ACTR3-AS1

Summary

ACTR3-AS1 (ACTR3 antisense RNA 1, HGNC:53965) is a long non-coding RNA gene on chromosome 2q14.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53965
Approved symbol	ACTR3-AS1
Name	ACTR3 antisense RNA 1
Location	2q14.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC104653.1
Ensembl gene	ENSG00000228857
Ensembl biotype	lncRNA
Entrez	101060091
RNAcentral	URS000075A0DA — lncRNA, 590 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 41 — 41 lncRNA

ENST00000420579, ENST00000435407, ENST00000446401, ENST00000602760, ENST00000687580, ENST00000689404, ENST00000827862, ENST00000827863, ENST00000827864, ENST00000827865, ENST00000827866, ENST00000827867, ENST00000827868, ENST00000827869, ENST00000827870, ENST00000827871, ENST00000827872, ENST00000827873, ENST00000827874, ENST00000827875, ENST00000827876, ENST00000827877, ENST00000827878, ENST00000827879, ENST00000827880, ENST00000827881, ENST00000827882, ENST00000827883, ENST00000827884, ENST00000827885, ENST00000827886, ENST00000827887, ENST00000827888, ENST00000827889, ENST00000827890, ENST00000827891, ENST00000827892, ENST00000827893, ENST00000827894, ENST00000827895, ENST00000827896

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000420579 — 2 exons

Exon	Start	End
ENSE00001628229	113831049	113831428
ENSE00001797545	113831530	113831727

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 95.47.

FANTOM5 (CAGE): breadth broad, TPM avg 1.8387 / max 159.8600, expressed in 411 samples.

FANTOM5 promoters (6 alternative TSS)

Promoter ID	TPM avg	Samples expressed
30341	0.5266	131
30342	0.4090	113
30345	0.3866	164
30344	0.3290	91
30346	0.1285	32
30343	0.0591	32

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	95.47	gold quality
right testis	UBERON:0004534	77.64	gold quality
left testis	UBERON:0004533	77.21	gold quality
testis	UBERON:0000473	76.60	gold quality
tonsil	UBERON:0002372	73.38	gold quality
lymph node	UBERON:0000029	72.83	gold quality
cortical plate	UBERON:0005343	72.52	gold quality
vermiform appendix	UBERON:0001154	71.17	gold quality
ventricular zone	UBERON:0003053	69.87	gold quality
right adrenal gland cortex	UBERON:0035827	69.40	gold quality
bone marrow cell	CL:0002092	69.20	silver quality
right adrenal gland	UBERON:0001233	69.12	gold quality
granulocyte	CL:0000094	68.94	gold quality
nucleus accumbens	UBERON:0001882	68.08	gold quality
stromal cell of endometrium	CL:0002255	68.05	gold quality
spleen	UBERON:0002106	67.44	gold quality
colonic epithelium	UBERON:0000397	66.96	silver quality
left adrenal gland	UBERON:0001234	66.78	gold quality
blood	UBERON:0000178	66.67	gold quality
caudate nucleus	UBERON:0001873	66.39	gold quality
bone marrow	UBERON:0002371	66.34	gold quality
adrenal gland	UBERON:0002369	66.30	gold quality
left adrenal gland cortex	UBERON:0035825	66.14	gold quality
putamen	UBERON:0001874	66.13	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	64.84	gold quality
prefrontal cortex	UBERON:0000451	64.26	gold quality
amygdala	UBERON:0001876	63.96	gold quality
islet of Langerhans	UBERON:0000006	63.94	gold quality
leukocyte	CL:0000738	63.83	gold quality
Ammon’s horn	UBERON:0001954	63.28	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.74

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.