Lotrafilcon B
drugOn this page
Also known as Air optix aqua
Summary
Lotrafilcon B (CHEMBL2108620) is a phase-3 clinical-stage small molecule.
At a glance
- Status: Max clinical phase 3 (not approved)
- Modality: Small molecule
- Clinical trials: 27
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL2108620 |
| Name | Lotrafilcon B |
| Type | Small molecule |
| Max phase | 3 |
Also known as: Air optix aqua, Lotrafilcon b, LOTRAFILCON B
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
0 indications (0 at ChEMBL trial phase 4).
Clinical trials
Total trials: 27.
Phase distribution
| Phase | Trials |
|---|---|
| Not specified | 26 |
| PHASE4 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT03881670 | PHASE4 | COMPLETED | On-Eye Optical Quality of Lotrafilcon B Lenses Over 12 Hours |
| NCT00584831 | Not specified | COMPLETED | Effect of Eye Movement on Toric Lens Orientation and Visual Acuity |
| NCT00762788 | Not specified | COMPLETED | Clinical Trial of Several Contact Lenses in Extended Wear |
| NCT00909792 | Not specified | COMPLETED | Clinical Evaluation of Two New Silicone Hydrogel Multifocal Products |
| NCT00912028 | Not specified | COMPLETED | Clinical Performance Comparison of Several Different Contact Lenses |
| NCT00975585 | Not specified | COMPLETED | Clinical Performance Comparison of Two Contact Lenses |
| NCT01010555 | Not specified | COMPLETED | In-vivo Wettability Grading and Assessment Study |
| NCT01100411 | Not specified | COMPLETED | Changes in Invitro and ex Vivo Lens Metrology With Daily Wear Contact Lenses |
| NCT01131130 | Not specified | COMPLETED | Feasibility of a New Silicone Hydrogel Lens |
| NCT01244516 | Not specified | COMPLETED | Multi-Center 2-Week Clinical Evaluation of Three Silicone Hydrogel Contact Lenses |
| NCT01309880 | Not specified | COMPLETED | Evaluation of a New Silicone Hydrogel Contact Lens |
| NCT01392950 | Not specified | COMPLETED | Clinical Study of Clariti Monthly Contact Lens |
| NCT01433549 | Not specified | COMPLETED | Lens Wear Schedules and End-of-Day Comfort |
| NCT01526902 | Not specified | COMPLETED | Proclear 1-D Multifocal Nondispensing Study |
| NCT01583868 | Not specified | COMPLETED | A Study to Evaluate the Product Feasibility of Two New Silicone Hydrogel Contact Lenses |
| NCT01763047 | Not specified | COMPLETED | Evaluation of the Performance of Investigational Contact Lenses in a Presbyopic Population |
| NCT01952665 | Not specified | COMPLETED | A Multi-Center Study Comparing the Clinical Performance of Two Silicone Hydrogel Lenses Over 1 Month of Daily Wear |
| NCT01965288 | Not specified | COMPLETED | Clinical Performance of Biofinity Toric Versus Air Optix for Astigmatism |
| NCT01996787 | Not specified | COMPLETED | Clinical Study of Visibility Tinted Clariti Contact Lens |
| NCT02212301 | Not specified | COMPLETED | Comparison of Two Marketed Lenses in a Controlled Environment |
| NCT02214797 | Not specified | COMPLETED | Dispensing Study to Assess Visual Performance of Prototype Contact Lenses |
| NCT02223754 | Not specified | COMPLETED | Evaluation of an Investigational Multifocal Lens |
| NCT02328937 | Not specified | COMPLETED | Central Corneal Swelling With Silicone Hydrogel Materials |
| NCT02349438 | Not specified | COMPLETED | Assessment of Contact Lens Wettability Using Wavefront Aberrometry |
| NCT02394808 | Not specified | COMPLETED | 2-week Evaluation of Marketed Silicone Hydrogel Contact Lenses in Indian Population |
| NCT02716298 | Not specified | COMPLETED | A Dispensing Clinical of Fanfilcon A Lens Against Lotrafilcon B Lens Over 1 Month Wear Per Lens |
| NCT02815735 | Not specified | COMPLETED | Multi-Centre Clinical Evaluation of Two Reusable Soft Contact Lenses |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.