A1BG-AS1

Summary

A1BG-AS1 (A1BG antisense RNA 1, HGNC:37133) is a long non-coding RNA gene on chromosome 19q13.43.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:37133
Approved symbol	A1BG-AS1
Name	A1BG antisense RNA 1
Location	19q13.43
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ23569
Ensembl gene	ENSG00000268895
Ensembl biotype	lncRNA
Entrez	503538
RNAcentral	URS00007E4F6E — lncRNA, 2175 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000593374, ENST00000593960, ENST00000594950, ENST00000595302, ENST00000599728, ENST00000600379, ENST00000600686, ENST00000670199, ENST00000670460

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000593374 — 3 exons

Exon	Start	End
ENSE00003088284	58347752	58347844
ENSE00003151549	58353321	58353474
ENSE00003199049	58353714	58354425

Expression profiles

Bgee: expression breadth ubiquitous, 204 present calls, max score 89.14.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 5.3472 / max 43.6991, expressed in 1542 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
177830	4.8649	1526
177829	0.4823	255

Top tissues by expression

246 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
vena cava	UBERON:0004087	89.14	silver quality
buccal mucosa cell	CL:0002336	86.98	silver quality
cerebellar vermis	UBERON:0004720	86.51	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	84.93	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.15	gold quality
body of tongue	UBERON:0011876	84.10	gold quality
pons	UBERON:0000988	83.03	silver quality
tongue	UBERON:0001723	82.82	silver quality
pharyngeal mucosa	UBERON:0000355	82.76	silver quality
myocardium	UBERON:0002349	82.46	gold quality
thymus	UBERON:0002370	82.37	gold quality
pericardium	UBERON:0002407	82.35	gold quality
inferior vagus X ganglion	UBERON:0005363	82.35	silver quality
cardia of stomach	UBERON:0001162	82.30	silver quality
pylorus	UBERON:0001166	82.07	silver quality
substantia nigra pars compacta	UBERON:0001965	82.02	silver quality
trachea	UBERON:0003126	81.98	silver quality
superior surface of tongue	UBERON:0007371	81.94	gold quality
right lobe of liver	UBERON:0001114	81.89	gold quality
nipple	UBERON:0002030	81.72	silver quality
subthalamic nucleus	UBERON:0001906	81.68	silver quality
lateral globus pallidus	UBERON:0002476	81.66	silver quality
substantia nigra pars reticulata	UBERON:0001966	81.53	gold quality
dorsal plus ventral thalamus	UBERON:0001897	81.50	silver quality
stromal cell of endometrium	CL:0002255	81.39	gold quality
lateral nuclear group of thalamus	UBERON:0002736	80.99	gold quality
saphenous vein	UBERON:0007318	80.93	silver quality
right uterine tube	UBERON:0001302	80.90	gold quality
medulla oblongata	UBERON:0001896	80.57	silver quality
superior vestibular nucleus	UBERON:0007227	80.23	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.37

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• Low A1BG-AS1 expression is associated with proliferation and invasion of hepatocellular carcinoma. (PMID:30556161)
• Long non-coding RNA A1BG-AS1 promotes tumorigenesis in breast cancer by sponging microRNA-485-5p and consequently increasing expression of FLOT1 expression. (PMID:34115333)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.