Syrup

Summary

Syrup (CHEMBL2108693) is a phase-3 clinical-stage unknown; indicated across 8 conditions including perennial allergic rhinitis and bronchial disorder.

At a glance

• Status: Max clinical phase 3 (not approved)
• Modality: Unknown
• Indications: 8 conditions
• Clinical trials: 56

Identifiers

Drug identity and classification

Field	Value
ChEMBL ID	CHEMBL2108693
Name	Syrup
Type	Unknown
Max phase	3

Also known as: Simple syrup, Syrup, SYRUP

Targets

Targets

No target linkage available.

Bioactivity

No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).

Target pathways

No target-pathway data for this drug (no mapped target genes).

Indications & clinical

Indications

8 indications (0 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).

Indication	Trial phase	MONDO	EFO
perennial allergic rhinitis	3	MONDO:0024332	EFO:1001417
bronchial disorder	3	MONDO:0001358	EFO:1002018
otitis media	3	MONDO:0005441	MONDO:0024330
obesity disorder	2	MONDO:0011122	EFO:0001073
sensorineural hearing loss disorder	2	MONDO:0020678	EFO:1001176
allergic rhinitis	1	MONDO:0011786	EFO:0005854

2 further indication records had no mapped disease name (EFO/MeSH-only) or were duplicates, and are omitted.

Clinical trials

Total trials: 56.

Phase distribution

Phase	Trials
Not specified	29
PHASE1	9
PHASE4	8
PHASE3	5
PHASE2	4
EARLY_PHASE1	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT05444699	PHASE4	RECRUITING	Oral Prednisolone for Acute Rhinovirus Induced Wheezing in Children Less Than 2 Years of Age
NCT01154153	PHASE4	COMPLETED	Nasacort AQ Hypothalamic-Pituitary-Adrenal (HPA) Axis Study in Children With Allergic Rhinitis
NCT01533818	PHASE4	TERMINATED	Community Based Management of Fast Breathing in Infants Aged < 60 Days in Low-income Settlements of Karachi
NCT01830881	PHASE4	COMPLETED	Evaluation of Oral Midazolam in First-trimester Surgical Abortions
NCT01977937	PHASE4	COMPLETED	Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin
NCT02894723	PHASE4	UNKNOWN	L-arginine Treatment in Mild Hypertension
NCT03117192	PHASE4	COMPLETED	Zinc Supplementation on Cellular Immunity in Thalassemia Major
NCT05366231	PHASE4	COMPLETED	Kesuting Syrup in the Treatment of Corona Virus Disease 2019 (COVID-19)
NCT01044030	PHASE3	COMPLETED	Xylitol Syrup for the Prevention of Acute Otitis Media in Otitis-prone Children
NCT01119534	PHASE3	UNKNOWN	Comparative Efficacy of the Suppository Versus Guaiacol Suppository Versus Guaifenesin Syrup in Pediatric Patients With Cough Due the Infectious Origin
NCT02151734	PHASE3	COMPLETED	Safety and Efficacy of KALOMIN™ Tab. in Patients With Acute Bronchitis
NCT02581397	PHASE3	TERMINATED	Transpulmin Suppository and Guaiacol Compared to Transpulmin Syrup in Pediatric Participants With Productive Cough
NCT05563064	PHASE3	UNKNOWN	Effect of Herbal Formulation on Thrombocytes Count
NCT03107871	PHASE2	ACTIVE_NOT_RECRUITING	Randomized Controlled Trial of Valganciclovir for Cytomegalovirus Infected Hearing Impaired Infants
NCT00891917	PHASE2	WITHDRAWN	Liq-NOL Efficacy in Pediatric Patients With Down Syndrome
NCT01928849	PHASE2	COMPLETED	Valproic Acid for the Prevention of Post-Amputation Pain
NCT02045550	PHASE2	UNKNOWN	Tolerance and Effect of a Prophylactical Treatment With Ivy Leaves Dry Extract in Recurrent Wheezy Bronchitis
NCT02082665	PHASE1	COMPLETED	Effects of Dabrafenib on the Single Dose Pharmacokinetics (PK) of Rosuvastatin and Midazolam
NCT02182960	PHASE1	COMPLETED	Bioavailability of Ibuprofen Enantiomers Compared With Standard Brufen Sirup in Healthy Male Volunteers
NCT02191709	PHASE1	COMPLETED	Relative Bioavailability of Dextromethorphan Syrup in Comparison to Dextromethorphan Soft Pastilles in Healthy Male and Female Subjects
NCT02204501	PHASE1	COMPLETED	A Drug-Drug Interaction Study to Evaluate the Effect of Vapendavir on the Pharmacokinetics of Midazolam in Healthy Male and Female Volunteers
NCT02260063	PHASE1	COMPLETED	Relative Bioavailability of Epinastine Syrup Compared to Tablets in Healthy Volunteers
NCT02768519	PHASE1	COMPLETED	Study to Evaluate Systemic Bioavailability of Oral OTS167 in Healthy Adult Subjects
NCT02858193	PHASE1	COMPLETED	Crossover, Single Dose, Two-stage Bioequivalence Study of SCMC-Lys Salt 1.35 g Powder vs SCMC-Lys Salt 90 mg/mL Syrup
NCT05504876	PHASE1	COMPLETED	Pharmacokinetics of Midazolam When Co-administered With HEC74647 and HEC110114
NCT06180967	PHASE1	COMPLETED	A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LOXO-305) and Different Formulations of Midazolam in Healthy Participants
NCT05781685	EARLY_PHASE1	COMPLETED	The Influence of Testosterone on Experimental Pain Perception
NCT06268184	Not specified	RECRUITING	Effect of Omega 3 on Oxidative Stress and Nutritional Status of Children on Regular Dialysis
NCT06377410	Not specified	RECRUITING	Efficacy & Safety of Dry Powder Ivy Extract (Syrup Prospan) Versus NAC Among COPD Patients
NCT06816524	Not specified	NOT_YET_RECRUITING	The Effects of Iron Treatment on Malaria and Measles Vaccine Response in Kenyan Infants With Iron Deficiency
NCT07060872	Not specified	NOT_YET_RECRUITING	the Effect of Formulation on Anxiety in Autist Childre A Randomized Controlled Trial Assesses Spirulina Syrup Plus Risperidone in Children With Non-idiopathic Autism. Anxiety is Measured Using the SCAS (Parent Version) Via Daily Online Surveys for One Week and Throughout a 3-month Follow-up Period.
NCT07345715	Not specified	RECRUITING	Oral Melatonin Versus Nebulized Dexmedetomidine on Emergence Agitation in Children Undergoing Adenotonsillectomy
NCT07495943	Not specified	NOT_YET_RECRUITING	Effects of 2-Aticyto Complex and D-Ribose on Pain and Clinical Course in Patients With Fibromyalgia
NCT00531674	Not specified	COMPLETED	Efficacy of 3 Nutritional Supplements to Improve Diverse Outcomes in Children Under 2 Years of Age and Pregnant Women
NCT00761527	Not specified	COMPLETED	Observation of Side Effects and Effectiveness of Desloratadine (Aerius) Syrup in Filipino Children (Study P05634)
NCT01140516	Not specified	UNKNOWN	Effectiveness of Antibiotics Versus Placebo to Treat Antenatal Hydronephrosis
NCT01721395	Not specified	COMPLETED	Effect of Agave Syrup, Placebo, and No Treatment on Nocturnal Cough and Sleep Quality for Coughing Infants/Toddlers and Their Parents
NCT01800708	Not specified	COMPLETED	Cataract Surgery With Intracameral Triamcinolone in Infants
NCT02064205	Not specified	COMPLETED	Appetite Suppression Trial With Polydextrose
NCT02069665	Not specified	COMPLETED	Effectiveness Study of Integrative Treatment for Pediatric Pneumonia

Clinical evidence (CIViC)

No CIViC predictive evidence (expected for non-precision-medicine drugs).

Pharmacology

Pharmacogenomics

No PharmGKB pharmacogenomic data curated for this drug.

Related molecules

Related molecules

No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).