A2ML1-AS2

Summary

A2ML1-AS2 (A2ML1 antisense RNA 2, HGNC:41523) is a long non-coding RNA gene on chromosome 12p13.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41523
Approved symbol	A2ML1-AS2
Name	A2ML1 antisense RNA 2
Location	12p13.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000256904
Ensembl biotype	lncRNA
Entrez	106478979
RNAcentral	URS00001BFF15 — lncRNA, 386 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000394240

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000394240 — 2 exons

Exon	Start	End
ENSE00002264074	8820586	8820713
ENSE00002266723	8819816	8820073

Expression profiles

Bgee: expression breadth broad, 86 present calls, max score 85.27.

Top tissues by expression

86 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.27	silver quality
skeletal muscle tissue	UBERON:0001134	70.78	gold quality
ventricular zone	UBERON:0003053	69.85	gold quality
lymph node	UBERON:0000029	65.63	gold quality
bone marrow	UBERON:0002371	60.32	gold quality
monocyte	CL:0000576	60.24	gold quality
duodenum	UBERON:0002114	58.86	gold quality
blood	UBERON:0000178	55.90	gold quality
muscle of leg	UBERON:0001383	54.01	gold quality
gastrocnemius	UBERON:0001388	53.52	gold quality
ectocervix	UBERON:0012249	53.28	gold quality
prefrontal cortex	UBERON:0000451	53.27	gold quality
heart left ventricle	UBERON:0002084	49.82	gold quality
corpus callosum	UBERON:0002336	49.23	silver quality
urinary bladder	UBERON:0001255	48.95	gold quality
popliteal artery	UBERON:0002250	48.66	gold quality
tibial artery	UBERON:0007610	48.57	gold quality
fundus of stomach	UBERON:0001160	48.10	gold quality
left adrenal gland cortex	UBERON:0035825	47.95	gold quality
right lobe of liver	UBERON:0001114	47.87	silver quality
lower esophagus mucosa	UBERON:0035834	47.83	gold quality
kidney	UBERON:0002113	47.77	gold quality
liver	UBERON:0002107	47.26	silver quality
subcutaneous adipose tissue	UBERON:0002190	47.24	gold quality
ascending aorta	UBERON:0001496	47.06	gold quality
thoracic aorta	UBERON:0001515	46.70	gold quality
body of pancreas	UBERON:0001150	46.41	silver quality
cerebellar hemisphere	UBERON:0002245	46.40	gold quality
Brodmann (1909) area 9	UBERON:0013540	46.25	gold quality
heart	UBERON:0000948	46.12	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.65

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.