Idraparinux

drug
On this page

Also known as SR 34006SR-34006Sr34006

Summary

Idraparinux (CHEMBL5314801) is a phase-3 clinical-stage oligosaccharide; indicated across 1 condition including pulmonary embolism.

At a glance

  • Status: Max clinical phase 3 (not approved)
  • Modality: Oligosaccharide
  • Indications: 1 condition
  • Clinical trials: 1
  • Chemistry: 1529.4 Da · C38H64O49S7

Identifiers

Drug identity and classification

FieldValue
ChEMBL IDCHEMBL5314801
NameIdraparinux
TypeOligosaccharide
Max phase3
FDA approvedno
PubChem CID3083445
Molecular formulaC38H64O49S7
Molecular weight1529.4
InChIKeyAJBMORBNKXNZSF-COSHMZDQSA-N

SMILES: CO[C@@H]1[C@H](O[C@@H]([C@@H]([C@H]1OC)OC)O[C@H]2[C@@H]([C@H]([C@@H](O[C@@H]2C(=O)O)O[C@@H]3[C@H](O[C@@H]([C@@H]([C@H]3OS(=O)(=O)O)OS(=O)(=O)O)O[C@H]4[C@@H]([C@H]([C@@H](O[C@H]4C(=O)O)O[C@@H]5[C@H](O[C@@H]([C@@H]([C@H]5OS(=O)(=O)O)OS(=O)(=O)O)OC)COS(=O)(=O)O)OC)OC)COS(=O)(=O)O)OC)OC)COS(=O)(=O)O

IUPAC name: (2S,3S,4S,5R,6R)-6-[(2R,3R,4S,5R,6R)-6-[(2R,3S,4S,5R,6R)-2-carboxy-4,5-dimethoxy-6-[(2R,3R,4S,5R,6S)-6-methoxy-4,5-disulfooxy-2-(sulfooxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-4,5-disulfooxy-2-(sulfooxymethyl)oxan-3-yl]oxy-4,5-dimethoxy-3-[(2R,3R,4S,5R,6R)-3,4,5-trimethoxy-6-(sulfooxymethyl)oxan-2-yl]oxyoxane-2-carboxylic acid

Also known as: Idraparinux, SR 34006, SR-34006, Sr34006, IDRAPARINUX

Parent form; salt/anhydrous children: CHEMBL5314374

Patent coverage: 3 distinct patent families (9 SureChEMBL compound mentions), from 1 matched compound structure(s). Mentions count patents naming the compound (not distinct inventions), so promiscuous / reference molecules inflate the mention figure — families are the dedup metric.

Targets

Targets

No target linkage available.

Bioactivity

No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).

Target pathways

No target-pathway data for this drug (no mapped target genes).

Indications & clinical

Indications

1 indication (0 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).

IndicationTrial phaseMONDOEFO
pulmonary embolism3MONDO:0005279EFO:0003827

Clinical trials

Total trials: 1.

Phase distribution

PhaseTrials
PHASE31

Top trials by phase / activity

NCTPhaseStatusTitle
NCT00062803PHASE3COMPLETEDSR34006 Compared to Vitamin K Antagonist (VKA) in the Treatment of Pulmonary Embolism

Clinical evidence (CIViC)

No CIViC predictive evidence (expected for non-precision-medicine drugs).

Pharmacology

Pharmacogenomics

No CPIC/DPWG dosing guideline or drug-level clinical/variant annotations in PharmGKB for this molecule.

No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).