Hyaluronidase (Ovine)

Summary

Hyaluronidase (Ovine) (CHEMBL2108607) is a phase-3 clinical-stage enzyme.

At a glance

• Status: Max clinical phase 3 (not approved)
• Modality: Enzyme
• Clinical trials: 6

Identifiers

Drug identity and classification

Field	Value
ChEMBL ID	CHEMBL2108607
Name	Hyaluronidase (Ovine)
Type	Enzyme
Max phase	3

Also known as: Diffusin, Enzodase, Hyaluronidase (ovine), Hyaluronidase, ovine, Hyazyme, HYO-6A, HYO6A, Vitrase, Wydase, HYALURONIDASE (OVINE)

Targets

Targets

No target linkage available.

Bioactivity

No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).

Target pathways

No target-pathway data for this drug (no mapped target genes).

Indications & clinical

Indications

0 indication records carry no mapped disease name (EFO/MeSH-only); none shown.

Clinical trials

Total trials: 6.

Phase distribution

Phase	Trials
PHASE3	3
PHASE1	2
PHASE2	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT00198484	PHASE3	COMPLETED	Evaluation of Vitrase as a Spreading Agent
NCT00198497	PHASE3	COMPLETED	Safety and Efficacy Study of Vitrase for Clearance of Severe Vitreous Hemorrhage
NCT00198510	PHASE3	COMPLETED	Safety and Efficacy Study of Vitrase for Clearance of Severe Vitreous Hemorrhage
NCT00198471	PHASE2	COMPLETED	Assessment of Intravitreous Injections of Vitrase for Inducing Posterior Vitreous Detachment
NCT00198419	PHASE1	COMPLETED	Hypersensitivity Reaction to Vitrase (Ovine Hyaluronidase)
NCT00198458	PHASE1	COMPLETED	Hypersensitivity Reaction to Vitrase (Ovine Hyaluronidase)

Clinical evidence (CIViC)

No CIViC predictive evidence (expected for non-precision-medicine drugs).

Pharmacology

Pharmacogenomics

No PharmGKB pharmacogenomic data curated for this drug.

Related molecules

Related molecules

No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).