Triptorelin Acetate
drugOn this page
Also known as Ovugel
Summary
Triptorelin Acetate (CHEMBL5315073) is a phase-3 clinical-stage protein; indicated across 3 conditions including infertility disorder and adenomyosis.
At a glance
- Status: Max clinical phase 3 (not approved)
- Modality: Protein
- Indications: 3 conditions
- Clinical trials: 12
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL5315073 |
| Name | Triptorelin Acetate |
| Type | Protein |
| Max phase | 3 |
Also known as: Ovugel, Triptorelin acetate, TRIPTORELIN ACETATE
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
3 indications (0 at ChEMBL trial phase 4). Phase below is the highest clinical-trial phase recorded for this drug against each disease — not the molecule’s overall approval status (that is in the Summary).
| Indication | Trial phase | MONDO | EFO |
|---|---|---|---|
| infertility disorder | 3 | MONDO:0005047 | EFO:0000545 |
| adenomyosis | 0 | MONDO:0010888 | EFO:1001757 |
1 further indication record had no mapped disease name (EFO/MeSH-only) or were duplicates, and are omitted.
Clinical trials
Total trials: 12.
Phase distribution
| Phase | Trials |
|---|---|
| PHASE4 | 8 |
| PHASE3 | 1 |
| PHASE2 | 1 |
| EARLY_PHASE1 | 1 |
| Not specified | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT01581359 | PHASE4 | COMPLETED | The Effect of Pre-treatment With GnRH Analogues Prior in Vitro Fertilization in Patients With Endometriosis |
| NCT02715232 | PHASE4 | UNKNOWN | Effects of Sex Steroids on the Serotonin System |
| NCT02825290 | PHASE4 | UNKNOWN | Modified Luteal Support for Frozen-Thawed Embryo Transfer - A Prospective Study |
| NCT03809221 | PHASE4 | UNKNOWN | The Effectiveness and Safety of the Prolonged Down-regulation Protocol for Controlled Ovarian Hyperstimulation |
| NCT04724343 | PHASE4 | COMPLETED | Effect of GnRH Agonist vs GnRH Antagonist on IVF/ICSI Outcomes. |
| NCT04724486 | PHASE4 | COMPLETED | Effect of GnRH Agonist vs GnRH Antagonist on Oocyte Morphology During IVF/ICSI |
| NCT04727671 | PHASE4 | COMPLETED | Effect of GnRH Agonist vs GnRH Antagonist on IVF/ICSI Outcomes in Polycystic Ovary Syndrome Patients. |
| NCT04727684 | PHASE4 | COMPLETED | Effect of GnRH Agonist vs GnRH Antagonist on Oocyte Morphology in Polycystic Ovary Syndrome Patients During IVF/ICSI |
| NCT01007851 | PHASE3 | TERMINATED | Single Dose Gonadotropin-releasing Hormone (GnRH) Agonist Administration in the Luteal Phase of GnRH Antagonist Stimulated ICSI-ET Cycles |
| NCT05212857 | PHASE2 | UNKNOWN | Enhanced Systemic Combined With Local Treatment for Primary and Metastatic Lesions in Oligo-metastatic Prostate Cancer |
| NCT05151016 | EARLY_PHASE1 | UNKNOWN | Long-term Use of Mifepristone in the Treatment of Adenomyosis |
| NCT00516490 | Not specified | COMPLETED | GnRH Agonist Administration in the Luteal Phase of ICSI-ET Cycles |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
- Diseases: infertility disorder