ACSS3-AS1

Summary

ACSS3-AS1 (ACSS3 antisense RNA 1, HGNC:58286) is a long non-coding RNA gene on chromosome 12q21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58286
Approved symbol	ACSS3-AS1
Name	ACSS3 antisense RNA 1
Location	12q21.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258026
Ensembl biotype	lncRNA
Entrez	107984535
RNAcentral	URS00000CCACD — lncRNA, 882 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000547123, ENST00000653205, ENST00000753047

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000547123 — 5 exons

Exon	Start	End
ENSE00002348987	81094375	81094732
ENSE00002367460	81117966	81118052
ENSE00002410837	81124399	81124513
ENSE00002414066	81104769	81104828
ENSE00002416884	81125584	81125845

Expression profiles

Bgee: expression breadth broad, 85 present calls, max score 96.95.

Top tissues by expression

85 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	96.95	gold quality
right testis	UBERON:0004534	73.40	gold quality
testis	UBERON:0000473	69.74	gold quality
skeletal muscle tissue	UBERON:0001134	69.57	gold quality
left testis	UBERON:0004533	69.17	gold quality
tonsil	UBERON:0002372	68.83	gold quality
bone marrow cell	CL:0002092	65.64	silver quality
hindlimb stylopod muscle	UBERON:0004252	62.94	gold quality
small intestine	UBERON:0002108	62.50	silver quality
calcaneal tendon	UBERON:0003701	62.14	gold quality
liver	UBERON:0002107	61.32	gold quality
colonic epithelium	UBERON:0000397	60.53	silver quality
endocervix	UBERON:0000458	58.25	gold quality
urinary bladder	UBERON:0001255	58.10	silver quality
uterine cervix	UBERON:0000002	55.88	gold quality
prefrontal cortex	UBERON:0000451	55.01	gold quality
sural nerve	UBERON:0015488	54.94	silver quality
kidney	UBERON:0002113	53.08	gold quality
monocyte	CL:0000576	51.89	gold quality
cortex of kidney	UBERON:0001225	51.17	gold quality
multicellular organism	UBERON:0000468	51.05	gold quality
endometrium	UBERON:0001295	50.62	gold quality
lung	UBERON:0002048	50.57	gold quality
adult mammalian kidney	UBERON:0000082	50.26	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.09	gold quality
blood	UBERON:0000178	48.99	silver quality
stomach	UBERON:0000945	48.43	gold quality
muscle of leg	UBERON:0001383	48.24	gold quality
corpus callosum	UBERON:0002336	47.49	silver quality
right lobe of liver	UBERON:0001114	47.00	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.77

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.