Faropenem Medoxomil
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Also known as A-0026A0026Faropenem daloxateFropenem daloxateSUN-A0026faropenem-medoxomilfaropenem medoxil
Summary
Faropenem Medoxomil (CHEMBL1257070) is a phase-3 clinical-stage small molecule; indicated across 2 conditions including chronic bronchitis and otitis media.
At a glance
- Status: Max clinical phase 3 (not approved)
- Modality: Small molecule
- Indications: 2 conditions
- Clinical trials: 2
- Chemistry: 397.4 Da · C17H19NO8S
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL1257070 |
| Name | Faropenem Medoxomil |
| Type | Small molecule |
| Max phase | 3 |
| FDA approved | no |
| PubChem CID | 6918218 |
| Molecular formula | C17H19NO8S |
| Molecular weight | 397.4 |
| InChIKey | JQBKWZPHJOEQAO-DVPVEWDBSA-N |
SMILES: CC1=C(OC(=O)O1)COC(=O)C2=C(S[C@H]3N2C(=O)[C@@H]3[C@@H](C)O)[C@H]4CCCO4
IUPAC name: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
Also known as: A-0026, A0026, Faropenem daloxate, Faropenem medoxomil, Fropenem daloxate, SUN-A0026, faropenem medoxomil, FAROPENEM MEDOXOMIL, FAROPENEM DALOXATE, faropenem-medoxomil, faropenem medoxil
Patent coverage: 12 distinct patent families (19 SureChEMBL compound mentions), from 1 matched compound structure(s). Mentions count patents naming the compound (not distinct inventions), so promiscuous / reference molecules inflate the mention figure — families are the dedup metric.
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
2 indications (0 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).
| Indication | Trial phase | MONDO | EFO |
|---|---|---|---|
| chronic bronchitis | 3 | MONDO:0005607 | EFO:0006505 |
| otitis media | 2 | MONDO:0005441 | EFO:0004992 |
Clinical trials
Total trials: 2.
Phase distribution
| Phase | Trials |
|---|---|
| PHASE3 | 1 |
| PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT00255983 | PHASE3 | TERMINATED | A Trial to Evaluate the Efficacy and Safety of Faropenem Medoxomil In the Treatment of Chronic Bronchitis |
| NCT00276042 | PHASE2 | COMPLETED | A Trial to Evaluate Faropenem Medoxomil in the Treatment of Acute Otitis Media |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
- Diseases: chronic bronchitis