Microcrystalline Cellulose
drug drugOn this page
Also known as Avicel phCellulose microcrystallineCellulosemicrocrystallinePharmacel
Summary
Microcrystalline Cellulose (CHEMBL4297557) is a phase-3 clinical-stage unknown; indicated across 17 conditions including long covid-19 and gastroenteritis.
At a glance
- Status: Max clinical phase 3 (not approved)
- Modality: Unknown
- Indications: 17 conditions
- Clinical trials: 48
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL4297557 |
| Name | Microcrystalline Cellulose |
| Type | Unknown |
| Max phase | 3 |
Also known as: Avicel ph, Cellulose microcrystalline, Cellulose, microcrystalline, Microcrystalline cellulose, Pharmacel, MICROCRYSTALLINE CELLULOSE
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
12 diseases in clinical trials (phase 1–3, investigational — not approved indications). Highest ChEMBL trial phase per disease; a non-cancer approved use is occasionally logged at phase 3 here.
| Disease (in trials) | Phase | MONDO | EFO |
|---|---|---|---|
| long COVID-19 | 3 | MONDO:0100233 | MONDO:0100233 |
| gastroenteritis | 2 | MONDO:0002269 | EFO:1001463 |
| hypertensive disorder | 2 | MONDO:0005044 | EFO:0000537 |
| osteoarthritis, knee | 2 | MONDO:0005416 | EFO:0004616 |
| type 2 diabetes mellitus | 2 | MONDO:0005148 | MONDO:0005148 |
| major depressive disorder | 2 | MONDO:0002009 | MONDO:0002009 |
| severe acute respiratory syndrome | 2 | MONDO:0005091 | MONDO:0100096 |
| glioblastoma | 1 | MONDO:0018177 | EFO:0000519 |
| depressive disorder | 1 | MONDO:0002050 | MONDO:0002050 |
| Lewy body dementia | 1 | MONDO:0007488 | EFO:0006792 |
| sickle cell disease | 1 | MONDO:0011382 | MONDO:0011382 |
| type 1 diabetes mellitus | 1 | MONDO:0005147 | MONDO:0005147 |
4 further indication records had no mapped disease name (EFO/MeSH-only) or were duplicates, and are omitted.
Clinical trials
Total trials: 48.
Phase distribution
| Phase | Trials |
|---|---|
| Not specified | 25 |
| PHASE2 | 6 |
| PHASE4 | 5 |
| PHASE1 | 5 |
| PHASE3 | 3 |
| PHASE2/PHASE3 | 2 |
| EARLY_PHASE1 | 2 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT05363514 | PHASE4 | NOT_YET_RECRUITING | Low Dose Naltrexone Use in Patients With POTS |
| NCT01251991 | PHASE4 | COMPLETED | Cholesterol Lowering Treatment With Psyllium Husks and Isolated Soy Protein in Hypercholesterolemia |
| NCT03246724 | PHASE4 | COMPLETED | Oral Versus Intravenous Sedation for Ocular Procedures |
| NCT05810116 | PHASE4 | COMPLETED | Effectiveness of PEA Compared to Placebo on Acute Menstrual Pain |
| NCT05821543 | PHASE4 | COMPLETED | Efficacy and Safety of Sibutramin-containing Drugs in Patient With Alimentary Obesity |
| NCT07149649 | PHASE2/PHASE3 | NOT_YET_RECRUITING | Magnesium Supplementation in Advanced Non-small Cell Lung Cancer (NSCLC) |
| NCT03085680 | PHASE2/PHASE3 | COMPLETED | Curcumin and Function in Older Adults |
| NCT04955327 | PHASE3 | COMPLETED | To Compare the Efficacy and Tolerability of A. Paniculata/A. Chilensis in Individuals With URTI |
| NCT05795816 | PHASE3 | COMPLETED | Effectiveness of Testofen Compared to Placebo on Long COVID Symptoms |
| NCT05825209 | PHASE3 | COMPLETED | Effectiveness of Food-grown Magnesium on Sleep Quality/Quantity |
| NCT06072898 | PHASE2 | RECRUITING | A Randomized Neuroimaging Trial of Psilocybin in Depression |
| NCT00784511 | PHASE2 | COMPLETED | Vitamin D, Glucose Control and Insulin Sensitivity in African-Americans |
| NCT01525758 | PHASE2 | UNKNOWN | Study of SI000413 in Knee Osteoarthritis Patients |
| NCT01690676 | PHASE2 | COMPLETED | Effect of an Apple Polyphenol Extract on Brachial Artery Flow-mediated Vasodilatory Function |
| NCT02324153 | PHASE2 | COMPLETED | Ramelteon in the Prevention of Post-operative Delirium |
| NCT06012565 | PHASE2 | TERMINATED | KAND567 Versus Placebo in Subjects Hospitalized With COVID-19 |
| NCT01520649 | PHASE1 | COMPLETED | Multiple-Dose Pharmacokinetics (PK), and Pharmacodynamic (PD) Effect of NSI-189 Phosphate in Depression Patient Subjects |
| NCT03340220 | PHASE1 | COMPLETED | Safety, Tolerability, and Pharmacokinetics (PK) of Single and Multiple Ascending Oral Doses of XEN1101. |
| NCT03468725 | PHASE1 | COMPLETED | Safety, Tolerability, Pharmacokinetics and Effects on Transcranial Magnetic Stimulation of Oral Doses of XEN1101 |
| NCT03978156 | PHASE1 | TERMINATED | Dronabinol for Pain and Inflammation in Adults Living With Sickle Cell Disease |
| NCT04963855 | PHASE1 | UNKNOWN | A Phase I Study of GT300 in Healthy Subjects |
| NCT01582113 | EARLY_PHASE1 | COMPLETED | Cognizin Citicoline Dosing in a Healthy Adolescent Male Population |
| NCT04021550 | EARLY_PHASE1 | WITHDRAWN | Improving 24-hour Blood Pressure in Obstructive Sleep Apnea |
| NCT03990909 | Not specified | RECRUITING | Pilot Study of BCAA on Sleep |
| NCT06515210 | Not specified | RECRUITING | Personalized Anti-Inflammatory Fibres in Ulcerative Colitis |
| NCT06518343 | Not specified | ACTIVE_NOT_RECRUITING | Trimethylamine N-oxide Effects of a Pomegranate Supplement Simultaneously With Carnitine (TESSA) |
| NCT07093463 | Not specified | RECRUITING | Colon-delivered Riboflavin and Gut Microbiota Composition |
| NCT07341789 | Not specified | ENROLLING_BY_INVITATION | Effects of Vitamin B12 and Natural Orange Extract, and Their Combination on Physical and Mental Performance |
| NCT07397273 | Not specified | NOT_YET_RECRUITING | Acute Effects of Alpha-glycerylphosphorylcholine (A-GPC) on Lower Body Muscular Performance. |
| NCT07471659 | Not specified | RECRUITING | Effect of Daily Humiome® Post LB Intake on Wellbeing in Older Individuals With Moderate Stress Levels |
| NCT07611305 | Not specified | NOT_YET_RECRUITING | ProGo Menopause Wellbeing Study |
| NCT00732732 | Not specified | TERMINATED | A Controlled Trial of Plantain Powder in Infantile Diarrhea |
| NCT01515917 | Not specified | WITHDRAWN | Citicoline and Omega-3 Fatty Acid Effects in Veterans With Traumatic Brain Injury (TBI) |
| NCT01549600 | Not specified | COMPLETED | Comparison of Psyllium and Microcrystalline Cellulose on Glycemic Measures in Subjects With Impaired Fasting Glucose |
| NCT03764423 | Not specified | COMPLETED | Health Effects of Salmon Fishmeal in Humans |
| NCT03832439 | Not specified | COMPLETED | Probiotic Supplementation on Weight Loss |
| NCT03982290 | Not specified | UNKNOWN | Psychophysiological Effects of Lactobacillus Plantarum PS128 in Preschool Children With Autism Spectrum Disorder |
| NCT04048616 | Not specified | COMPLETED | Impact of Protein and Alkali Supplementation on Skeletal Muscle in Older Adults |
| NCT04733924 | Not specified | COMPLETED | Efficacy and Tolerability of Sensoril® in Improving Immunity and Thereby Reducing Incidence of Upper Respiratory Tract Infections |
| NCT04754464 | Not specified | COMPLETED | Clinical Study on the Effect of a Synbiotic on Body Fat Mass |
| NCT04950296 | Not specified | COMPLETED | To Study the Efficacy and Safety of L. Plantarum UALp-05TM in Diarrhea- Predominant-irritable Bowel Syndrome |
| NCT05474586 | Not specified | COMPLETED | To Evaluate the Efficacy and Safety of Collavant n2 in Individuals With Osteoarthritis of the Knee |
| NCT05517122 | Not specified | COMPLETED | Effect of Oral NAD+ Precursors Administration on Blood NAD+ Concentration in Healthy Adults |
| NCT05564676 | Not specified | COMPLETED | Flaxseed Oil and Pomegranate Extract on Inflammation, Lipid Profile and Nutritional Status of Hemodialysis Patients |
| NCT05621395 | Not specified | COMPLETED | To Study the Effect of Investigational Product on Fatigue and Cardiorespiratory Fitness in Healthy Adults. |
| NCT06348212 | Not specified | UNKNOWN | Effect of Probiotic Strain Lactobacillus Paracasei PS23 on Brain Fog in People With Long COVID |
| NCT06535204 | Not specified | COMPLETED | Effects of Anthriscus Sylvestris Leaves on Mild Knee Osteoarthritis |
| NCT07019415 | Not specified | COMPLETED | Efect Supplementation Vitamin D in Diabetes Mellitus Type 2 |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).