Ginger
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Also known as Amomum angustifolium wholeAmomum zinziba wholeArdraka wholeB1265Curcuma longifolia wholeFEMA NO. 2520FEMA NO. 2521Gan jiang wholeGarden ginger wholeGinger wholeJiang pi wholeJiang wholePao jiang wholePhillipsSheng jiang wholeShunthi wholeTravel sicknessTravelcapsWbv181a2i6
Summary
Ginger (CHEMBL2108465) is a phase-3 clinical-stage unknown; indicated across 12 conditions including dental caries and acute respiratory distress syndrome.
At a glance
- Status: Max clinical phase 3 (not approved)
- Modality: Unknown
- Indications: 12 conditions
- Clinical trials: 56
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL2108465 |
| Name | Ginger |
| Type | Unknown |
| Max phase | 3 |
Also known as: Amomum angustifolium whole, Amomum zinziba whole, Ardraka whole, B1265, Curcuma longifolia whole, FEMA NO. 2520, FEMA NO. 2521, Gan jiang whole, Garden ginger whole, Ginger, Ginger whole, Jiang pi whole
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
12 indications (0 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).
| Indication | Trial phase | MONDO | EFO |
|---|---|---|---|
| dental caries | 3 | MONDO:0005276 | EFO:0003819 |
| acute respiratory distress syndrome | 2 | MONDO:0006502 | EFO:1000637 |
| infertility disorder | 2 | MONDO:0005047 | EFO:0000545 |
| osteoporosis | 2 | MONDO:0005298 | EFO:0003882 |
| allergic rhinitis | 2 | MONDO:0011786 | EFO:0005854 |
| tooth disorder | 2 | MONDO:0006999 | EFO:1001216 |
| colorectal neoplasm | 2 | MONDO:0005335 | MONDO:0005575 |
| colorectal adenoma | 1 | MONDO:0005484 | EFO:0005406 |
| fatty liver disease | 0 | MONDO:0004790 | HP:0001397 |
| asthma | 0 | MONDO:0004979 | MONDO:0004979 |
2 further indication records had no mapped disease name (EFO/MeSH-only) or were duplicates, and are omitted.
Clinical trials
Total trials: 56.
Phase distribution
| Phase | Trials |
|---|---|
| Not specified | 31 |
| PHASE2 | 12 |
| PHASE4 | 4 |
| EARLY_PHASE1 | 4 |
| PHASE2/PHASE3 | 3 |
| PHASE3 | 1 |
| PHASE1/PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT07190495 | PHASE4 | RECRUITING | Ginger to Prevent Nausea and Vomiting After Laparoscopic Cholecystectomy |
| NCT00317655 | PHASE4 | COMPLETED | Glucosamine Sulphate, Ginger, Ginger-Avocado-Soya and Ginger-Ibuprofen for Chronic Back Pain |
| NCT02809027 | PHASE4 | COMPLETED | Efficacy of Ginger in the Prevention of Abdominal Distention in Post Cesarean Section Patient |
| NCT05221892 | PHASE4 | COMPLETED | Evaluation of Aminobutyric Acid, Glutamic Acid, Calcium, Thiamine, Pyridoxine and Cyanocobalamin as Therapy for Vertigo |
| NCT00040742 | PHASE2/PHASE3 | COMPLETED | Ginger in Treating Nausea in Patients Receiving Chemotherapy for Cancer |
| NCT01733212 | PHASE2/PHASE3 | COMPLETED | Efficacy of Ginger on Intraoperative and Postoperative Nausea and Vomiting in Elective Cesarean Section Patients |
| NCT02535195 | PHASE2/PHASE3 | COMPLETED | Effect of Ginger Supplement on Non-alcoholic Fatty Liver |
| NCT03061916 | PHASE3 | UNKNOWN | Cinnamon and Ginger in Comparison to Chlorhexidine Gluconate 0.2% on Oral Streptococcus Mutans |
| NCT06817018 | PHASE2 | RECRUITING | Ginger Root Extract for Sciatic Pain Individuals |
| NCT00064272 | PHASE2 | COMPLETED | UMCCOP 02-01 Ginger in Treating Nausea and Vomiting in Patients Receiving Chemotherapy for Cancer |
| NCT00065221 | PHASE2 | COMPLETED | Ginger Control of Chemotherapy Induced Nausea and Vomiting |
| NCT00958685 | PHASE2 | COMPLETED | Safety Study of Feeding With Ginger Extract in Acute Respiratory Distress Syndrome |
| NCT01429935 | PHASE2 | UNKNOWN | Anti Inflammatory and Analgesic Effect of Ginger Powder in Dental Pain Model |
| NCT02032251 | PHASE2 | COMPLETED | Reduction of Sperm DNA Fragmentation by Oral Ginger |
| NCT02390648 | PHASE2 | COMPLETED | Efficacy of Ginger as an Adjunctive Prophylaxis for Chemotherapy-induced Nausea and Vomiting |
| NCT02576808 | PHASE2 | COMPLETED | Study of Efficacy and Safety of Ginger Extract Compared With Loratadine for Treatment of Allergic Rhinitis |
| NCT02685618 | PHASE2 | COMPLETED | Endothelial Dysfunction in Resuscitated Cardiac Arrest |
| NCT02701491 | PHASE2 | COMPLETED | Effect of Ginger on Nausea and Vomiting During Acute Gastroenteritis in Children |
| NCT03617900 | PHASE1/PHASE2 | COMPLETED | Efficacy of Ginger Extract (Compare Between the Ginger Preparation of Ancient Concept of Thai Traditional Practitioner, Standard Drug and Placebo) by Using Pain Score to Evaluate After Pain of Three Groups of First Normal Postpartum Women. |
| NCT03626441 | PHASE2 | COMPLETED | The Effect of Ginger on the Incidence of Postoperative Nausea and Vomiting |
| NCT06792812 | PHASE2 | COMPLETED | The Impact of Ginger Mouthwash on the Pregnant Women With Stress and Gingivitis |
| NCT07595640 | EARLY_PHASE1 | NOT_YET_RECRUITING | Effect of Ginger on Heavy Menstrual Bleeding in Women With Coagulation Disorders |
| NCT02289235 | EARLY_PHASE1 | COMPLETED | Effects of Ginger on Nonalcoholic Fatty Liver Disease in T2DM |
| NCT02670941 | EARLY_PHASE1 | TERMINATED | Aromatherapy for Chemotherapy-induced Symptoms |
| NCT03705832 | EARLY_PHASE1 | COMPLETED | Ginger’s Therapeutic Potential in Asthma |
| NCT06446921 | Not specified | NOT_YET_RECRUITING | The Effect of a Ginger Supplement on Digestive Complaints in Healthy Adults Versus a Placebo |
| NCT06515652 | Not specified | RECRUITING | To Compare the Effects of Herbal Medicines With Traditional Allopathic Medicines in Cases of Patients With Metabolic Syndrome |
| NCT06769035 | Not specified | ACTIVE_NOT_RECRUITING | Effect of a Food Supplement with Natural Extracts of Cocoa, Amaranth Seed and Ginger in Overweight or Obese Patients |
| NCT06772974 | Not specified | NOT_YET_RECRUITING | Tablet Ginger Versus Tablet Doxylamine Succinate in Control of Nausea and Vomiting in Pregnancy |
| NCT07081802 | Not specified | NOT_YET_RECRUITING | Effect of Acupuncture and Herbal Medicine on Bowel Recovery After Abdominal Surgery |
| NCT07437222 | Not specified | RECRUITING | Effect of Ginger Capsules on Inflammation, Oxidative Stress, and Endothelial Function |
| NCT07596979 | Not specified | NOT_YET_RECRUITING | Ginger in the Modulation of Inflammatory Cytokines and Oxidative Stress in Patients With Coronary Artery Disease |
| NCT00537875 | Not specified | COMPLETED | Evaluation of the Effect of Zingiber Officinalis on Nausea and Vomiting in Patients Receiving Cisplatin Based Regimens |
| NCT00611156 | Not specified | COMPLETED | Examination of the Effects of Four Different Spices on Energy Metabolism |
| NCT01085019 | Not specified | COMPLETED | Impact of Spices and Herbs on Endothelial Function |
| NCT02044432 | Not specified | COMPLETED | Treatment of Patients With Chronic Osteoarthritis With Ginger Kidney Compress - a Randomized, Controlled Trial |
| NCT02666807 | Not specified | COMPLETED | Effects of Ginger Supplementation on NF-KB in Peripheral Blood Mononuclear Cells in Type 2 Diabetes Mellitus |
| NCT02732379 | Not specified | COMPLETED | Effect of Aromatherapy on Postoperative Nausea, Vomiting |
| NCT02735486 | Not specified | COMPLETED | Acute Effects of Ginger Extract Consumption on Risk Markers of Cardiovascular Disease |
| NCT02882776 | Not specified | COMPLETED | Daily Ginger Drinking and Platelet Function |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
- Diseases: dental caries