Honey
drug drugOn this page
Also known as Feng miFengmiHoney absoluteRevamil
Summary
Honey (CHEMBL2108391) is a phase-3 clinical-stage unknown; indicated across 12 conditions including injury and severe acute respiratory syndrome.
At a glance
- Status: Max clinical phase 3 (not approved)
- Modality: Unknown
- Indications: 12 conditions
- Clinical trials: 72
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL2108391 |
| Name | Honey |
| Type | Unknown |
| Max phase | 3 |
Also known as: Feng mi, Fengmi, Honey, Honey absolute, Revamil, HONEY
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
9 diseases in clinical trials (phase 1–3, investigational — not approved indications). Highest ChEMBL trial phase per disease; a non-cancer approved use is occasionally logged at phase 3 here.
| Disease (in trials) | Phase | MONDO | EFO |
|---|---|---|---|
| injury | 3 | MONDO:0021178 | EFO:0000546 |
| severe acute respiratory syndrome | 3 | MONDO:0005091 | MONDO:0100096 |
| hepatitis A virus infection | 2 | MONDO:0005790 | EFO:0007305 |
| dilated cardiomyopathy | 2 | MONDO:0005021 | EFO:0009094 |
| breast neoplasm | 2 | MONDO:0021100 | MONDO:0007254 |
| type 1 diabetes mellitus | 2 | MONDO:0005147 | MONDO:0005147 |
| head and neck cancer | 2 | MONDO:0005627 | EFO:0006859 |
| sinusitis | 1 | MONDO:0005961 | EFO:0007486 |
| lichen planus, oral | 1 | MONDO:0043923 | EFO:0008517 |
1 further indication record had no mapped disease name (EFO/MeSH-only) or were duplicates, and are omitted.
Clinical trials
Total trials: 72.
Phase distribution
| Phase | Trials |
|---|---|
| Not specified | 44 |
| PHASE3 | 6 |
| PHASE2/PHASE3 | 6 |
| PHASE4 | 5 |
| PHASE1 | 4 |
| PHASE2 | 3 |
| PHASE1/PHASE2 | 2 |
| EARLY_PHASE1 | 2 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT03738917 | PHASE4 | COMPLETED | Effectiveness of Antitussives, Anticholinergics and Honey Versus Usual Care in Adults With Acute Bronchitis. |
| NCT03862053 | PHASE4 | WITHDRAWN | Manuka Eye Droops for Treatment of Allergy |
| NCT03929224 | PHASE4 | COMPLETED | The Use of Medical Grade Honey in the Prevention of Bone Anchored Hearing Aid Associated Skin Breakdown |
| NCT05946005 | PHASE4 | COMPLETED | Lidocaine, Povidone Iodine, and Honey Application on Second-degree Perineal Tear Healing |
| NCT06201923 | PHASE4 | COMPLETED | The Efficacy of Thyme Honey Mouth Rinse on Polypharmacy-induced Xerostomia |
| NCT00615420 | PHASE3 | COMPLETED | A Randomized Placebo-Controlled Trial of Manuka Honey for Oral Mucositis Due to Radiation Therapy for Cancer |
| NCT01300676 | PHASE2/PHASE3 | COMPLETED | The Effects of Tualang Honey on Postmenopausal Women |
| NCT02987322 | PHASE2/PHASE3 | COMPLETED | Honey in Idiopathic Dilated Cardiomyopathy |
| NCT03641053 | PHASE3 | COMPLETED | Honey Versus Povidone-iodine on Laceration Wounds |
| NCT04292314 | PHASE2/PHASE3 | COMPLETED | Hydroxy Urea, Omega 3, Nigella Sativa,Honey on Oxidative Stress and Iron Chelation in Pediatric Major Thalassemia |
| NCT04323345 | PHASE3 | UNKNOWN | Efficacy of Natural Honey Treatment in Patients With Novel Coronavirus |
| NCT04347382 | PHASE3 | COMPLETED | Honey & Nigella Sativa Trial Against COVID-19 |
| NCT04767087 | PHASE2/PHASE3 | UNKNOWN | Honey and Nigella Sativa in COVID-19 Prophylaxis |
| NCT05025306 | PHASE3 | COMPLETED | Healing Effect of Ziziphus Honey on Extracted Tooth Socket in Humans by Evaluating the Levels of BMP-2 and OPN |
| NCT05631600 | PHASE2/PHASE3 | COMPLETED | Manuka Honey as an Adjunct to Non-surgical Periodontal Therapy: Clinical Study |
| NCT05885906 | PHASE3 | UNKNOWN | Aloe Vera Versus Thyme Honey Mouthwash in Management of Xerostomia in Type 2 Diabetics |
| NCT06220344 | PHASE2/PHASE3 | COMPLETED | Honey Dressing - A Preventive Procedure for Post-Surgical Site Infection. |
| NCT06810752 | PHASE1/PHASE2 | ENROLLING_BY_INVITATION | Thyme Honey for Management of Oral Lichen Planus |
| NCT01350193 | PHASE1/PHASE2 | COMPLETED | Manuka Honey Irrigation After Sinus Surgery |
| NCT01465308 | PHASE2 | COMPLETED | The Effect of Honey on Xerostomia and Oral Mucositis |
| NCT01554566 | PHASE2 | COMPLETED | Metabolic Effects of Honey in Type 1 Diabetes Mellitus |
| NCT02300792 | PHASE2 | COMPLETED | The Effects of Honey, as a Dietary Supplement in Children With Hepatitis A |
| NCT06456060 | PHASE1 | RECRUITING | Efficacy of Pure Honey Dressing in Contrast to Alvogyl in the Resolution of Dry Socket |
| NCT00127686 | PHASE1 | COMPLETED | Effect of Honey and Dextromethorphan on Nocturnal Cough and Sleep |
| NCT03399331 | PHASE1 | COMPLETED | Honey or Olive Oil for Treating Oral Mucositis in Children and Adults With Leukemia Receiving Intensive Chemotherapy |
| NCT05258955 | PHASE1 | COMPLETED | Title: Comparison of Anti-plaque Efficacy of Natural Honey With Chlorhexidine Mouthwash: A Randomized Controlled Trial |
| NCT02679183 | EARLY_PHASE1 | COMPLETED | Medically-Graded Honey Supplementation Formula To Preterm Infants |
| NCT04848259 | EARLY_PHASE1 | COMPLETED | Effect of Honey and Dexamethason on Extraction Healing |
| NCT05937412 | Not specified | RECRUITING | A Comparative Study Between Honey and Alcohol as Topical Skin Disinfectant |
| NCT06107231 | Not specified | ACTIVE_NOT_RECRUITING | WHNRC (Western Human Nutrition Research Center) Honey Study |
| NCT06421038 | Not specified | NOT_YET_RECRUITING | Efficacy of Thyme Honey in The Management of Oral Aphthous Ulcers |
| NCT06562257 | Not specified | RECRUITING | Honey as A Wound Care Modality in Treating Deep Neck Space Abscess |
| NCT01062256 | Not specified | COMPLETED | Study of Count Coughs in Subjects With Acute Upper Respiratory Tract Infections |
| NCT01371266 | Not specified | COMPLETED | Glycemic Effects of Honey |
| NCT01431729 | Not specified | COMPLETED | Honey and a Mixture of Honey, Beeswax and Olive Oil-propolis Extract in Treatment of Chemotherapy-induced Oral Mucositis |
| NCT01462916 | Not specified | TERMINATED | Honey in Chronic Immune Thrombocytopenia |
| NCT01575821 | Not specified | COMPLETED | The Effect of Honey on Nocturnal Cough and Sleep Quality |
| NCT01615588 | Not specified | COMPLETED | The Glycaemic Index of Manuka Honey |
| NCT02125851 | Not specified | COMPLETED | Comparison of Esophageal Clearance Times of Oral Budesonide Preparations |
| NCT02272673 | Not specified | COMPLETED | The Effects of Honey on Febrile Neutropenia in Children With Acute Lymphoblastic Leukemia |
| NCT02483741 | Not specified | COMPLETED | The Use of Manuka Honey to Improve Healing After Third Molars Surgery |
| NCT03296020 | Not specified | UNKNOWN | The Efficacy of Honey on Improving the Post Surgical Course After Tonsillectomy in Children-prospective Study |
| NCT03331757 | Not specified | COMPLETED | Determination of Glycemic Index of Six Greek Honey Grades |
| NCT03391310 | Not specified | COMPLETED | Use of Honey for Pressure Ulcers in Critically Ill Children |
| NCT03551613 | Not specified | COMPLETED | Effect of Honey Supplementation on Serum Leptin in Malnourished Infants and Children |
| NCT03567395 | Not specified | COMPLETED | Honey to Improve Sleep Quality: a Feasibility Study |
| NCT03670420 | Not specified | COMPLETED | The Application of Honey on Perineal Sutures |
| NCT03826537 | Not specified | COMPLETED | A Study of How Tutin and Hyenanchin, Two Toxins Found in Honey, Are Absorbed and Processed by the Body |
| NCT03931395 | Not specified | COMPLETED | Honey Used as Adjunct Therapy to Tylenol for Post-Op Tonsillectomy Patients |
| NCT04030884 | Not specified | COMPLETED | The Effect of Oral Honey and Water Up to Two Hours Before Surgery on Postoperative Nausea and Vomiting |
| NCT04153617 | Not specified | COMPLETED | Enriched Honey With Soluble Fiber and Polyphenols on Satiety and Dyslipidemia |
| NCT04382079 | Not specified | COMPLETED | Honey Products for Cancer Patients With Oral Mucositis: a Randomized Controlled Trial |
| NCT04438590 | Not specified | COMPLETED | Kelulut Honey as an Alternate Source of Carbo-Loading in Abdominal Surgery Involving the Digestive System |
| NCT04831112 | Not specified | COMPLETED | Compare Effects of Dressing With Honey and EUSOL |
| NCT04843644 | Not specified | UNKNOWN | Microbiota and Symptom Distress in Head and Neck Cancer Patients Receiving Radiotherapy |
| NCT04910919 | Not specified | WITHDRAWN | Here’s the Buzz: Evaluating Pediatric Post Op Pain and Nausea Following Tonsillectomy Surgery |
| NCT04974450 | Not specified | UNKNOWN | Trigona Honey and Intestinal Microbiota Among Obese People |
| NCT05161403 | Not specified | UNKNOWN | The Efficacy of Hyaluronic Acid and Honey in Healing of Multiple Extraction Sockets of Primary Teeth Compared to Saline |
| NCT05231096 | Not specified | COMPLETED | Comparison of the Effect of Gingival Massage of Aloe-vera Gel and Sidr Honey on Chronic Periodontitis |
| NCT05247008 | Not specified | COMPLETED | Effectiveness of Thyme Honey in Management of Xerostomia in ESRD |
| NCT05264428 | Not specified | UNKNOWN | The Effect of Honey on Lessening the Withdrawal Symptoms |
| NCT05427799 | Not specified | COMPLETED | The Influence of Daily Honey Consumption on IR in Obese Women With IR |
| NCT05568563 | Not specified | COMPLETED | Comparison of Effectiveness of Pre-cooling With Ethyl Chloride Versus Honey |
| NCT05625841 | Not specified | UNKNOWN | Effects for Oral Mucositis Care During Chemoradiotherapy in Cancer Patients: Evaluation of the Bee Products |
| NCT05643599 | Not specified | COMPLETED | The Relationship With Mad Honey Containing Grayanotoxin and Ovary Tissue |
| NCT05648682 | Not specified | COMPLETED | Comparison of the Effectiveness of Three Different Gargates in Radiotherapy-Associated Oral Mucositis |
| NCT06201975 | Not specified | UNKNOWN | Efficacy of Thyme Honey as a Novel Adjunct to Non-surgical Periodontal Therapy |
| NCT06240806 | Not specified | COMPLETED | Efficacy of Manuka Honey Oral Rinse in Treatment of Xerostomia |
| NCT06393777 | Not specified | UNKNOWN | Effectiveness of Pre-administered Natural Sweet-tasting Solution (Honey) for Decreasing Pain of Needle Insertion |
| NCT06715800 | Not specified | COMPLETED | Honey Against Sore Throat |
| NCT06840574 | Not specified | SUSPENDED | The Effect of Nutritional Supplementation on Actinic Purpura: A Pilot Study |
| NCT07144969 | Not specified | COMPLETED | Chewing Gum vs Honey in Postoperative Recovery After Ileostomy Reversal: A Study Comparing Their Effects on Bowel Function, Complications, and Hospital Stay |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).