Licorice
drugOn this page
Also known as B2048FEMA NO. 2628FEMA NO. 2629FEMA NO. 2630Glycyrrhiza glabra extractGlycyrrhiza glabra rhizomeGlycyrrhiza glabra rootGlycyrrhiza glabra root powderGlycyrrhiza glabra root with rhizomeNDI 329
Summary
Licorice (CHEMBL2109060) is a phase-3 clinical-stage unknown; indicated across 6 conditions including dental caries and lichen planus, oral.
At a glance
- Status: Max clinical phase 3 (not approved)
- Modality: Unknown
- Indications: 6 conditions
- Clinical trials: 11
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL2109060 |
| Name | Licorice |
| Type | Unknown |
| Max phase | 3 |
Also known as: B2048, FEMA NO. 2628, FEMA NO. 2629, FEMA NO. 2630, Glycyrrhiza glabra extract, Glycyrrhiza glabra rhizome, Glycyrrhiza glabra root, Glycyrrhiza glabra root powder, Glycyrrhiza glabra root with rhizome, Licorice, NDI 329, LICORICE
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
6 indications (0 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).
| Indication | Trial phase | MONDO | EFO |
|---|---|---|---|
| dental caries | 2 | MONDO:0005276 | EFO:0003819 |
| lichen planus, oral | 2 | MONDO:0043923 | EFO:0008517 |
| inborn error of immunity | 2 | MONDO:0003778 | HP:0002721 |
| severe acute respiratory syndrome | 2 | MONDO:0005091 | MONDO:0100096 |
| stroke disorder | 1 | MONDO:0005098 | EFO:0000712 |
| mucositis | 1 | MONDO:0020579 | EFO:1001898 |
Clinical trials
Total trials: 11.
Phase distribution
| Phase | Trials |
|---|---|
| Not specified | 7 |
| PHASE4 | 1 |
| PHASE2/PHASE3 | 1 |
| PHASE2 | 1 |
| PHASE1 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT00605202 | PHASE4 | COMPLETED | Effect of Licorice and Hydrochlorothiazide on Plasma Potassium |
| NCT03684993 | PHASE2/PHASE3 | COMPLETED | Caries Prevention and Side Effects of Gum Arabic and Licorice Extracts Versus Chlorhexidine in High Caries Risk Patients |
| NCT02453503 | PHASE2 | COMPLETED | Comparison of Triamcinolone Acetonide Mucoadhesive Film and Licorice Mucoadhesive Film Effect on Lichen Planus |
| NCT03948243 | PHASE1 | COMPLETED | Licorice Botanical Dietary Supplements - Metabolism and Safety in Women |
| NCT01444703 | Not specified | COMPLETED | Comparison of Licorice Versus Sugar-water Gargle for Prevention of Postoperative Sore Throat and Postextubation Coughing |
| NCT02968823 | Not specified | COMPLETED | Licorice Versus Sugar-water Gargling for Pain in Patients Recovering From Ear-Nose-Throat and Maxilla-Facial Surgery |
| NCT03550651 | Not specified | COMPLETED | Evaluation of Antiplaque Efficacy of Licorice Extract Mouthrinse & HSS and Their Comparison With EO & CHX Mouthrinse |
| NCT03763578 | Not specified | COMPLETED | Dental Caries Prevention by a Natural Product |
| NCT04487964 | Not specified | COMPLETED | Complementary Intervention for COVID-19 |
| NCT05661721 | Not specified | COMPLETED | Licorice and Home Blood Pressure |
| NCT06019598 | Not specified | COMPLETED | Licorice and Home Blood Pressure, Additional Study |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.