Paramethadione

Summary

Paramethadione (CHEMBL1100) is an approved small-molecule anticonvulsant (ATC N03AC01); indicated across 1 condition including epilepsy.

At a glance

• Status: Approved (max clinical phase 4)
• Modality: Small molecule
• ATC class: N03AC01
• Indications: 1 condition
• Chemistry: 157.17 Da · C7H11NO3

Identifiers

Drug identity and classification

Field	Value
ChEMBL ID	CHEMBL1100
Name	Paramethadione
Type	Small molecule
Max phase	4
FDA approved	no
PubChem CID	8280
ChEBI	CHEBI:7921
ATC	N03AC01
Molecular formula	C7H11NO3
Molecular weight	157.17
InChIKey	VQASKUSHBVDKGU-UHFFFAOYSA-N

SMILES: CCC1(C(=O)N(C(=O)O1)C)C

IUPAC name: 5-ethyl-3,5-dimethyl-1,3-oxazolidine-2,4-dione

Pharmacological roles (ChEBI): anticonvulsant.

Also known as: NSC-760129, Paradione, Parametadiona, Paramethadione, PARAMETHADIONE

Patent coverage: 927 distinct patent families (3,953 SureChEMBL compound mentions), from 1 matched compound structure(s). Mentions count patents naming the compound (not distinct inventions), so promiscuous / reference molecules inflate the mention figure — families are the dedup metric.

Targets

Targets

No target linkage available.

Bioactivity

No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).

Target pathways

No target-pathway data for this drug (no mapped target genes).

Indications & clinical

Indications

1 indication (1 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).

Indication	Trial phase	MONDO	EFO
epilepsy	4	MONDO:0005027	EFO:0000474

Clinical trials

Total trials: 0.

Clinical evidence (CIViC)

No CIViC predictive evidence (expected for non-precision-medicine drugs).

Pharmacology

Pharmacogenomics

No CPIC/DPWG dosing guideline or drug-level clinical/variant annotations in PharmGKB for this molecule.

Related molecules

Related molecules

No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).