Hexamethyl Pararosaniline

Summary

Hexamethyl Pararosaniline (CHEMBL459265) is an approved small-molecule antibacterial agent.

At a glance

• Status: Approved (max clinical phase 4)
• Modality: Small molecule
• Chemistry: 372.5 Da · C25H30N3+

Identifiers

Drug identity and classification

Field	Value
ChEMBL ID	CHEMBL459265
Name	Hexamethyl Pararosaniline
Type	Small molecule
Max phase	4
FDA approved	yes
PubChem CID	3468
ChEBI	CHEBI:77181
Molecular formula	C25H30N3+
Molecular weight	372.5
InChIKey	LGLFFNDHMLKUMI-UHFFFAOYSA-N

SMILES: CN(C)C1=CC=C(C=C1)C(=C2C=CC(=[N+](C)C)C=C2)C3=CC=C(C=C3)N(C)C

IUPAC name: [4-[bis[4-(dimethylamino)phenyl]methylidene]cyclohexa-2,5-dien-1-ylidene]-dimethylazanium

ChEBI definition: An iminium ion that is malachite green cation in which the hydrogen at the para- psition of the monosubstituted phenyl group is replaced by a dimethylamino group.

Pharmacological roles (ChEBI): antibacterial agent, antifungal agent.

Parent form; salt/anhydrous children: CHEMBL64894

Patent coverage: 1,387 distinct patent families (3,444 SureChEMBL compound mentions), from 2 matched compound structure(s). One matched structure accounts for 3,442 (100%) of the total. Mentions count patents naming the compound (not distinct inventions), so promiscuous / reference molecules inflate the mention figure — families are the dedup metric.

Targets

Targets

No target linkage available.

Bioactivity

No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).

Target pathways

No target-pathway data for this drug (no mapped target genes).

Indications & clinical

Indications

0 indications (0 at ChEMBL trial phase 4).

Clinical trials

Total trials: 0.

Clinical evidence (CIViC)

No CIViC predictive evidence (expected for non-precision-medicine drugs).

Pharmacology

Pharmacogenomics

No CPIC/DPWG dosing guideline or drug-level clinical/variant annotations in PharmGKB for this molecule.

Related molecules

Related molecules

No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).