Starch
drugOn this page
Also known as Bio-sorb
Summary
Starch (CHEMBL2108866) is a phase-3 clinical-stage unknown; indicated across 16 conditions including irritable bowel syndrome and diarrheal disease.
At a glance
- Status: Max clinical phase 3 (not approved)
- Modality: Unknown
- Indications: 16 conditions
- Clinical trials: 61
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL2108866 |
| Name | Starch |
| Type | Unknown |
| Max phase | 3 |
Also known as: Bio-sorb, Starch, STARCH
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
16 indications (0 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).
| Indication | Trial phase | MONDO | EFO |
|---|---|---|---|
| irritable bowel syndrome | 3 | MONDO:0005052 | EFO:0000555 |
| diarrheal disease | 3 | MONDO:0001673 | HP:0002014 |
| obesity disorder | 2 | MONDO:0011122 | EFO:0001073 |
| subarachnoid hemorrhage | 2 | MONDO:0005099 | EFO:0000713 |
| hypertensive disorder | 2 | MONDO:0005044 | EFO:0000537 |
| temporomandibular joint disorder | 2 | MONDO:0005473 | EFO:0005279 |
| blood coagulation disease | 2 | MONDO:0001531 | EFO:0009314 |
| severe acute respiratory syndrome | 2 | MONDO:0005091 | MONDO:0100096 |
| psoriasis | 1 | MONDO:0005083 | EFO:0000676 |
| bone fracture | 1 | MONDO:0005315 | EFO:0003931 |
| intracerebral hemorrhage | 1 | MONDO:0013792 | EFO:0005669 |
| infertility disorder | 0 | MONDO:0005047 | EFO:0000545 |
| neoplasm | 0 | MONDO:0005070 | EFO:0000616 |
| pulmonary edema | 0 | MONDO:0006932 | EFO:1001134 |
2 further indication records had no mapped disease name (EFO/MeSH-only) or were duplicates, and are omitted.
Clinical trials
Total trials: 61.
Phase distribution
| Phase | Trials |
|---|---|
| Not specified | 41 |
| PHASE4 | 7 |
| PHASE3 | 4 |
| PHASE2 | 4 |
| PHASE2/PHASE3 | 2 |
| PHASE1/PHASE2 | 1 |
| EARLY_PHASE1 | 1 |
| PHASE1 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT01269827 | PHASE4 | COMPLETED | Pentoxifylline and Systemic Inflammation in Hemodialysis Patients |
| NCT01303601 | PHASE4 | COMPLETED | Efficacy of Olanzapine Monotherapy for Treatment Bipolar Ⅰ Depression |
| NCT01956682 | PHASE4 | COMPLETED | Hypoallergenic Infant Formula Containing Starch and the Probiotic: Effect on Gastric Emptying |
| NCT02644577 | PHASE4 | COMPLETED | Metformin for Treatment Antipsychotic-induced Metabolic Syndrome in Bipolar Disorder Patients |
| NCT03684707 | PHASE4 | UNKNOWN | Cancer Chemoprevention by Metformin Hydrochloride Compared to Placebo in Oral Potentially Malignant Lesions |
| NCT03917784 | PHASE4 | UNKNOWN | Effect of Oral Supplementation With Curcumin on Insulin Sensitivity in Subjects With Prediabetes |
| NCT04432675 | PHASE4 | COMPLETED | Effects of Crystal Solution and Colloid Solution on Mother and Fetus |
| NCT07504198 | PHASE2/PHASE3 | NOT_YET_RECRUITING | Neuroprotection of Memantine and Rosuvastatin |
| NCT01088971 | PHASE3 | COMPLETED | Effect of Duolac 7S Administration on Improving Symptom in Irritable Bowel Syndrome |
| NCT02502773 | PHASE3 | COMPLETED | Fluid Loading in Abdominal Surgery: Saline Versus Hydroxyethyl Starch (FLASH Study) |
| NCT02504060 | PHASE3 | UNKNOWN | Clinical Trials of N-acetyl Glucosamine Capsule for IBS-D Treatment |
| NCT02698046 | PHASE3 | UNKNOWN | Oral Iron Therapy in Chronic Heart Failure Patients |
| NCT04342689 | PHASE2/PHASE3 | TERMINATED | The Role of Resistant Starch in COVID-19 Infection |
| NCT06091332 | PHASE2 | RECRUITING | Hemorrhagic Brainstem Cavernous Malformations Treatment With Sirolimus: aSingle Centre, Randomized, Placebo-controlled Pilot Trial |
| NCT00823953 | PHASE2 | WITHDRAWN | Glycemic Response to Momordica Charantia in Type 2 Diabetes |
| NCT02763033 | PHASE2 | COMPLETED | Dietary Manipulation of the Microbiome-metabolomic Axis for Mitigating GVHD in Allo HCT Patients |
| NCT03048903 | PHASE2 | UNKNOWN | The Effect of Rhubarb on Sepsis and Post-traumatic Gastrointestinal Function Failure |
| NCT03805347 | PHASE1/PHASE2 | COMPLETED | The Therapeutic Effect of Dau-Di-Wu-Gong in Patient With Ankle Fracture |
| NCT05630534 | PHASE1 | UNKNOWN | Minocycline Accelerates Intracerebral Hemorrhage Absorption |
| NCT01233024 | EARLY_PHASE1 | COMPLETED | Satiety Response of Four Dietary Fibers |
| NCT04520594 | Not specified | ACTIVE_NOT_RECRUITING | OptiMized REsistaNt Starch in Inflammatory Bowel Disease: The MEND Trial |
| NCT04522271 | Not specified | ACTIVE_NOT_RECRUITING | Resistant Starch in Pediatric Inflammatory Bowel Disease (Crohn’s Disease or Ulcerative Colitis) |
| NCT05135351 | Not specified | RECRUITING | Study Using Prebiotics to Improve Gut Microbiome Diversity After Autologous Cellular Therapy |
| NCT06083350 | Not specified | ACTIVE_NOT_RECRUITING | Effects of Yeast Beta-glucan on Cognitive Function in Patients With Mild Cognitive Impairment |
| NCT06301477 | Not specified | ACTIVE_NOT_RECRUITING | PRecisiOn Microbiome Directed ExtensiOn of Anti-TNFα Crohn’s Disease ThErapy in Children: The PROMOTE Trial |
| NCT06897241 | Not specified | RECRUITING | Personalized Metabolic Responses to Rapid, Slow and Resistant Starch |
| NCT07096635 | Not specified | NOT_YET_RECRUITING | Oral Melatonin With Intra Articular Analgesia on Pain After Arthroscopic Anterior Cruciate Ligament Reconstruction |
| NCT07486141 | Not specified | ACTIVE_NOT_RECRUITING | Effect of Vitamin D and Folic Acid on Mild Cognitive Impairment |
| NCT07564947 | Not specified | ENROLLING_BY_INVITATION | Impact of Ganoderma Lucidum on NRF2 Levels and Antioxidant Status in Metabolic Asscociated Fatty Liver Disease (GL-MAFLD-NRF2 Study) |
| NCT00518544 | Not specified | UNKNOWN | Hemostatic Effect of Various Colloid Solutions |
| NCT00930956 | Not specified | COMPLETED | Comparison of Different Types of Resistant Starch |
| NCT00958399 | Not specified | COMPLETED | Satiety, Glycemic, and Gastrointestinal Effects of Novel Fibers |
| NCT00976274 | Not specified | COMPLETED | Korean Red Ginseng and Metabolic Syndrome |
| NCT01142960 | Not specified | COMPLETED | Effects of Lycium Barbarum Supplements on the Progression of Senile Cataract in Hong Kong Chinese Population |
| NCT01423487 | Not specified | WITHDRAWN | Efficacy and Safety of Metformin in Preventing Patients With Risperidone From Weight Gain and Amenorrhea |
| NCT01580358 | Not specified | UNKNOWN | Therapeutic Effects of Traditional Chinese Medicine, Shen-Mai San in Cancer Patient Undergoing Chemotherapy or Radiotherapy |
| NCT01590485 | Not specified | COMPLETED | Evaluation of the Effect of Saffron (Crocus Sativus) on Pain Control After Root Canal Therapy in Teeth With Vital Pulps |
| NCT01910558 | Not specified | WITHDRAWN | The Effect of Oral Alpha-Cyclodextrin on Fecal Fat Excretion |
| NCT02129946 | Not specified | COMPLETED | The Effect of Resistant Starch Bagels on Risk Factors of Type 2 Diabetes and Colorectal Cancer |
| NCT02161250 | Not specified | COMPLETED | Effects of Resistant Starch in a Beverage on Post-prandial Glycemic and Insulinemic Responses |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
- Diseases: irritable bowel syndrome, diarrheal disease