Segesterone Acetate

Summary

Segesterone Acetate (CHEMBL3707377) is an approved small molecule.

At a glance

• Status: Approved (max clinical phase 4)
• Modality: Small molecule
• Clinical trials: 3
• Chemistry: 370.5 Da · C23H30O4

Identifiers

Drug identity and classification

Field	Value
ChEMBL ID	CHEMBL3707377
Name	Segesterone Acetate
Type	Small molecule
Max phase	4
FDA approved	no
PubChem CID	108059
Molecular formula	C23H30O4
Molecular weight	370.5
InChIKey	CKFBRGLGTWAVLG-GOMYTPFNSA-N

SMILES: CC(=O)[C@]1(C(=C)C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@H]34)C)OC(=O)C

IUPAC name: [(8R,9S,10R,13S,14S,17R)-17-acetyl-13-methyl-16-methylidene-3-oxo-2,6,7,8,9,10,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate

Also known as: Elcometrine, Nestorone, Segesterone acetate, ST-1435, SEGESTERONE ACETATE

Patent coverage: 161 distinct patent families (439 SureChEMBL compound mentions), from 1 matched compound structure(s). Mentions count patents naming the compound (not distinct inventions), so promiscuous / reference molecules inflate the mention figure — families are the dedup metric.

Targets

Targets

No target linkage available.

Bioactivity

No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).

Target pathways

No target-pathway data for this drug (no mapped target genes).

Indications & clinical

Indications

0 indication records carry no mapped disease name (EFO/MeSH-only); none shown.

Clinical trials

Total trials: 3.

Phase distribution

Phase	Trials
PHASE2	2
PHASE1	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT00213096	PHASE2	COMPLETED	Effects of Hormonal Contraceptives on Liver Proteins and Coagulation Factors: A Comparison of a Contraceptive Vaginal Ring and an Oral Contraceptive
NCT03452111	PHASE2	COMPLETED	Study of Daily Application of Nestorone® (NES) and Testosterone (T) Combination Gel for Male Contraception
NCT02994602	PHASE1	COMPLETED	Study of Serum Testosterone and Nestorone in Females After Secondary Exposure to Nestorone ® (NES) + Testosterone (T) Combined Gel Applied to Shoulders and Upper Arms in Males

Clinical evidence (CIViC)

No CIViC predictive evidence (expected for non-precision-medicine drugs).

Pharmacology

Pharmacogenomics

No PharmGKB pharmacogenomic data curated for this drug.

Related molecules

Related molecules

No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).