Microcrystalline Cellulose

drug
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Also known as Avicel phCellulose microcrystallineCellulosemicrocrystallinePharmacel

Summary

Microcrystalline Cellulose (CHEMBL4297557) is a phase-3 clinical-stage unknown; indicated across 17 conditions including long covid-19 and gastroenteritis.

At a glance

  • Status: Max clinical phase 3 (not approved)
  • Modality: Unknown
  • Indications: 17 conditions
  • Clinical trials: 48

Identifiers

Drug identity and classification

FieldValue
ChEMBL IDCHEMBL4297557
NameMicrocrystalline Cellulose
TypeUnknown
Max phase3

Also known as: Avicel ph, Cellulose microcrystalline, Cellulose, microcrystalline, Microcrystalline cellulose, Pharmacel, MICROCRYSTALLINE CELLULOSE

Targets

Targets

No target linkage available.

Bioactivity

No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).

Target pathways

No target-pathway data for this drug (no mapped target genes).

Indications & clinical

Indications

12 diseases in clinical trials (phase 1–3, investigational — not approved indications). Highest ChEMBL trial phase per disease; a non-cancer approved use is occasionally logged at phase 3 here.

Disease (in trials)PhaseMONDOEFO
long COVID-193MONDO:0100233MONDO:0100233
gastroenteritis2MONDO:0002269EFO:1001463
hypertensive disorder2MONDO:0005044EFO:0000537
osteoarthritis, knee2MONDO:0005416EFO:0004616
type 2 diabetes mellitus2MONDO:0005148MONDO:0005148
major depressive disorder2MONDO:0002009MONDO:0002009
severe acute respiratory syndrome2MONDO:0005091MONDO:0100096
glioblastoma1MONDO:0018177EFO:0000519
depressive disorder1MONDO:0002050MONDO:0002050
Lewy body dementia1MONDO:0007488EFO:0006792
sickle cell disease1MONDO:0011382MONDO:0011382
type 1 diabetes mellitus1MONDO:0005147MONDO:0005147

4 further indication records had no mapped disease name (EFO/MeSH-only) or were duplicates, and are omitted.

Clinical trials

Total trials: 48.

Phase distribution

PhaseTrials
Not specified25
PHASE26
PHASE45
PHASE15
PHASE33
PHASE2/PHASE32
EARLY_PHASE12

Top trials by phase / activity

NCTPhaseStatusTitle
NCT05363514PHASE4NOT_YET_RECRUITINGLow Dose Naltrexone Use in Patients With POTS
NCT01251991PHASE4COMPLETEDCholesterol Lowering Treatment With Psyllium Husks and Isolated Soy Protein in Hypercholesterolemia
NCT03246724PHASE4COMPLETEDOral Versus Intravenous Sedation for Ocular Procedures
NCT05810116PHASE4COMPLETEDEffectiveness of PEA Compared to Placebo on Acute Menstrual Pain
NCT05821543PHASE4COMPLETEDEfficacy and Safety of Sibutramin-containing Drugs in Patient With Alimentary Obesity
NCT07149649PHASE2/PHASE3NOT_YET_RECRUITINGMagnesium Supplementation in Advanced Non-small Cell Lung Cancer (NSCLC)
NCT03085680PHASE2/PHASE3COMPLETEDCurcumin and Function in Older Adults
NCT04955327PHASE3COMPLETEDTo Compare the Efficacy and Tolerability of A. Paniculata/A. Chilensis in Individuals With URTI
NCT05795816PHASE3COMPLETEDEffectiveness of Testofen Compared to Placebo on Long COVID Symptoms
NCT05825209PHASE3COMPLETEDEffectiveness of Food-grown Magnesium on Sleep Quality/Quantity
NCT06072898PHASE2RECRUITINGA Randomized Neuroimaging Trial of Psilocybin in Depression
NCT00784511PHASE2COMPLETEDVitamin D, Glucose Control and Insulin Sensitivity in African-Americans
NCT01525758PHASE2UNKNOWNStudy of SI000413 in Knee Osteoarthritis Patients
NCT01690676PHASE2COMPLETEDEffect of an Apple Polyphenol Extract on Brachial Artery Flow-mediated Vasodilatory Function
NCT02324153PHASE2COMPLETEDRamelteon in the Prevention of Post-operative Delirium
NCT06012565PHASE2TERMINATEDKAND567 Versus Placebo in Subjects Hospitalized With COVID-19
NCT01520649PHASE1COMPLETEDMultiple-Dose Pharmacokinetics (PK), and Pharmacodynamic (PD) Effect of NSI-189 Phosphate in Depression Patient Subjects
NCT03340220PHASE1COMPLETEDSafety, Tolerability, and Pharmacokinetics (PK) of Single and Multiple Ascending Oral Doses of XEN1101.
NCT03468725PHASE1COMPLETEDSafety, Tolerability, Pharmacokinetics and Effects on Transcranial Magnetic Stimulation of Oral Doses of XEN1101
NCT03978156PHASE1TERMINATEDDronabinol for Pain and Inflammation in Adults Living With Sickle Cell Disease
NCT04963855PHASE1UNKNOWNA Phase I Study of GT300 in Healthy Subjects
NCT01582113EARLY_PHASE1COMPLETEDCognizin Citicoline Dosing in a Healthy Adolescent Male Population
NCT04021550EARLY_PHASE1WITHDRAWNImproving 24-hour Blood Pressure in Obstructive Sleep Apnea
NCT03990909Not specifiedRECRUITINGPilot Study of BCAA on Sleep
NCT06515210Not specifiedRECRUITINGPersonalized Anti-Inflammatory Fibres in Ulcerative Colitis
NCT06518343Not specifiedACTIVE_NOT_RECRUITINGTrimethylamine N-oxide Effects of a Pomegranate Supplement Simultaneously With Carnitine (TESSA)
NCT07093463Not specifiedRECRUITINGColon-delivered Riboflavin and Gut Microbiota Composition
NCT07341789Not specifiedENROLLING_BY_INVITATIONEffects of Vitamin B12 and Natural Orange Extract, and Their Combination on Physical and Mental Performance
NCT07397273Not specifiedNOT_YET_RECRUITINGAcute Effects of Alpha-glycerylphosphorylcholine (A-GPC) on Lower Body Muscular Performance.
NCT07471659Not specifiedRECRUITINGEffect of Daily Humiome® Post LB Intake on Wellbeing in Older Individuals With Moderate Stress Levels
NCT07611305Not specifiedNOT_YET_RECRUITINGProGo Menopause Wellbeing Study
NCT00732732Not specifiedTERMINATEDA Controlled Trial of Plantain Powder in Infantile Diarrhea
NCT01515917Not specifiedWITHDRAWNCiticoline and Omega-3 Fatty Acid Effects in Veterans With Traumatic Brain Injury (TBI)
NCT01549600Not specifiedCOMPLETEDComparison of Psyllium and Microcrystalline Cellulose on Glycemic Measures in Subjects With Impaired Fasting Glucose
NCT03764423Not specifiedCOMPLETEDHealth Effects of Salmon Fishmeal in Humans
NCT03832439Not specifiedCOMPLETEDProbiotic Supplementation on Weight Loss
NCT03982290Not specifiedUNKNOWNPsychophysiological Effects of Lactobacillus Plantarum PS128 in Preschool Children With Autism Spectrum Disorder
NCT04048616Not specifiedCOMPLETEDImpact of Protein and Alkali Supplementation on Skeletal Muscle in Older Adults
NCT04733924Not specifiedCOMPLETEDEfficacy and Tolerability of Sensoril® in Improving Immunity and Thereby Reducing Incidence of Upper Respiratory Tract Infections
NCT04754464Not specifiedCOMPLETEDClinical Study on the Effect of a Synbiotic on Body Fat Mass
NCT04950296Not specifiedCOMPLETEDTo Study the Efficacy and Safety of L. Plantarum UALp-05TM in Diarrhea- Predominant-irritable Bowel Syndrome
NCT05474586Not specifiedCOMPLETEDTo Evaluate the Efficacy and Safety of Collavant n2 in Individuals With Osteoarthritis of the Knee
NCT05517122Not specifiedCOMPLETEDEffect of Oral NAD+ Precursors Administration on Blood NAD+ Concentration in Healthy Adults
NCT05564676Not specifiedCOMPLETEDFlaxseed Oil and Pomegranate Extract on Inflammation, Lipid Profile and Nutritional Status of Hemodialysis Patients
NCT05621395Not specifiedCOMPLETEDTo Study the Effect of Investigational Product on Fatigue and Cardiorespiratory Fitness in Healthy Adults.
NCT06348212Not specifiedUNKNOWNEffect of Probiotic Strain Lactobacillus Paracasei PS23 on Brain Fog in People With Long COVID
NCT06535204Not specifiedCOMPLETEDEffects of Anthriscus Sylvestris Leaves on Mild Knee Osteoarthritis
NCT07019415Not specifiedCOMPLETEDEfect Supplementation Vitamin D in Diabetes Mellitus Type 2

Clinical evidence (CIViC)

No CIViC predictive evidence (expected for non-precision-medicine drugs).

Pharmacology

Pharmacogenomics

No PharmGKB pharmacogenomic data curated for this drug.

No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).