ACTN3-AS1

Summary

ACTN3-AS1 (ACTN3 antisense RNA 1, HGNC:58248) is a long non-coding RNA gene on chromosome 11q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58248
Approved symbol	ACTN3-AS1
Name	ACTN3 antisense RNA 1
Location	11q13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250105
Ensembl biotype	lncRNA
Entrez	139355234
RNAcentral	URS0000048A50 — lncRNA, 580 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000504911

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000504911 — 2 exons

Exon	Start	End
ENSE00002040858	66560165	66560384
ENSE00002047696	66558866	66559225

Expression profiles

Bgee: expression breadth broad, 85 present calls, max score 74.04.

Top tissues by expression

85 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
skeletal muscle tissue	UBERON:0001134	74.04	gold quality
hindlimb stylopod muscle	UBERON:0004252	73.23	gold quality
left testis	UBERON:0004533	63.94	gold quality
right testis	UBERON:0004534	63.57	gold quality
ganglionic eminence	UBERON:0004023	63.36	gold quality
testis	UBERON:0000473	62.78	gold quality
cortex of kidney	UBERON:0001225	58.95	gold quality
muscle of leg	UBERON:0001383	58.85	gold quality
gastrocnemius	UBERON:0001388	55.59	gold quality
primary visual cortex	UBERON:0002436	54.01	gold quality
islet of Langerhans	UBERON:0000006	53.78	gold quality
prefrontal cortex	UBERON:0000451	53.35	gold quality
cerebellar hemisphere	UBERON:0002245	52.08	gold quality
cerebellar cortex	UBERON:0002129	52.03	gold quality
cerebellum	UBERON:0002037	52.02	gold quality
monocyte	CL:0000576	51.90	silver quality
right hemisphere of cerebellum	UBERON:0014890	51.17	gold quality
placenta	UBERON:0001987	50.93	gold quality
gall bladder	UBERON:0002110	50.26	gold quality
right lobe of liver	UBERON:0001114	50.05	gold quality
blood	UBERON:0000178	48.98	silver quality
calcaneal tendon	UBERON:0003701	48.01	silver quality
frontal cortex	UBERON:0001870	47.79	gold quality
right ovary	UBERON:0002118	46.54	gold quality
Brodmann (1909) area 9	UBERON:0013540	46.54	gold quality
brain	UBERON:0000955	46.46	gold quality
putamen	UBERON:0001874	45.99	gold quality
cerebral cortex	UBERON:0000956	45.88	gold quality
right frontal lobe	UBERON:0002810	45.65	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	45.29	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.26

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.