHASE3TERMINATEDA Trial to Evaluate the Efficacy and Safety of Faropenem Medoxomil In the Treatment of Chronic Bronchitis
NCT00276042PHASE2COMPLETEDA Trial to Evaluate Faropenem Medoxomil in the Treatment of Acute Otitis Media

Clinical evidence (CIViC)

No CIViC predictive evidence (expected for non-precision-medicine drugs).

Pharmacology

Pharmacogenomics

No PharmGKB pharmacogenomic data curated for this drug.

No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).