Neisseria Meningitidis Factor H Binding Protein

drug
On this page

Also known as Trumenba

Summary

Neisseria Meningitidis Factor H Binding Protein (CHEMBL6068499) is an approved vaccine component; indicated across 3 conditions including infectious meningitis and meningococcal meningitis.

At a glance

  • Status: Approved (max clinical phase 4)
  • Modality: Vaccine component
  • Indications: 3 conditions
  • Clinical trials: 4

Identifiers

Drug identity and classification

FieldValue
ChEMBL IDCHEMBL6068499
NameNeisseria Meningitidis Factor H Binding Protein
TypeVaccine component
Max phase4

Also known as: Trumenba

Targets

Targets

No target linkage available.

Bioactivity

No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).

Target pathways

No target-pathway data for this drug (no mapped target genes).

Indications & clinical

Indications

3 indications (3 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).

IndicationTrial phaseMONDOEFO
infectious meningitis4MONDO:0004796EFO:0000584
meningococcal meningitis4MONDO:0018059EFO:1001040

1 further indication record had no mapped disease name (EFO/MeSH-only) or were duplicates, and are omitted.

Clinical trials

Total trials: 4.

Phase distribution

PhaseTrials
PHASE42
PHASE31
Not specified1

Top trials by phase / activity

NCTPhaseStatusTitle
NCT07197762PHASE4RECRUITINGMenB-FHbp or MenACWY-TT/MenB-FHbp Vaccine in MenB-4C Primed Young Adults
NCT04893811PHASE4COMPLETEDTrial to Describe the Safety, Tolerability, and Immunogenicity of Trumenba When Administered to Immunocompromised Participants ≥10 Years of Age
NCT04440163PHASE3COMPLETEDMenABCWY Noninferiority Study in Healthy Participants ≥10 to <26 Years of Age
NCT05873751Not specifiedCOMPLETEDA Study to Learn About How Trumenba Vaccine Shots Work Against Gonorrhea Infection in Teenagers and Young Adults in the United States.

Clinical evidence (CIViC)

No CIViC predictive evidence (expected for non-precision-medicine drugs).

Pharmacology

Pharmacogenomics

No PharmGKB pharmacogenomic data curated for this drug.

No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).