Olive Oil
drugOn this page
Also known as Olea europaea fruit oilOlea europaea oilOlivae oleum (ep)Olive leaf dry extractOlive oil component of smoflipid
Summary
Olive Oil (CHEMBL2107910) is an approved unknown; indicated across 14 conditions including hypertriglyceridemia and obesity disorder.
At a glance
- Status: Approved (max clinical phase 4)
- Modality: Unknown
- Indications: 14 conditions
- Clinical trials: 92
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL2107910 |
| Name | Olive Oil |
| Type | Unknown |
| Max phase | 4 |
Also known as: Olea europaea fruit oil, Olea europaea oil, Olivae oleum (ep), Olive leaf dry extract, Olive oil, Olive oil component of smoflipid, OLIVE OIL
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
14 indications (0 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).
| Indication | Trial phase | MONDO | EFO |
|---|---|---|---|
| hypertriglyceridemia | 3 | MONDO:0005347 | EFO:0004211 |
| obesity disorder | 2 | MONDO:0011122 | EFO:0001073 |
| osteoarthritis, knee | 2 | MONDO:0005416 | EFO:0004616 |
| psoriasis | 2 | MONDO:0005083 | EFO:0000676 |
| periodontal disorder | 2 | MONDO:0002635 | MONDO:0002635 |
| dry eye syndrome | 2 | MONDO:0006733 | EFO:1000906 |
| systemic lupus erythematosus | 2 | MONDO:0007915 | MONDO:0007915 |
| heart disorder | 1 | MONDO:0005267 | EFO:0003777 |
| dermatitis | 1 | MONDO:0002406 | MONDO:0002406 |
| periodontitis | 1 | MONDO:0005076 | EFO:0000649 |
| type 2 diabetes mellitus | 0 | MONDO:0005148 | MONDO:0005148 |
3 further indication records had no mapped disease name (EFO/MeSH-only) or were duplicates, and are omitted.
Clinical trials
Total trials: 92.
Phase distribution
| Phase | Trials |
|---|---|
| Not specified | 62 |
| PHASE4 | 9 |
| PHASE2 | 6 |
| PHASE1 | 6 |
| PHASE2/PHASE3 | 3 |
| PHASE3 | 3 |
| PHASE1/PHASE2 | 2 |
| EARLY_PHASE1 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT00507390 | PHASE4 | WITHDRAWN | Omega 3 Polyunsaturated Fatty Acid Supplements (PUFAs) and Microvolt T Wave Alternans (TWA) in Patients With Ventricular Arrhythmia |
| NCT00620529 | PHASE4 | COMPLETED | The Effects of Fish Oils on Blood Pressure, Heart Rate Variability and Liver Fat in the Polycystic Ovary Syndrome |
| NCT01067898 | PHASE4 | COMPLETED | A Study on Oral Vitamin D Megadoses |
| NCT01596842 | PHASE4 | COMPLETED | Effect of Omega-3 Fatty Acid on Vitamin D Activation |
| NCT01850979 | PHASE4 | COMPLETED | Treatment of Dry Eye Using 0.03% Tacrolimus Eye Drops |
| NCT02210962 | PHASE4 | UNKNOWN | Omega-3 Fatty Acids Efficacy in First-episode of Schizophrenia |
| NCT02214563 | PHASE4 | COMPLETED | Cholecalciferol Supplementation for Anemia and Mineral and Bone Disorder in Hemodialysis Patients |
| NCT03781557 | PHASE4 | UNKNOWN | Effects of Omega-3 Fatty Acids Supplement in Cognition of Young Healthy Adults and in Their Reaction Time of Computerized Test After 3 Months of Taking High-concentrated DHA and EPA Fish Softgels |
| NCT06254118 | PHASE4 | COMPLETED | Treatment of Periodontitis in Menopausal Patients |
| NCT06570889 | PHASE3 | RECRUITING | VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma |
| NCT00999687 | PHASE2/PHASE3 | COMPLETED | Evaluation of the Efficacy and Safety of Indigo Naturalis Oil Extract on Psoriatic Nails |
| NCT01102257 | PHASE2/PHASE3 | COMPLETED | Dry Eye Assessment and Management: Feasibility Study |
| NCT01193543 | PHASE2/PHASE3 | COMPLETED | Effect of Calanus Oli on Intra-abdominal Fat, Glucose Tolerance and Lipids in Man |
| NCT02009865 | PHASE3 | COMPLETED | Epanova® for Lowering Very High Triglycerides II (EVOLVE II) |
| NCT02166424 | PHASE3 | COMPLETED | The Synchronized Trial on Expectant Mothers With Depressive Symptoms by Omega-3 PUFAs (SYNCHRO) |
| NCT04417595 | PHASE2 | ACTIVE_NOT_RECRUITING | Omega-3 Fatty Acids for Smoking Cessation in Pregnancy |
| NCT06880926 | PHASE2 | NOT_YET_RECRUITING | Antarctic Krill Oil for Knee Osteoarthritis Pain |
| NCT00421161 | PHASE1/PHASE2 | UNKNOWN | Olive Oil With Omega 3 to Treat Stasis Dermatitis |
| NCT00670475 | PHASE2 | COMPLETED | Comparative Study of Olive Oil With Piroxicam Gel in Osteoarthritis of the Knee |
| NCT01347515 | PHASE1/PHASE2 | UNKNOWN | Bioactivity of Olive Oils Enriched With Their Own Phenolic Compounds (VOHF1) |
| NCT01772433 | PHASE2 | UNKNOWN | Olive Oil Phonophoresis and Chronic Low Back |
| NCT02021513 | PHASE2 | COMPLETED | Pilot Study - Effect of Omega-3 on Systemic Lupus Erythematosus |
| NCT03926351 | PHASE2 | UNKNOWN | High Dose Omega 3 in People at Risk for Dementia |
| NCT00798226 | PHASE1 | ACTIVE_NOT_RECRUITING | Fish Oil Supplementation During Pregnancy for Prevention of Asthma, Eczema and Allergies in Childhood |
| NCT00988585 | PHASE1 | COMPLETED | Evaluation of the Safety and Biologic Effects of an Eicosapentaenoic (EPA)-Enriched Oil |
| NCT03395119 | PHASE1 | COMPLETED | Efficacy of Fish Oil or Olive Oil Supplementation on the Health Effects of Ozone Exposure in Healthy Young Subjects |
| NCT03399331 | PHASE1 | COMPLETED | Honey or Olive Oil for Treating Oral Mucositis in Children and Adults With Leukemia Receiving Intensive Chemotherapy |
| NCT03544411 | PHASE1 | COMPLETED | Effects of Olive Oil and Bran Oil on Antioxidant Levels, Glycemic Control, and Lipid Profile in Patient Type 2 DM |
| NCT03614520 | PHASE1 | COMPLETED | Evaluation of Bioavailability and Metabolism of Diet Phenolic Compounds |
| NCT01453842 | EARLY_PHASE1 | COMPLETED | Diet Oil Induced Stimulation of GLP-1 |
| NCT05465252 | Not specified | RECRUITING | Effect of Omega-3 Fatty Acid Supplementation on Dry-AMD Progression |
| NCT06880939 | Not specified | NOT_YET_RECRUITING | Antarctic Krill Oil Functional Food Mitigates Bladder Cancer Treatment Side Effects |
| NCT00728338 | Not specified | COMPLETED | Docosahexenoic Acid (DHA) Supplementation and Cardiovascular Disease in Men With High Triglycerides |
| NCT00876356 | Not specified | COMPLETED | The Health Benefits of Conjugated Linoleic Acid (CLA) for Asthma & Allergy |
| NCT00885053 | Not specified | COMPLETED | Fish Oil and Inflammation in Overweight Subjects |
| NCT00941837 | Not specified | COMPLETED | Effect of Dietary Fat Type in Combination With High Protein on Plasma Homocysteine Levels |
| NCT01083771 | Not specified | COMPLETED | Med Diet Prevention Metabolic Syndrome Men Undergoing Androgen Deprivation Therapy Prostate Cancer |
| NCT01258335 | Not specified | COMPLETED | Omega-3-fatty Acids on Age-related Macular |
| NCT01315327 | Not specified | COMPLETED | Omega-3 Fatty Acids in Tourette’s Disorder |
| NCT01353807 | Not specified | COMPLETED | Impact of Fish Oil Supplementation in 3rd Trimester of Pregnancy on Maternal and Offspring Health |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
- Diseases: hypertriglyceridemia