Thyroid
drugOn this page
Also known as Armour thyroidDessicated thyroidDried thyroidGlandula thyreoidea suisNatureNSC-26492Pig thyroidPorcine thyroidPork thyroidSus scrofa thyroidThyreoidea suisThyroid (pork)Thyroid glandThyroid gland preparationsThyroid powderporcineporkunspecifiedThyroidinum
Summary
Thyroid (CHEMBL2108878) is a phase-3 clinical-stage unknown (ATC H03AA05); indicated across 5 conditions including down syndrome and heart failure.
At a glance
- Status: Max clinical phase 3 (not approved)
- Modality: Unknown
- ATC class: H03AA05
- Indications: 5 conditions
- Clinical trials: 57
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL2108878 |
| Name | Thyroid |
| Type | Unknown |
| Max phase | 3 |
| ATC | H03AA05 |
Also known as: Armour thyroid, Dessicated thyroid, Dried thyroid, Glandula thyreoidea suis, Nature, NSC-26492, Pig thyroid, Porcine thyroid, Pork thyroid, Sus scrofa thyroid, Thyreoidea suis, Thyroid
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
5 indications (0 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).
| Indication | Trial phase | MONDO | EFO |
|---|---|---|---|
| Down syndrome | 3 | MONDO:0008608 | EFO:0001064 |
| heart failure | 3 | MONDO:0005252 | EFO:0003144 |
| hypothyroidism | 2 | MONDO:0005420 | EFO:0004705 |
| type 2 diabetes mellitus | 1 | MONDO:0005148 | MONDO:0005148 |
1 further indication record had no mapped disease name (EFO/MeSH-only) or were duplicates, and are omitted.
Clinical trials
Total trials: 57.
Phase distribution
| Phase | Trials |
|---|---|
| Not specified | 51 |
| PHASE2 | 3 |
| PHASE3 | 1 |
| PHASE2/PHASE3 | 1 |
| PHASE1 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT06345339 | PHASE2/PHASE3 | RECRUITING | A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants |
| NCT02656329 | PHASE3 | TERMINATED | International Study to Determine if AdreView Heart Function Scan Can be Used to Identify Patients With Mild or Moderate Heart Failure (HF) That Benefit From Implanted Medical Device |
| NCT02947035 | PHASE2 | COMPLETED | Molecular Testing to Direct Extent of Initial Thyroid Surgery |
| NCT04124705 | PHASE2 | COMPLETED | A Study of Armour® Thyroid Compared to Synthetic T4 (Levothyroxine) in Previously Hypothyroid Participants |
| NCT05841979 | PHASE2 | COMPLETED | The Lived Experiences Measured Using Rings Pilot Study |
| NCT01557504 | PHASE1 | COMPLETED | A Study to Assess the Pharmacokinetics and the Ability for Pediatric Participants With Type 2 Diabetes to Swallow MK-0431A XR Tablets (MK-0431A-296) |
| NCT03238976 | Not specified | ACTIVE_NOT_RECRUITING | Nature Sounds as a Pain and Anxiety Reducing Strategy in Patients Undergoing Breast Core Biopsy |
| NCT06316895 | Not specified | RECRUITING | The Clinical Outcomes and Prediction of Thermal Ablation for Low-risk Papillary Thyroid Carcinoma |
| NCT06431126 | Not specified | ACTIVE_NOT_RECRUITING | Nature and Animal-assisted Activities |
| NCT06609408 | Not specified | NOT_YET_RECRUITING | The Effect of Nature and Game Based Activities on Older People |
| NCT07022236 | Not specified | RECRUITING | Assessment of Thyroid Dysfunction in Patients Undergoing Haemodialysis at Sohag University Hospital |
| NCT07082712 | Not specified | RECRUITING | Investigate Relationship Between Thyroid Disorders and Acute Coronary Syndrome. |
| NCT07090915 | Not specified | NOT_YET_RECRUITING | The Influence of Natural Sounds on the Well-being of Patients After Orthopaedic Surgery |
| NCT07137624 | Not specified | RECRUITING | Motor Imagery and Action Observation for Gait Function in MS |
| NCT07255482 | Not specified | ACTIVE_NOT_RECRUITING | Mortality Benefit of Ultrasound for Thyroid Nodules Identified With PET Imaging: Non-Inferiority Emulated Target Trial |
| NCT07458451 | Not specified | NOT_YET_RECRUITING | Effect of Nature Sounds During Dental Filling on Anxiety in Older Adults |
| NCT07488585 | Not specified | NOT_YET_RECRUITING | A Novel Ultrasound Probe for Thyroid Imaging and Machine Learning |
| NCT07512999 | Not specified | NOT_YET_RECRUITING | The Effect of Using Nature Sounds and Virtual Reality During the Non-Stress Test |
| NCT07579988 | Not specified | NOT_YET_RECRUITING | Ultrasound Measurement of Thyroid Volume in Term Newborns |
| NCT07612293 | Not specified | NOT_YET_RECRUITING | STAGE-MTC Trial Thyroid Lobectomy With Ipsilateral Central Neck Dissection |
| NCT00571090 | Not specified | COMPLETED | Prediction of Thyroid Cancer From Ultrasonographic Characteristics of Thyroid Nodules |
| NCT01273714 | Not specified | COMPLETED | Subtotal Versus Total Thyroidectomy for Benign Goiter |
| NCT01838031 | Not specified | COMPLETED | Thyroid Screening Protocol During Pregnancy: a Multi-center Prospective Controlled Study |
| NCT02115906 | Not specified | UNKNOWN | Assessment of Changes in Metabolic Activity in Liver & Skeletal Muscle in Patients Suffering From Acromegaly |
| NCT02813733 | Not specified | COMPLETED | Determinants of Thyroid Surgery Outcomes |
| NCT03284840 | Not specified | COMPLETED | Adults Nutrition as a Protective or Health-risk Factor |
| NCT03294005 | Not specified | COMPLETED | Clinical Prediction Thyroid Cancer With Thyroid Ultrasonography |
| NCT03324334 | Not specified | UNKNOWN | Prevalence of Graves Disease in Patients With Ulcerative Colitis |
| NCT03377829 | Not specified | UNKNOWN | A Multicenter Trial of PLA vs. Surgery for Treating PTMC |
| NCT03442998 | Not specified | COMPLETED | Walking Green: Developing an Evidence-base for Nature Prescriptions |
| NCT03518255 | Not specified | COMPLETED | e-Natureza Project - Affective Validation of Nature Images for Hospital Use |
| NCT03578601 | Not specified | COMPLETED | Predictive Parameters for Difficult Tracheal Intubation Identification in Thyroid Surgery |
| NCT03716440 | Not specified | COMPLETED | Effects of Nature Exposure on Smoking Behavior |
| NCT04040673 | Not specified | UNKNOWN | RAman For Thyroid cancER |
| NCT04208503 | Not specified | UNKNOWN | Ultrasound and Functional Thyroid Evaluation |
| NCT04236232 | Not specified | UNKNOWN | The Impact of Subclinical Hypothyroidism on Cardiovascular System |
| NCT04409938 | Not specified | COMPLETED | Progressive Muscle Relaxation and Nature Sounds in Nursing Students |
| NCT04528862 | Not specified | WITHDRAWN | Reducing Error in ER Settings Through Attention Restoration Theory |
| NCT04569513 | Not specified | UNKNOWN | The Analysis of Thyroidectomy and Parathyroidectomy |
| NCT04642235 | Not specified | COMPLETED | Nature and Well-Being Project |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
- Diseases: Down syndrome, heart failure