Methylcellulose
drugOn this page
Also known as Benecel mc a15cCelevacCelluconCellulose methyl etherCitrucelCologelE-461FEMA NO. 2696INS NO.461INS-461MethycelluloseMethyl ether of celluloseMethylcellulose (1500 cps)Methylcellulose (1500 mpa.s)Methylcellulose 1500unspecifiedMethylcellulosesMethylcellulosumMetilcelulosa
Summary
Methylcellulose (CHEMBL2109198) is an approved unknown (ATC A06AC06); indicated across 3 conditions including constipation disorder and chronic kidney disease.
At a glance
- Status: Approved (max clinical phase 4)
- Modality: Unknown
- ATC class: A06AC06
- Indications: 3 conditions
- Clinical trials: 13
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL2109198 |
| Name | Methylcellulose |
| Type | Unknown |
| Max phase | 4 |
| ATC | A06AC06 |
Also known as: Benecel mc a15c, Celevac, Cellucon, Cellulose methyl ether, Citrucel, Cologel, E-461, FEMA NO. 2696, INS NO.461, INS-461, Methycellulose, Methyl ether of cellulose
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
3 indications (1 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).
| Indication | Trial phase | MONDO | EFO |
|---|---|---|---|
| constipation disorder | 4 | MONDO:0002203 | HP:0002019 |
| chronic kidney disease | 2 | MONDO:0005300 | EFO:0003884 |
| cataract | 1 | MONDO:0005129 | MONDO:0005129 |
Clinical trials
Total trials: 13.
Phase distribution
| Phase | Trials |
|---|---|
| PHASE4 | 4 |
| Not specified | 4 |
| PHASE2 | 3 |
| PHASE3 | 2 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT00865540 | PHASE4 | UNKNOWN | Effect of Anti-inflammatory Topical Prednisolone, Nepafenac and Ketorolac in Intra-operative Mydriasis in Facetectomies |
| NCT00934973 | PHASE4 | COMPLETED | Management of Irritable Bowel Syndrome in Primary Care (MIBS Trial) |
| NCT03452891 | PHASE4 | COMPLETED | Effect of Locally-Applied Simvastatin on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients |
| NCT04668859 | PHASE4 | TERMINATED | Midodrine as Novel Treatment of Post-Cardiopulmonary Bypass Vasoplegic Syndrome |
| NCT06514586 | PHASE3 | NOT_YET_RECRUITING | The Efficacy of Topical Vaginal Oxytocin Gel in Postmenopausal Women With Vulvovaginal Atrophy |
| NCT01497951 | PHASE3 | COMPLETED | Photodynamic Therapy for Oral Precursor Lesions |
| NCT01528800 | PHASE2 | COMPLETED | Vitamin K to Attenuate Coronary Artery Calcification in Hemodialysis Patients |
| NCT01532401 | PHASE2 | COMPLETED | Oral Sodium Blood Pressure in Normal Weight, Overweight and Obese Volunteers |
| NCT03484507 | PHASE2 | COMPLETED | Parasitic Ulcer Treatment Trial Pilot |
| NCT06551961 | Not specified | RECRUITING | Effect of Chronic Feeding of Inulin And Methylcellulose on Colonic Fermentation |
| NCT05911347 | Not specified | COMPLETED | Effect of Modified Cellulose on Colonic Fermentation of Inulin |
| NCT06291272 | Not specified | COMPLETED | Effect of Methylcellulose or Psyllium on Fermentation of inUlin Assessed USing MRI |
| NCT06551948 | Not specified | COMPLETED | Effect of MethylceIlulose or Psyllium on Fermentation of Inulin Assessed Using a Gas Sensing Capsule |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
- Diseases: constipation disorder