Novaferon
drugOn this page
Also known as Nova (artificial interferon)
Summary
Novaferon (CHEMBL4650410) is a phase-3 clinical-stage unknown; indicated across 4 conditions including severe acute respiratory syndrome and neuroendocrine neoplasm.
At a glance
- Status: Max clinical phase 3 (not approved)
- Modality: Unknown
- Indications: 4 conditions
- Clinical trials: 6
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL4650410 |
| Name | Novaferon |
| Type | Unknown |
| Max phase | 3 |
Also known as: Nova (artificial interferon), Novaferon, NOVAFERON
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
4 indications (0 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).
| Indication | Trial phase | MONDO | EFO |
|---|---|---|---|
| severe acute respiratory syndrome | 3 | MONDO:0005091 | MONDO:0100096 |
| neuroendocrine neoplasm | 2 | MONDO:0019496 | EFO:1001901 |
| breast carcinoma | 1 | MONDO:0004989 | EFO:0000305 |
| hepatocellular carcinoma | 1 | MONDO:0007256 | EFO:0000182 |
Clinical trials
Total trials: 6.
Phase distribution
| Phase | Trials |
|---|---|
| PHASE3 | 3 |
| PHASE1/PHASE2 | 2 |
| PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT04669015 | PHASE3 | UNKNOWN | Phase 3 Inhaled Novaferon Study in Hospitalized Patients With Moderate to Severe COVID-19 |
| NCT04708158 | PHASE3 | UNKNOWN | Novaferon for COVID-19 Treatment Trial (NCTT-005) |
| NCT05172037 | PHASE3 | UNKNOWN | Novaferon in Non-hospitalized Adult Patients With Mild COVID-19 |
| NCT04380545 | PHASE1/PHASE2 | RECRUITING | Nivolumab, Fluorouracil, and Interferon Alpha 2B for the Treatment of Unresectable Fibrolamellar Cancer |
| NCT02068131 | PHASE2 | UNKNOWN | Recombinant Anti-tumor and Anti-virus Protein for Injection Plus Xeloda in Treatment of Metastatic Colorectal Cancer |
| NCT04418219 | PHASE1/PHASE2 | WITHDRAWN | Breast Cancer Vaccine in Combination With Pembrolizumab for Treatment of Persistent, Recurrent, or Metastatic Breast Cancer |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
- Diseases: severe acute respiratory syndrome