Neisseria Meningitidis Factor H Binding Protein
drugOn this page
Also known as Trumenba
Summary
Neisseria Meningitidis Factor H Binding Protein (CHEMBL6068499) is an approved vaccine component; indicated across 3 conditions including infectious meningitis and meningococcal meningitis.
At a glance
- Status: Approved (max clinical phase 4)
- Modality: Vaccine component
- Indications: 3 conditions
- Clinical trials: 4
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL6068499 |
| Name | Neisseria Meningitidis Factor H Binding Protein |
| Type | Vaccine component |
| Max phase | 4 |
Also known as: Trumenba
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
3 indications (3 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).
| Indication | Trial phase | MONDO | EFO |
|---|---|---|---|
| infectious meningitis | 4 | MONDO:0004796 | EFO:0000584 |
| meningococcal meningitis | 4 | MONDO:0018059 | EFO:1001040 |
1 further indication record had no mapped disease name (EFO/MeSH-only) or were duplicates, and are omitted.
Clinical trials
Total trials: 4.
Phase distribution
| Phase | Trials |
|---|---|
| PHASE4 | 2 |
| PHASE3 | 1 |
| Not specified | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT07197762 | PHASE4 | RECRUITING | MenB-FHbp or MenACWY-TT/MenB-FHbp Vaccine in MenB-4C Primed Young Adults |
| NCT04893811 | PHASE4 | COMPLETED | Trial to Describe the Safety, Tolerability, and Immunogenicity of Trumenba When Administered to Immunocompromised Participants ≥10 Years of Age |
| NCT04440163 | PHASE3 | COMPLETED | MenABCWY Noninferiority Study in Healthy Participants ≥10 to <26 Years of Age |
| NCT05873751 | Not specified | COMPLETED | A Study to Learn About How Trumenba Vaccine Shots Work Against Gonorrhea Infection in Teenagers and Young Adults in the United States. |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
- Diseases: infectious meningitis, meningococcal meningitis