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Atlas / Drug / Propolis Wax

Propolis Wax

drug
On this page

Also known as Bee propolisFengjiaoPropolisPropolis cera

Summary

Propolis Wax (CHEMBL4298075) is a phase-3 clinical-stage small molecule; indicated across 10 conditions including chronic kidney disease and dental pulp disorder.

At a glance

  • Status: Max clinical phase 3 (not approved)
  • Modality: Small molecule
  • Indications: 10 conditions
  • Clinical trials: 45

Identifiers

Drug identity and classification

FieldValue
ChEMBL IDCHEMBL4298075
NamePropolis Wax
TypeSmall molecule
Max phase3

Also known as: Bee propolis, Fengjiao, Propolis, Propolis cera, Propolis wax, PROPOLIS WAX

Targets

Targets

No target linkage available.

Bioactivity

No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).

Target pathways

No target-pathway data for this drug (no mapped target genes).

Indications & clinical

Indications

7 diseases in clinical trials (phase 1–3, investigational — not approved indications). Highest ChEMBL trial phase per disease; a non-cancer approved use is occasionally logged at phase 3 here.

Disease (in trials)PhaseMONDOEFO
chronic kidney disease2MONDO:0005300EFO:0003884
dental pulp disorder2MONDO:0003394EFO:0009540
severe acute respiratory syndrome2MONDO:0005091MONDO:0100096
type 2 diabetes mellitus2MONDO:0005148MONDO:0005148
allergic disease2MONDO:0005271MONDO:0005271
dental caries2MONDO:0005276EFO:0003819
periodontal disorder2MONDO:0002635MONDO:0002635

2 further indication records had no mapped disease name (EFO/MeSH-only) or were duplicates, and are omitted.

Clinical trials

Total trials: 45.

Phase distribution

PhaseTrials
Not specified25
PHASE27
PHASE34
PHASE43
EARLY_PHASE13
PHASE2/PHASE32
PHASE1/PHASE21

Top trials by phase / activity

NCTPhaseStatusTitle
NCT06903546PHASE4RECRUITINGThe Effect of Propolis Administration on Cholesterol Level in Diabetic Type 2 Patients
NCT02794506PHASE4COMPLETEDPropolis Improves Glycemic Control in Subjects With Type 2 Diabetes and Chronic Periodontitis
NCT03533231PHASE4COMPLETEDEfficiency of Triple Antibiotic Paste, Ciprofloxacin/Propolis, Ciprofloxacin/Metronidazole, Propolis/Metronidazole Combinations on Revascularization Process of Immature Necrotic Maxillary Incisors of Patients 8-18 Years Old.
NCT01750801PHASE3UNKNOWNEfficacy of a Mouthwash Containing Propolis
NCT02818803PHASE3COMPLETEDEfficacy of Standardized-propolis Extract (EPP-AF®) Gel Formulation as Buccal Antiseptic
NCT03723980PHASE3COMPLETEDRole of Propolis Paste in Preventing Pain After Root Canal Treatment.
NCT04819867PHASE2/PHASE3COMPLETEDComparison Of The Effect Of Propolis And Gluma Desensitizer On The Management Of Dentin Hypersensitivity
NCT05974748PHASE3COMPLETEDRole of Propolis Endodontic Irrigant on Post-Operative Pain
NCT06455007PHASE2/PHASE3COMPLETEDPropolis as a Treatment Option for Hand Foot and Mouth Disease
NCT07073092PHASE2NOT_YET_RECRUITINGPropolis for Management of Chemotherapy-Induced Oral Mucositis in Pediatric Patients
NCT01375088PHASE2COMPLETEDAssessing the Preventing and Therapeutic Effect of Propolis in Radiotherapy Induced Mucositis of Head and Neck Cancers
NCT02052973PHASE1/PHASE2COMPLETEDEfficacy of Propolis Varnish Against Oral Biofilm
NCT02766036PHASE2COMPLETEDPropolis Effects in Patients With Chronic Kidney Disease
NCT03416127PHASE2COMPLETEDEffect of Propolis or Metformin Administration on Glycemic Control in Patients With Type 2 Diabetes Mellitus
NCT03580135PHASE2UNKNOWNPostoperative Pain Evaluation of Mineral Trioxide Aggregate and Propolis After Pulpotomy in Carious Primary Molars
NCT03812315PHASE2COMPLETEDAntimicrobial Effect OF Propolis Administrated Through Two Different Vehicles In High Caries Risk Children
NCT05870059PHASE2COMPLETEDComparative Evaluation of Propolis Mouthwash With 0.2% Chlorhexidine Mouthwash in Improving the Periodontitis
NCT04374006EARLY_PHASE1COMPLETEDEffects of Sulawesi Propolis Extract on Lesion Growth, Apoptotic and Inflammatory Activity of the Rat Endometriosis Tissue
NCT04754763EARLY_PHASE1COMPLETEDA Comparative Study On The Effect Of Propolis And Dentine Bonding Agent In Treating Dentine Hypersensitivity
NCT05413096EARLY_PHASE1COMPLETEDCombination of Diclofenac Potassium and Propolis in the Therapy of Oral Aphthosis
NCT05183737Not specifiedACTIVE_NOT_RECRUITINGEffects of Microencapsulated Propolis and Turmeric in Patients With Chronic Kidney Disease
NCT07578311Not specifiedNOT_YET_RECRUITINGEffect of a Herbal Intracanal Medication On Postoperative Pain And Flare up Incidence In Non Surgical Root Canal Retreatment
NCT07596992Not specifiedNOT_YET_RECRUITINGEffects of Royal Jelly and Propolis on Metabolomic Signatures, Inflammation, and Cardiovascular Risk in Patients With Coronary Artery Disease.
NCT01943877Not specifiedUNKNOWNPropolis In The Treatment Of Periodontitis
NCT03591172Not specifiedUNKNOWNUsing Three Different Final Irrigants and Showing Their Effects on the Success of Revascularization
NCT03623048Not specifiedUNKNOWNEffect of Natural Antibacterial Mouthwash on Taste, Salivary pH and Bacteria in High Caries Risk pt
NCT03649243Not specifiedCOMPLETEDPropolis as Adjuvant in the Healing of Human Diabetic Foot Wounds
NCT04032548Not specifiedCOMPLETEDEffectiveness of Propolis Mouthwash on Gingivitis
NCT04117451Not specifiedCOMPLETEDThe Effect of Propolis Mouthwash Compared to Chlorhexidine Mouthwash on Oral and Cardiovascular Health
NCT04145102Not specifiedCOMPLETEDEvaluation of the Remineralizing and Antibacterial Effect of Natural Versus Synthetic Materials on Deep Carious Dentin
NCT04382079Not specifiedCOMPLETEDHoney Products for Cancer Patients With Oral Mucositis: a Randomized Controlled Trial
NCT04411758Not specifiedCOMPLETEDPropolis for Patients With Chronic Kidney Disease.
NCT04680819Not specifiedUNKNOWNEvaluation of the Effect of Anatolian Propolis on Covid-19 in Healthcare Professionals
NCT04843644Not specifiedUNKNOWNMicrobiota and Symptom Distress in Head and Neck Cancer Patients Receiving Radiotherapy
NCT04916821Not specifiedUNKNOWNInvestigation of Clinical Effectiveness of Propolis Extracts as Food Supplements in Patients With SARS-CoV-2(COVID-19)
NCT04983524Not specifiedCOMPLETEDPropolis Versus Calcium Hydroxide on Post-Operative Pain in Patients With Necrotic Pulp
NCT05083052Not specifiedCOMPLETEDPropolis in Reducing Dentin Hypersensitivity
NCT05400031Not specifiedCOMPLETEDOral Care With Propolis in Pediatric Oncology Patients
NCT05569590Not specifiedCOMPLETEDEfficacy of Desensitizing Agent,Propolis After an In-office Vital Tooth Bleaching.
NCT05625841Not specifiedUNKNOWNEffects for Oral Mucositis Care During Chemoradiotherapy in Cancer Patients: Evaluation of the Bee Products
NCT05717881Not specifiedCOMPLETEDImpact of Poplar Propolis on Metabolic Disturbances of Insulin Resistance
NCT05770297Not specifiedUNKNOWNEffect of Propolis Administration for Dysmenorrhea in Endometriosis Patient With Levonorgestrel Implant Therapy
NCT06216262Not specifiedCOMPLETEDEvaluation of the Effectiveness of Home-Use Desensitizing Agents on Dentin Hypersensitivity
NCT06936228Not specifiedCOMPLETEDEvaluation of the Effect of Local Propolis Application on the Healing of Pressure Ulcers
NCT07197073Not specifiedCOMPLETEDAntibacterial Effect of Ozonated Olive Oil, Propolis and Chlorhexidine Mouthwashes in Pediatric Patients

Clinical evidence (CIViC)

No CIViC predictive evidence (expected for non-precision-medicine drugs).

Pharmacology

Pharmacogenomics

No PharmGKB pharmacogenomic data curated for this drug.

No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).

About this page

Generated deterministically by Sugi Atlas from primary biomedical databases via BioBTree. Every record on this page traces to a primary source.

Generated
Atlas version
v1.1.4
BioBTree
v2.0.2

Sources 14

This page pulls from 14 datasets indexed by BioBTree:

chebichembl_activitychembl_moleculechembl_targetcivic_evidenceclinical_trialsefogtopdb_ligandmeshmondopatent_compoundpharmgkbpharmgkb_guidelinepubchem