Garlic

Summary

Garlic (CHEMBL2108463) is a phase-3 clinical-stage unknown; indicated across 4 conditions including alopecia areata and denture stomatitis.

At a glance

• Status: Max clinical phase 3 (not approved)
• Modality: Unknown
• Indications: 4 conditions
• Clinical trials: 18

Identifiers

Drug identity and classification

Field	Value
ChEMBL ID	CHEMBL2108463
Name	Garlic
Type	Unknown
Max phase	3

Also known as: Ae-garlic, Allii bulbus, Allii sativi bulbus, Allium arenarium bulb, Allium controversum bulb, Allium longicuspis bulb, Allium ophioscorodon bulb, Allium pekinense bulb, Allium sativum, Allium sativum (garlic) bulb powder, Allium sativum bulb, Allium sativum bulb extract

Targets

Targets

No target linkage available.

Bioactivity

No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).

Target pathways

No target-pathway data for this drug (no mapped target genes).

Indications & clinical

Indications

4 indications (0 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).

Indication	Trial phase	MONDO	EFO
alopecia areata	3	MONDO:0005340	EFO:0004192
denture stomatitis	2	MONDO:0006723	EFO:1000893
follicular lymphoma	2	MONDO:0018906	MONDO:0018906

1 further indication record had no mapped disease name (EFO/MeSH-only) or were duplicates, and are omitted.

Clinical trials

Total trials: 18.

Phase distribution

Phase	Trials
Not specified	14
PHASE4	1
PHASE3	1
PHASE2/PHASE3	1
PHASE2	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT00499460	PHASE4	COMPLETED	Effects of Garlic Supplements on Opioids in Healthy Volunteers
NCT02691117	PHASE3	TERMINATED	Topical Garlic Concentrate for Alopecia Areata in Children
NCT05050071	PHASE2/PHASE3	COMPLETED	Evaluation of Antibacterial Effect of Allium Sativum, Calcium Hydroxide and Their Combination in Infected Mature Teeth
NCT01198223	PHASE2	COMPLETED	Effect of Aqueous Extract of Garlic and Nystatin Mouthwash in Denture Stomatitis
NCT00079170	Not specified	COMPLETED	Docetaxel Plus Garlic in Treating Patients With Locally Advanced or Metastatic Breast Cancer
NCT00122889	Not specified	COMPLETED	Effects of Garlic Supplements on Drug Metabolism
NCT01293591	Not specified	COMPLETED	Garlic Intake And Biomarkers Of Cancer Risk
NCT01948453	Not specified	COMPLETED	Effect of Garlic Tablet Some Indicators Related to Atherosclerosis
NCT02322541	Not specified	WITHDRAWN	Dietary Absorption of Garlic Metabolites Following Garlic Consumption
NCT03125551	Not specified	WITHDRAWN	ROTEM and Dietary Supplements
NCT03795636	Not specified	COMPLETED	Allium Sativum Extract as an Irrigant
NCT04646382	Not specified	COMPLETED	Effect of a Mixture of Allium Extracts on LDL Cholesterol Levels Volunteers With Elevated LDL Cholesterol Levels
NCT04647071	Not specified	COMPLETED	Allium Extracts on the Incidence of Respiratory Infection Symptoms in Healthy Elderly Volunteers
NCT05016999	Not specified	COMPLETED	Allium Extracts on the Intestinal Microbiota in Healthy Resident Volunteers.
NCT05082350	Not specified	UNKNOWN	Nutritional Intervention With Black Garlic
NCT05349253	Not specified	COMPLETED	Effect of Garlic Extracts on Changes in Cerebral Blood Flow
NCT05349604	Not specified	COMPLETED	Effect of Garlic Extracts on Changes in Blood Flow Velocity in the Carotid Artery
NCT05744752	Not specified	UNKNOWN	Effects of Allium Sativum and Moringa Oleifera Extract on Dental Enamel

Clinical evidence (CIViC)

No CIViC predictive evidence (expected for non-precision-medicine drugs).

Pharmacology

Pharmacogenomics

No PharmGKB pharmacogenomic data curated for this drug.

Related molecules

Related molecules

No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).