Oxolamine

drug
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Also known as AF-438 FREE BASEOksalaminOxolaminaSKF 9976 FREE BASESKF-9976 FREE BASEOXOLAMINE CITRATE

Summary

Oxolamine (CHEMBL1620875) is a phase-3 clinical-stage small molecule (ATC R05DB07); indicated across 1 condition.

At a glance

  • Status: Max clinical phase 3 (not approved)
  • Modality: Small molecule
  • ATC class: R05DB07
  • Indications: 1 condition
  • Chemistry: 245.32 Da · C14H19N3O

Identifiers

Drug identity and classification

FieldValue
ChEMBL IDCHEMBL1620875
NameOxolamine
TypeSmall molecule
Max phase3
FDA approvedno
PubChem CID13738
ATCR05DB07
Molecular formulaC14H19N3O
Molecular weight245.32
InChIKeyIDCHQQSVJAAUQQ-UHFFFAOYSA-N

SMILES: CCN(CC)CCC1=NC(=NO1)C2=CC=CC=C2

IUPAC name: N,N-diethyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine

Also known as: AF-438 FREE BASE, Oksalamin, Oxolamina, Oxolamine, SKF 9976 FREE BASE, SKF-9976 FREE BASE, OXOLAMINE, OXOLAMINE CITRATE, oxolamine

Parent form; salt/anhydrous children: CHEMBL1448044

Patent coverage: 164 distinct patent families (477 SureChEMBL compound mentions), from 1 matched compound structure(s). Mentions count patents naming the compound (not distinct inventions), so promiscuous / reference molecules inflate the mention figure — families are the dedup metric.

Targets

Targets

Broader ChEMBL bioactivity targets: 2 (assay-derived). Sample: 5-hydroxytryptamine receptor 1A, Histamine H3 receptor.

Bioactivity

No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).

Target pathways

No target-pathway data for this drug (no mapped target genes).

Indications & clinical

Indications

1 indication record carries no mapped disease name (EFO/MeSH-only); none shown.

Clinical trials

Total trials: 0.

Clinical evidence (CIViC)

No CIViC predictive evidence (expected for non-precision-medicine drugs).

Pharmacology

Pharmacogenomics

No PharmGKB pharmacogenomic data curated for this drug.

No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).

No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.