ACE2-DT

Summary

ACE2-DT (ACE2 divergent transcript, HGNC:56255) is a long non-coding RNA gene on chromosome Xp22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56255
Approved symbol	ACE2-DT
Name	ACE2 divergent transcript
Location	Xp22.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	GS1-594A7.3
Ensembl gene	ENSG00000225833
Ensembl biotype	lncRNA
Entrez	104798195
RNAcentral	URS00000D3355 — ncRNA, 574 nt, 2 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000421585, ENST00000742836, ENST00000742837, ENST00000742838

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000421585 — 2 exons

Exon	Start	End
ENSE00004080695	15602858	15602981
ENSE00004080697	15621012	15621485

Expression profiles

Bgee: expression breadth broad, 69 present calls, max score 64.76.

Top tissues by expression

69 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
placenta	UBERON:0001987	64.76	gold quality
skeletal muscle tissue	UBERON:0001134	58.46	gold quality
islet of Langerhans	UBERON:0000006	54.82	gold quality
duodenum	UBERON:0002114	54.66	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	53.59	gold quality
right adrenal gland	UBERON:0001233	53.28	gold quality
small intestine	UBERON:0002108	53.02	gold quality
right adrenal gland cortex	UBERON:0035827	52.99	gold quality
small intestine Peyer’s patch	UBERON:0003454	52.23	gold quality
blood	UBERON:0000178	52.05	silver quality
intestine	UBERON:0000160	51.75	gold quality
muscle of leg	UBERON:0001383	51.64	gold quality
endometrium	UBERON:0001295	51.11	silver quality
saliva-secreting gland	UBERON:0001044	51.07	gold quality
minor salivary gland	UBERON:0001830	50.91	gold quality
gastrocnemius	UBERON:0001388	50.02	gold quality
gall bladder	UBERON:0002110	49.49	gold quality
heart	UBERON:0000948	48.96	gold quality
cortex of kidney	UBERON:0001225	48.56	gold quality
heart left ventricle	UBERON:0002084	48.38	gold quality
kidney	UBERON:0002113	47.60	gold quality
caudate nucleus	UBERON:0001873	47.49	gold quality
metanephros cortex	UBERON:0010533	47.26	gold quality
adult mammalian kidney	UBERON:0000082	46.78	gold quality
body of pancreas	UBERON:0001150	46.69	silver quality
stomach	UBERON:0000945	46.47	gold quality
right atrium auricular region	UBERON:0006631	45.52	gold quality
adrenal gland	UBERON:0002369	45.45	gold quality
ectocervix	UBERON:0012249	45.38	gold quality
colon	UBERON:0001155	45.28	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.70

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.