Inulin
drugOn this page
Also known as Chicory root inulinInulin and sodium chlorideInulin component of iqp-ae-103
Summary
Inulin (CHEMBL1201646) is an approved unknown; indicated across 4 conditions including metabolic syndrome x and obesity disorder.
At a glance
- Status: Approved (max clinical phase 4)
- Modality: Unknown
- Indications: 4 conditions
- Clinical trials: 107
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL1201646 |
| Name | Inulin |
| Type | Unknown |
| Max phase | 4 |
Also known as: Chicory root inulin, Inulin, Inulin and sodium chloride, Inulin component of iqp-ae-103, INULIN
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
4 indications (0 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).
| Indication | Trial phase | MONDO | EFO |
|---|---|---|---|
| metabolic syndrome X | 3 | MONDO:0011565 | EFO:0000195 |
| obesity disorder | 2 | MONDO:0011122 | EFO:0001073 |
| gastroenteritis | 1 | MONDO:0002269 | EFO:1001463 |
1 further indication record had no mapped disease name (EFO/MeSH-only) or were duplicates, and are omitted.
Clinical trials
Total trials: 107.
Phase distribution
| Phase | Trials |
|---|---|
| Not specified | 86 |
| PHASE2 | 8 |
| EARLY_PHASE1 | 5 |
| PHASE4 | 3 |
| PHASE3 | 3 |
| PHASE1/PHASE2 | 2 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT04698330 | PHASE4 | NOT_YET_RECRUITING | Effects Of Berberine Plus Inulin On Diabetes Care in Patients With LADA |
| NCT03117322 | PHASE4 | COMPLETED | Synbiotic, Prebiotics and Probiotics in Children With Cerebral Palsy and Constipation |
| NCT04118010 | PHASE4 | COMPLETED | Vitamin D and Prebiotics for Intestinal Health in Cystic Fibrosis |
| NCT00826137 | PHASE3 | COMPLETED | Preventing Childhood Antibiotic-associated Diarrhea by Prebiotics |
| NCT02773927 | PHASE3 | COMPLETED | Combination of Metformin/Inulin vs Inulin on Adiponectin in Metabolic Syndrome |
| NCT02778776 | PHASE3 | COMPLETED | Combination of Metformine/Inulin Versus Metformin on Prostate Benign Hyperplasia in Metabolic Syndrome |
| NCT05946083 | PHASE2 | RECRUITING | The Brain, the Bug, and the Binge: the Interplay Between Binge Drinking, Gut Microbiota, and Brain Functioning |
| NCT06372249 | PHASE2 | RECRUITING | A Clinical Trial of Soluble Fiber for Asthma |
| NCT06866262 | PHASE1/PHASE2 | RECRUITING | Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell Cancer, ICON Trial |
| NCT07189585 | PHASE2 | NOT_YET_RECRUITING | Inulin Supplementation for Reducing Inflammation and Knee Pain in Older Adults With Osteoarthritis |
| NCT07300553 | PHASE2 | RECRUITING | Impact Of The Gut Microbiota On Host Cells Energy Metabolism in Health And In Inflammatory Bowel Disease |
| NCT00319007 | PHASE2 | UNKNOWN | Influence of Sulindac and Probiotics on the Development of Pouch Adenomas in Patients With Familial Adenomatous Polyposis |
| NCT00335504 | PHASE2 | COMPLETED | Atorvastatin Calcium, Oligofructose-Enriched Inulin, or Sulindac in Preventing Cancer in Patients at Increased Risk of Developing Colorectal Neoplasia |
| NCT01130792 | PHASE1/PHASE2 | COMPLETED | Probiotics for Infectious Diarrhea in Children in South India |
| NCT01505023 | PHASE2 | COMPLETED | Partial Meal Replacement and Inulin in Obese Women |
| NCT03865706 | PHASE2 | COMPLETED | Inulin for Infections in the Intensive Care Unit |
| NCT01233024 | EARLY_PHASE1 | COMPLETED | Satiety Response of Four Dietary Fibers |
| NCT02718885 | EARLY_PHASE1 | COMPLETED | Gut Microbiome Mediated Effects of Inulin Supplementation on Mineral and Bone Metabolism in Hemodialysis Patients |
| NCT04543877 | EARLY_PHASE1 | COMPLETED | WHNRC (Western Human Nutrition Research Center) Fiber Intervention Study |
| NCT05277090 | EARLY_PHASE1 | UNKNOWN | Bowel Preparation May Lead to a Higher Feasibility of Intestinal Infection |
| NCT06347198 | EARLY_PHASE1 | UNKNOWN | Oral Inulin in Combination With Fruquintinib Plus Sintilimab as Third- or Further-line Treatment in Metastatic Colorectal Cancer |
| NCT03995342 | Not specified | ENROLLING_BY_INVITATION | The Correlation and Intervention of Intestinal Flora and Frailty in the Elderly |
| NCT05071131 | Not specified | RECRUITING | Effect of Inulin on Gut Microbiota and Gut Barrier in Chronic Kidney Disease |
| NCT05353504 | Not specified | RECRUITING | Impact of Microbiome-changing Interventions on Food Decision-making |
| NCT05860322 | Not specified | NOT_YET_RECRUITING | The Effect of Inulin Supplementation on Colorectal Surgery Outcomes |
| NCT06420401 | Not specified | RECRUITING | Prebiotics and the Management of Hyperuricemia |
| NCT06433037 | Not specified | ACTIVE_NOT_RECRUITING | Gut-brain Health Effects of PREbiotics in Older Adults With Suspected COgnitive DEcline |
| NCT06448663 | Not specified | RECRUITING | Targeting the Gut to Improve Seizure Control in CDKL5 Deficiency Disorder (CDD) |
| NCT06494137 | Not specified | NOT_YET_RECRUITING | Effect of Pre-dosing With Methylcellulose or Psyllium on Colonic Fermentation of Inulin |
| NCT06528041 | Not specified | RECRUITING | Impact of Native Chicory Inulin on Change and Persistence of Gut Microbiota |
| NCT06541938 | Not specified | RECRUITING | AIRE-2 Device for Study of Breath Analysis in IBD |
| NCT06551961 | Not specified | RECRUITING | Effect of Chronic Feeding of Inulin And Methylcellulose on Colonic Fermentation |
| NCT06607523 | Not specified | RECRUITING | The Gut-Brain Axis During Neurorehabilitation; Prebiotic Treatment to Alter the Gut Microbiome and Neurologic Symptoms |
| NCT06668922 | Not specified | RECRUITING | Irritable Bowel Syndrome and Control Volunteers: Diet Challenge |
| NCT06738550 | Not specified | ENROLLING_BY_INVITATION | Effect of Agave Inulin on Constipation and Quality of Life in Peritoneal Dialysis Patients. |
| NCT07095426 | Not specified | RECRUITING | Impact of Supplemental Fiber on Gut and Vascular Health Related in Obesity Phenotypes |
| NCT07487623 | Not specified | RECRUITING | Evaluation of the Hepatoprotective Effects of a Nutritional Supplement in Patients With Liver Disease Secondary to Chronic Hepatitis C Virus Infection (RESQUETI Study). |
| NCT07525180 | Not specified | NOT_YET_RECRUITING | Comparing Prebiotic Fiber Supplements for Gut Health and Digestive Comfort |
| NCT07537192 | Not specified | NOT_YET_RECRUITING | Inulin-Spirulina Co-intervention for Insomnia Disorder |
| NCT07559227 | Not specified | RECRUITING | Gut, Immune, and Vascular Health in Metabolically Healthy Obesity |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
- Diseases: metabolic syndrome X