POLYGLACTIN 910
drugOn this page
Also known as VicrylXLG
Summary
Polyglactin 910 (CHEMBL2108539) is a phase-3 clinical-stage small molecule.
At a glance
- Status: Max clinical phase 3 (not approved)
- Modality: Small molecule
- Clinical trials: 26
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL2108539 |
| Name | POLYGLACTIN 910 |
| Type | Small molecule |
| Max phase | 3 |
Also known as: Polyglactin 910, Vicryl, XLG, POLYGLACTIN 910
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
0 indications (0 at ChEMBL trial phase 4).
Clinical trials
Total trials: 26.
Phase distribution
| Phase | Trials |
|---|---|
| Not specified | 16 |
| PHASE4 | 8 |
| PHASE3 | 1 |
| PHASE1 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT01019447 | PHASE4 | COMPLETED | The Impact of Using Triclosan-antibacterial Sutures on the Incidence of Surgical Site Infection |
| NCT02533492 | PHASE4 | COMPLETED | Compare Antimicrobial to Conventional Suture in Patients Receiving Primary Total Knee Replacement |
| NCT02847936 | PHASE4 | UNKNOWN | Efficacy of Triclosan-coated Sutures in the Episiotomy |
| NCT03305757 | PHASE4 | COMPLETED | Seroma Reduction After Mastectomy |
| NCT03386240 | PHASE4 | COMPLETED | Antibacterial-coated Sutures at Time of Cesarean |
| NCT04255927 | PHASE4 | COMPLETED | Triclosan-antibacterial Sutures Impact on the Incidence of Surgical Site Infection in Laparoscopic Surgeries. |
| NCT04256824 | PHASE4 | UNKNOWN | Triclosan-antibacterial Sutures Efficacy on the Incidence of Surgical Site Infection in Clean-contaminated Wounds |
| NCT05330650 | PHASE4 | COMPLETED | Evaluation of Triclosan Coated Suture in Obstetrical Surgery |
| NCT02962011 | PHASE3 | COMPLETED | Trial Comparing Barbed and Non-barbed Suture for Uterine Incision Closure at Cesarean Section |
| NCT00576745 | PHASE1 | COMPLETED | A Comparison Of The 3M TM S Surgical Skin Closure System To The Standard Vicryl Suture Closure of Sternotomy Incisions During Cardiac Surgery |
| NCT06543329 | Not specified | NOT_YET_RECRUITING | Comparative Analysis of Subcuticular Suture Materials in Cesarean Section |
| NCT00932503 | Not specified | COMPLETED | Antiseptic Sutures and Wound Infection |
| NCT00946049 | Not specified | COMPLETED | Oral Bacteria on Suture Materials - Clinical Comparison of an Antibacterial-coated and a Non-coated Suture Material |
| NCT01313754 | Not specified | COMPLETED | Comparison of Skin Incision Closure Material for the Transobturator Suburethral Sling Procedure |
| NCT02519829 | Not specified | COMPLETED | A Clinical Trial Comparing Monocryl and Dermabond Closure Versus Staple Closure in Total Hip Arthroplasty |
| NCT02653924 | Not specified | UNKNOWN | The Comparison of Microbial Adherence to Various Sutures in Patients Undergoing Oral Surgery |
| NCT02696239 | Not specified | COMPLETED | Vaginal Cuff Closure in Robotic Hysterectomy |
| NCT02720718 | Not specified | COMPLETED | Comparison of Laparoscopic Traditional and Knotless Sutures |
| NCT03159871 | Not specified | COMPLETED | Closing Uterine Incision During C-section Using Barbed Suture (Stratafix) or Vicryl Suture. |
| NCT03285529 | Not specified | COMPLETED | The Use of STRATAFIX Suture Device Compared to Standard-of-care for Deep Tissue Closure in Total Knee Arthroplasty |
| NCT03285555 | Not specified | COMPLETED | Prospective Randomized Trial of Stratafix vs. Vicryl in Total Hip Arthroplasty. |
| NCT03659344 | Not specified | COMPLETED | Efficacy of Antimicrobial Coating Suture Coated Vicryl Plus Compared With Vicryl in Reduced Surgical Site Infection of Dental Implant Surgeries: A Uni-Blind Randomized Clinical Trial Study |
| NCT03792737 | Not specified | COMPLETED | A Study of Two Types of Absorbable Surgical Sutures in the Suturing of Thyroid Surgery Incision |
| NCT03812640 | Not specified | UNKNOWN | Nylon Verus Polyglactin Corneal Suture in Pediatric Cataract Surgery |
| NCT04613635 | Not specified | COMPLETED | Stratafix vs. Vicryl OAGB / MGB Suture Study |
| NCT05770115 | Not specified | COMPLETED | A Randomized Clinical Study Based on Comparison Between Closure of Uterine Incision With Vicryl 2/0 Versus Vicryl 1 in Development of Uterine Niche. |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.