Von Willebrand Factor Human
drug drugOn this page
Also known as Human von willebrand factorVon willebrand factorVon willebrand factor (human)humanVon willebrand's factor
Summary
Von Willebrand Factor Human (CHEMBL4298126) is an approved unknown (ATC B02BD10); indicated across 6 conditions including von willebrand disease (hereditary or acquired) and hemophilia a.
At a glance
- Status: Approved (max clinical phase 4)
- Modality: Unknown
- ATC class: B02BD10
- Indications: 6 conditions
- Clinical trials: 4
Identifiers
Drug identity and classification
| Field | Value |
|---|---|
| ChEMBL ID | CHEMBL4298126 |
| Name | Von Willebrand Factor Human |
| Type | Unknown |
| Max phase | 4 |
| ATC | B02BD10 |
Also known as: Human von willebrand factor, Von willebrand factor, Von willebrand factor (human), Von willebrand factor human, human, Von willebrand’s factor, VON WILLEBRAND FACTOR HUMAN
Targets
Targets
No target linkage available.
Bioactivity
No ChEMBL bioactivity rows at pChembl ≥ 5 (expected for biologics / antibodies).
Target pathways
No target-pathway data for this drug (no mapped target genes).
Indications & clinical
Indications
2 approved indications. FDA phase 4, plus an anticancer drug’s labelled cancer uses (which ChEMBL often logs at phase 3).
| Indication | Phase | MONDO | EFO |
|---|---|---|---|
| von Willebrand disease (hereditary or acquired) | 4 | MONDO:0024574 | Orphanet:903 |
| hemophilia A | 4 | MONDO:0010602 | MONDO:0010602 |
1 disease in clinical trials (phase 1–3, investigational — not approved indications). Highest ChEMBL trial phase per disease; a non-cancer approved use is occasionally logged at phase 3 here.
| Disease (in trials) | Phase | MONDO | EFO |
|---|---|---|---|
| hemorrhagic disease | 1 | MONDO:0002243 | MONDO:0002243 |
3 further indication records had no mapped disease name (EFO/MeSH-only) or were duplicates, and are omitted.
Clinical trials
Total trials: 4.
Phase distribution
| Phase | Trials |
|---|---|
| Not specified | 2 |
| PHASE2 | 1 |
| PHASE1 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT03613584 | PHASE2 | UNKNOWN | Von Willebrand Factor Concentrate During ECMO Support |
| NCT00004667 | PHASE1 | COMPLETED | Phase I Study of Human Von Willebrand Factor for Von Willebrand’s Disease |
| NCT02460458 | Not specified | COMPLETED | Type 3 Von Willebrand International Registries Inhibitor Prospective Study |
| NCT05008458 | Not specified | UNKNOWN | Value of Von Willebrand Factor and Copeptin Assay in Children With Febrile Seizures at Sohag University Hospital |
Clinical evidence (CIViC)
No CIViC predictive evidence (expected for non-precision-medicine drugs).
Pharmacology
Pharmacogenomics
No PharmGKB pharmacogenomic data curated for this drug.
Related molecules
Related molecules
No competitor molecules sharing a primary target (ChEMBL phase ≥2 or PubChem drug-class).
Related Atlas pages
- Indicated for: von Willebrand disease (hereditary or acquired), hemophilia A